Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Simon P. Goedegebuure"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dendritic cells (DCs) play a central role in the orchestration of effective T cell responses against tumors. However, their functional behavior is context-dependent. DC type, transcriptional program, location, intratumoral factors, and inflammatory m
Externí odkaz:
https://doaj.org/article/4b57a07e1bda42679b4295753dcebc0a
Autor:
Orit Rozenblatt-Rosen, Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood, Orr Ashenberg, Ethan Cerami, Robert J. Coffey, Emek Demir, Li Ding, Edward D. Esplin, James M. Ford, Jeremy Goecks, Sharmistha Ghosh, Joe W. Gray, Justin Guinney, Sean E. Hanlon, Shannon K. Hughes, E. Shelley Hwang, Christine A. Iacobuzio-Donahue, Judit Jané-Valbuena, Bruce E. Johnson, Ken S. Lau, Tracy Lively, Sarah A. Mazzilli, Dana Pe’er, Sandro Santagata, Alex K. Shalek, Denis Schapiro, Michael P. Snyder, Peter K. Sorger, Avrum E. Spira, Sudhir Srivastava, Kai Tan, Robert B. West, Elizabeth H. Williams, Denise Aberle, Samuel I. Achilefu, Foluso O. Ademuyiwa, Andrew C. Adey, Rebecca L. Aft, Rachana Agarwal, Ruben A. Aguilar, Fatemeh Alikarami, Viola Allaj, Christopher Amos, Robert A. Anders, Michael R. Angelo, Kristen Anton, Jon C. Aster, Ozgun Babur, Amir Bahmani, Akshay Balsubramani, David Barrett, Jennifer Beane, Diane E. Bender, Kathrin Bernt, Lynne Berry, Courtney B. Betts, Julie Bletz, Katie Blise, Adrienne Boire, Genevieve Boland, Alexander Borowsky, Kristopher Bosse, Matthew Bott, Ed Boyden, James Brooks, Raphael Bueno, Erik A. Burlingame, Qiuyin Cai, Joshua Campbell, Wagma Caravan, Hassan Chaib, Joseph M. Chan, Young Hwan Chang, Deyali Chatterjee, Ojasvi Chaudhary, Alyce A. Chen, Bob Chen, Changya Chen, Chia-hui Chen, Feng Chen, Yu-An Chen, Milan G. Chheda, Koei Chin, Roxanne Chiu, Shih-Kai Chu, Rodrigo Chuaqui, Jaeyoung Chun, Luis Cisneros, Graham A. Colditz, Kristina Cole, Natalie Collins, Kevin Contrepois, Lisa M. Coussens, Allison L. Creason, Daniel Crichton, Christina Curtis, Tanja Davidsen, Sherri R. Davies, Ino de Bruijn, Laura Dellostritto, Angelo De Marzo, David G. DeNardo, Dinh Diep, Sharon Diskin, Xengie Doan, Julia Drewes, Stephen Dubinett, Michael Dyer, Jacklynn Egger, Jennifer Eng, Barbara Engelhardt, Graham Erwin, Laura Esserman, Alex Felmeister, Heidi S. Feiler, Ryan C. Fields, Stephen Fisher, Keith Flaherty, Jennifer Flournoy, Angelo Fortunato, Allison Frangieh, Jennifer L. Frye, Robert S. Fulton, Danielle Galipeau, Siting Gan, Jianjiong Gao, Long Gao, Peng Gao, Vianne R. Gao, Tim Geiger, Ajit George, Gad Getz, Marios Giannakis, David L. Gibbs, William E. Gillanders, Simon P. Goedegebuure, Alanna Gould, Kate Gowers, William Greenleaf, Jeremy Gresham, Jennifer L. Guerriero, Tuhin K. Guha, Alexander R. Guimaraes, David Gutman, Nir Hacohen, Sean Hanlon, Casey R. Hansen, Olivier Harismendy, Kathleen A. Harris, Aaron Hata, Akimasa Hayashi, Cody Heiser, Karla Helvie, John M. Herndon, Gilliam Hirst, Frank Hodi, Travis Hollmann, Aaron Horning, James J. Hsieh, Shannon Hughes, Won Jae Huh, Stephen Hunger, Shelley E. Hwang, Heba Ijaz, Benjamin Izar, Connor A. Jacobson, Samuel Janes, Reyka G. Jayasinghe, Lihua Jiang, Brett E. Johnson, Bruce Johnson, Tao Ju, Humam Kadara, Klaus Kaestner, Jacob Kagan, Lukas Kalinke, Robert Keith, Aziz Khan, Warren Kibbe, Albert H. Kim, Erika Kim, Junhyong Kim, Annette Kolodzie, Mateusz Kopytra, Eran Kotler, Robert Krueger, Kostyantyn Krysan, Anshul Kundaje, Uri Ladabaum, Blue B. Lake, Huy Lam, Rozelle Laquindanum, Ashley M. Laughney, Hayan Lee, Marc Lenburg, Carina Leonard, Ignaty Leshchiner, Rochelle Levy, Jerry Li, Christine G. Lian, Kian-Huat Lim, Jia-Ren Lin, Yiyun Lin, Qi Liu, Ruiyang Liu, William J.R. Longabaugh, Teri Longacre, Cynthia X. Ma, Mary Catherine Macedonia, Tyler Madison, Christopher A. Maher, Anirban