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pro vyhledávání: '"Simon N. Smith"'
Publikováno v:
Organic & Biomolecular Chemistry. 20:6384-6393
The first catalytic asymmetric addition of azide to carbonyl centres has been reported – a hypermodified Cinchona alkaloid-derived organocatalyst promotes the addition of trimethylsilyl azide to glutaric anhydrides.
Autor:
Stephen J. Connon, Simon N. Smith
Publikováno v:
European Journal of Organic Chemistry. 2021:5540-5544
Publikováno v:
Organicbiomolecular chemistry. 20(32)
An unprecedented organocatalytic process involving the asymmetric addition of azide to
Publikováno v:
Chemistry – A European Journal. 26:13378-13382
The first divergent synthesis of both γ-amino acid and γ-lactam derivatives from meso-glutaric anhydrides is described. The organocatalytic desymmetrisation with TMSN3 relies on controlled generation of a nucleophilic ammonium azide species mediate
Autor:
Esther Crawley, Simon N Smith
Publikováno v:
Archives of disease in childhood. 98(7)
A 15-year-old girl comes to your outpatient clinic with a 6-month history of fatigue, headaches, nausea and muscle pain. Clinical examination and investigations are normal and you make a diagnosis of chronic fatigue syndrome/myalgic encephalomyelitis