Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Simon P. Teague"'
Publikováno v:
ADMET and DMPK, Vol 5, Iss 1, Pp 14-38 (2017)
The drug discovery process can be accelerated by chromatographic profiling of the analogs to model in vivo distribution and the major non-specific binding. A balanced potency and chromatographically determined membrane and protein binding (IAM MB/PB)
Externí odkaz:
https://doaj.org/article/a29c5ad30ea64a099af98ff95d72f461
Autor:
Per Bäckman, Antonio Cabal, Andy Clark, Carsten Ehrhardt, Ben Forbes, Jayne Hastedt, Anthony Hickey, Guenther Hochhaus, Wenlei Jiang, Stavros Kassinos, Philip J. Kuehl, David Prime, Yoen-Ju Son, Simon P. Teague, Ulrika Tehler, Jennifer Wylie
Publikováno v:
Molecular Pharmaceutics. 19:2040-2047
This work is the second in a series of publications outlining the fundamental principles and proposed design of a biopharmaceutics classifications system for inhaled drugs and drug products (the iBCS). Here, a mechanistic computer-based model has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e43bf5bce93c041df00495ef002eafe
https://doi.org/10.1021/acs.molpharmaceut.2c00112
https://doi.org/10.1021/acs.molpharmaceut.2c00112