Maitra, Netta Makinen, Danika Makowski, Carlo Maley, Zoltan Maliga, Diego Mallo, John Maris, Nick Markham, Jeffrey Marks, Daniel Martinez, Robert J. Mashl, Ignas Masilionais, Jennifer Mason, Joan Massagué, Pierre Massion, Marissa Mattar, Richard Mazurchuk, Linas Mazutis, Eliot T. McKinley, Joshua F. McMichael, Daniel Merrick, Matthew Meyerson, Julia R. Miessner, Gordon B. Mills, Meredith Mills, Suman B. Mondal, Motomi Mori, Yuriko Mori, Elizabeth Moses, Yael Mosse, Jeremy L. Muhlich, George F. Murphy, Nicholas E. Navin, Michel Nederlof, Reid Ness, Stephanie Nevins, Milen Nikolov, Ajit Johnson Nirmal, Garry Nolan, Edward Novikov, Brendan O’Connell, Michael Offin, Stephen T. Oh, Anastasiya Olson, Alex Ooms, Miguel Ossandon, Kouros Owzar, Swapnil Parmar, Tasleema Patel, Gary J. Patti, Itsik Pe'er, Tao Peng, Daniel Persson, Marvin Petty, Hanspeter Pfister, Kornelia Polyak, Kamyar Pourfarhangi, Sidharth V. Puram, Qi Qiu, Álvaro Quintanal-Villalonga, Arjun Raj, Marisol Ramirez-Solano, Rumana Rashid, Ashley N. Reeb, Mary Reid, Adam Resnick, Sheila M. Reynolds, Jessica L. Riesterer, Scott Rodig, Joseph T. Roland, Sonia Rosenfield, Asaf Rotem, Sudipta Roy, Charles M. Rudin, Marc D. Ryser, Maria Santi-Vicini, Kazuhito Sato, Deborah Schrag, Nikolaus Schultz, Cynthia L. Sears, Rosalie C. Sears, Subrata Sen, Triparna Sen, Alex Shalek, Jeff Sheng, Quanhu Sheng, Kooresh I. Shoghi, Martha J. Shrubsole, Yu Shyr, Alexander B. Sibley, Kiara Siex, Alan J. Simmons, Dinah S. Singer, Shamilene Sivagnanam, Michal Slyper, Artem Sokolov, Sheng-Kwei Song, Austin Southard-Smith, Avrum Spira, Janet Stein, Phillip Storm, Elizabeth Stover, Siri H. Strand, Timothy Su, Damir Sudar, Ryan Sullivan, Lea Surrey, Mario Suvà, Nadezhda V. Terekhanova, Luke Ternes, Lisa Thammavong, Guillaume Thibault, George V. Thomas, Vésteinn Thorsson, Ellen Todres, Linh Tran, Madison Tyler, Yasin Uzun, Anil Vachani, Eliezer Van Allen, Simon Vandekar, Deborah J. Veis, Sébastien Vigneau, Arastoo Vossough, Angela Waanders, Nikhil Wagle, Liang-Bo Wang, Michael C. Wendl, Robert West, Chi-yun Wu, Hao Wu, Hung-Yi Wu, Matthew A. Wyczalkowski, Yubin Xie, Xiaolu Yang, Clarence Yapp, Wenbao Yu, Yinyin Yuan, Dadong Zhang, Kun Zhang, Mianlei Zhang, Nancy Zhang, Yantian Zhang, Yanyan Zhao, Daniel Cui Zhou, Zilu Zhou, Houxiang Zhu, Qin Zhu, Xiangzhu Zhu, Yuankun Zhu, Xiaowei Zhuang
Publikováno v:
Cell
Crucial transitions in cancer-including tumor initiation, local expansion, metastasis, and therapeutic resistance-involve complex interactions between cells within the dynamic tumor ecosystem. Transformative single-cell genomics technologies and spat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ea82738e14282269df985158663c08
https://doi.org/10.1016/j.cell.2020.03.053
https://doi.org/10.1016/j.cell.2020.03.053
Autor:
Ivy Wilkinson-Ryan, Julius Kim, Sojung Kim, Ferhat Ak, Lindzy Dodson, Marco Colonna, Matthew Powell, David Mutch, Dirk Spitzer, Ted Hansen, Simon P Goedegebuure, David Curiel, William Hawkins
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125851 (2015)
One strategy in cancer immunotherapy is to capitalize on the key immunoregulatory and antigen presenting capabilities of dendritic cells (DCs). This approach is dependent on efficient delivery of tumor specific antigens to DCs, which subsequently ind
Externí odkaz:
https://doaj.org/article/ffb1fd41b03042b4ba23bd993635e70e
Autor:
Timothy Schappe, Miriam T. Jacobs, Todd A. Fehniger, Melissa M. Berrien-Elliott, Alice Zhou, Keenan J. Robbins, Bradley A. Krasnick, Celia C. Cubitt, Nancy D. Marin, Lynne Marsala, Christopher Wetzel, Michelle Becker-Hapak, Jennifer A. Foltz, Pamela Wong, Ryan C. Fields, Leah Conant, David A. Russler-Germain, Jennifer Tran, Mark P. Foster, Simon P. Goedegebuure
Publikováno v:
Clin Cancer Res
