Localised release of matrix metallopeptidase 8 in fatal cerebral malaria

Autor: Athina Georgiadou, Praveena Naidu, Sophie Walsh, Steve Kamiza, Valentina Barrera, Simon P Harding, Christopher A Moxon, Aubrey J Cunnington

Publikováno v: Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)

Abstract Objective Cerebral malaria (CM) is a complication of Plasmodium falciparum malaria, in which progressive brain swelling is associated with sequestration of parasites and impaired barrier function of the cerebral microvascular endothelium. To

Externí odkaz: https://doaj.org/article/04c405dea18a4403bd151336f37fe056

SynPharm: A Guide to PHARMACOLOGY Database Tool for Designing Drug Control into Engineered Proteins

Autor: Sam M. Ireland, Christopher Southan, Alazne Dominguez-Monedero, Simon D. Harding, Joanna L. Sharman, Jamie A. Davies

Publikováno v: ACS Omega, Vol 3, Iss 7, Pp 7993-8002 (2018)

Externí odkaz: https://doaj.org/article/3b705e012e4a48eb910cc3f8d3016bc0

Radial shape discrimination testing for new-onset neovascular age-related macular degeneration in at-risk eyes.

Autor: Noelia Pitrelli Vazquez, Simon P Harding, Heinrich Heimann, Gabriela Czanner, Paul C Knox

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0207342 (2018)

We investigated the performance of the handheld radial shape discrimination (hRSD) test in detecting the development of neovascular AMD (nAMD) in a prospective, longitudinal, observational study. Patients diagnosed with unilateral nAMD, with no nAMD

Externí odkaz: https://doaj.org/article/96ee33a4bcc8456aaadc7a78c4370cfb

Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography

Autor: Nattapon Boonarpha, Yalin Zheng, Alexandros N. Stangos, Huiqi Lu, Ankur Raj, Gabriela Czanner, Simon P. Harding, Jayashree Nair-Sahni

Publikováno v: International Journal of Ophthalmology, Vol 8, Iss 3, Pp 484-491 (2015)

AIM:To describe and evaluate a standardized protocol for measuring the choroidal thickness (ChT) using enhanced depth imaging optical coherence tomography (EDI OCT).METHODS:Single 9 mm EDI OCT line scans across the fovea were used for this study. The

Externí odkaz: https://doaj.org/article/3bcaf964d71f4f71acfbafe38871a6e5

The association between serum lipids and intraocular pressure in 2 large United Kingdom cohorts

Autor: Kian M. Madjedi, Kelsey V. Stuart, Sharon Y.L. Chua, Robert N. Luben, Alasdair Warwick, Louis R. Pasquale, Jae H. Kang, Janey L. Wiggs, Marleen A.H. Lentjes, Hugues Aschard, Naveed Sattar, Paul J. Foster, Anthony P. Khawaja, Mark Chia, Ron Do, Alan Kastner, Jihye Kim, Giovanni Montesano, Denize Atan, Tariq Aslam, Sarah A. Barman, Jenny H. Barrett, Paul Bishop, Peter Blows, Catey Bunce, Roxana O. Carare, Usha Chakravarthy, Michelle Chan, David P. Crabb, Philippa M. Cumberland, Alexander Day, Parul Desai, Bal Dhillon, Andrew D. Dick, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John E.J. Gallacher, David F. Garway-Heath, Jane Gibson, Dan Gore, Jeremy A. Guggenheim, Chris J. Hammond, Alison Hardcastle, Simon P. Harding, Ruth E. Hogg, Pirro Hysi, Pearse A. Keane, Sir Peng T. Khaw, Gerassimos Lascaratos, Andrew J. Lotery, Tom Macgillivray, Sarah Mackie, Keith Martin, Michelle McGaughey, Bernadette McGuinness, Gareth J. McKay, Martin McKibbin, Danny Mitry, Tony Moore, James E. Morgan, Zaynah A. Muthy, Eoin O’Sullivan, Chris G. Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Jugnoo S. Rahi, Alicja R. Rudnikca, Jay Self, Sobha Sivaprasad, David Steel, Irene Stratton, Nicholas Strouthidis, Cathie Sudlow, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Veronique Vitart, Stephen A. Vernon, Ananth C. Viswanathan, Cathy Williams, Katie Williams, Jayne V. Woodside, MaxM. Yates, Jennifer Yip, Yalin Zheng

Publikováno v: Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium, Madjedi, K M, Stuart, K V, Chua, S Y L, Luben, R N, Warwick, A, Pasquale, L R, Kang, J H, Wiggs, J L, Lentjes, M A H, Aschard, H, Sattar, N, Foster, P J, Khawaja, A P, Chia, M, Do, R, Kastner, A, Kim, J, Montesano, G, Atan, D, Aslam, T, Barman, S A, Barrett, J H, Bishop, P, Blows, P, Bunce, C, Carare, R O, Chakravarthy, U, Chan, M, Crabb, D P, Cumberland, P M, Day, A, Desai, P, Dhillon, B, Dick, A D, Egan, C, Ennis, S, Foster, P, Fruttiger, M, Gallacher, J E J, Garway-Heath, D F, Gibson, J, Gore, D, Hogg, R E, McGaughey, M, McGuinness, B, McKay, G J, Paterson, E, Peto, T, Steel, D & Woodside, J V 2022, ' The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts ', Ophthalmology, vol. 129, no. 9, pp. 986-996 . https://doi.org/10.1016/j.ophtha.2022.04.023
Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium 2022, ' The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts ', Ophthalmology, vol. 129, no. 9, pp. 986-996 . https://doi.org/10.1016/j.ophtha.2022.04.023
Ophthalmology: Journal of The American Academy of Ophthalmology
Ophthalmology: Journal of The American Academy of Ophthalmology, 2022, 129 (9), pp.986-996. ⟨10.1016/j.ophtha.2022.04.023⟩
Ophthalmology, 129(9), 986-996. Elsevier Inc.

Purpose: Serum lipids are modifiable, routinely collected blood test features associated with cardiovascular health. We examined the association of commonly collected serum lipid measures (total cholesterol [TC], high-density lipoprotein cholesterol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee73fd6f3ad69cfc1b0fa0ee7b1daba
https://eprints.soton.ac.uk/470583/