Purpose:Treatment of advanced melanoma is a clinical challenge. Natural killer (NK) cells are a promising cellular therapy for T cell–refractory cancers, but are frequently deficient or dysfunctional in patients with melanoma. Thus, new strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8496c86b6f83a236ec5ad44c4240a323
https://europepmc.org/articles/PMC8416927/
https://europepmc.org/articles/PMC8416927/
Publikováno v:
Journal of the American College of Surgeons. 231:S161-S162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62cdce48f69705047b2bf4955024260f
https://doi.org/10.1016/j.jamcollsurg.2020.07.524
https://doi.org/10.1016/j.jamcollsurg.2020.07.524
Autor:
Andrea Wang-Gillam, Danielle Carpenter, Timothy J. Eberlein, David G. DeNardo, David C. Linehan, Jonathan B. Mitchem, Stacey Plambeck-Suess, Allese Mayer, Brian A. Belt, Roheena Z. Panni, Simon P. Goedegebuure, Anjali D. Deshpande, Brian D. Goetz, Lori A. Worley, Dominic E. Sanford
Publikováno v:
Clinical Cancer Research. 19:3404-3415
Purpose: To determine the role of the CCL2/CCR2 axis and inflammatory monocytes (CCR2+/CD14+) as immunotherapeutic targets in the treatment of pancreatic cancer. Experimental Design: Survival analysis was conducted to determine if the prevalence of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55342c8aaee76db201df7c38b8631533
https://doi.org/10.1158/1078-0432.ccr-13-0525
https://doi.org/10.1158/1078-0432.ccr-13-0525
Autor:
Savas D. Soysal, I. Wilkinson-Ryan, T. Mohanakumar, E. Huarte, Simon P. Goedegebuure, Timothy P. Fleming, William E. Gillanders, John M. Herndon, Xuehong Zhang, Venkataswarup Tiriveedhi, Lijin Li, Daniel Oertli, J. Kan-Mitchell, Simone Muenst
Publikováno v:
Breast cancer research and treatment. 147(3)
Mammaglobin-A (MAM-A) is a secretory protein that is overexpressed in 80 % of human breast cancers. Its near-universal expression in breast cancer as well as its exquisite tissue specificity makes it an attractive target for a breast cancer preventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3487d1ff99ea77fe5bc13aa12764fe7a
https://pubmed.ncbi.nlm.nih.gov/25212176
https://pubmed.ncbi.nlm.nih.gov/25212176
Autor:
W. Hawkins, David G. Mutch, M.A. Powell, Dirk Spitzer, Pratibha Binder, Simon P. Goedegebuure, Mary C. Hornick
Publikováno v:
Gynecologic Oncology. 137:67-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::829de72218665a747d6a96060dd8f605
https://doi.org/10.1016/j.ygyno.2015.01.160
https://doi.org/10.1016/j.ygyno.2015.01.160
Autor:
Andrea Wang-Gillam, David C. Linehan, Steven M. Strasberg, David G. DeNardo, Ryan C. Fields, A. Craig Lockhart, William G. Hawkins, Matthew R. Porembka, Roheena Z. Panni, Brian A. Belt, Goldie Lin, Jonathan B. Mitchem, Simon P. Goedegebuure, Dominic E. Sanford, Stacey Plambeck-Suess
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by abundant granulocytic myeloid-derived suppressor cells (G-MDSC = CD45+/Lin﹣/CD33+/CD11b+/CD15+), which infiltrate tumors and suppress anti-tumor immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cd6e36f8e93c4795711ab190a252b2
https://europepmc.org/articles/PMC3786568/
https://europepmc.org/articles/PMC3786568/
Autor:
Christopher G. Maher, Elizabeth Pittman, Timothy P. Fleming, Ha X. Dang, Nicole M. White, Ryan C. Fields, Simon P. Goedegebuure, Julie G. Grossman, Robert S. Fulton, Jessica Silva-Fisher, Christopher R. Cabanski, Matthew S. Strand, Richard Wilson, Albert C. Lockhart, Timothy J. Ley
Publikováno v:
Cancer Research. 75:169-169
Colorectal Cancer (CRC) is the most common gastrointestinal malignancy in the U.S.A. Approximately 50% of patients with CRC develops metastatic disease (mCRC) with a 5-year survival of less than 20%. To date, colorectal cancer research has primarily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714a551a420f72be35bf917660387dec
https://doi.org/10.1158/1538-7445.am2015-169
https://doi.org/10.1158/1538-7445.am2015-169