Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Simon N. Robinson"'
Autor:
Barbara Savoldo, Nisha Ghatwai, Mingmei Li, Leonid S. Metelitsa, Amy N. Courtney, Olga Dakhova, Cynthia N Chauvin-Fleurence, Xin Xu, Antonino Montalbano, Tali Raveh-Sadka, Erica J Di Pierro, Ho Ngai, Simon N. Robinson, Andras Heczey, Gianpietro Dotti, Ka Liu, Bin Liu
Publikováno v:
Nature Medicine. 26:1686-1690
Vα24-invariant natural killer T (NKT) cells have shown potent anti-tumor properties in murine tumor models and have been linked to favorable outcomes in patients with cancer. However, low numbers of these cells in humans have hindered their clinical
Autor:
Carlos A. Ramos, Amy N. Courtney, Simon N. Robinson, Olga Dakhova, Premal D. Lulla, Rammurti T. Kamble, George Carrum, Tao Wang, Chunchao Zhang, Erica J. Di Pierro, Leonid S. Metelitsa
Publikováno v:
Transplantation and Cellular Therapy. 28:S54
Autor:
Nina Shah, Beatriz Martin-Antonio, Hong Yang, Stephanie Ku, Dean A Lee, Laurence J N Cooper, William K Decker, Sufang Li, Simon N Robinson, Takuya Sekine, Simrit Parmar, John Gribben, Michael Wang, Katy Rezvani, Eric Yvon, Amer Najjar, Jared Burks, Indreshpal Kaur, Richard E Champlin, Catherine M Bollard, Elizabeth J Shpall
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76781 (2013)
Natural killer (NK) cells are important mediators of anti-tumor immunity and are active against several hematologic malignancies, including multiple myeloma (MM). Umbilical cord blood (CB) is a promising source of allogeneic NK cells but large scale
Externí odkaz:
https://doaj.org/article/c37a7d4c76584050ad3e3bcf2660a4c7
Autor:
William K Decker, Nina Shah, Dongxia Xing, Ruth Lapushin, Sufang Li, Simon N Robinson, Hong Yang, Simrit Parmar, Matthew M Halpert, Michael J Keating, John G Gribben, Jeffrey J Molldrem, Elizabeth J Shpall, William G Wierda
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51390 (2012)
Though remissions have been observed following allo-HSCT for the treatment of CLL, many CLL patients are ineligible for transplant due to the lack of HLA-compatible donors. The use of umbilical cord blood (UCB) permits transplantation of many patient
Externí odkaz:
https://doaj.org/article/755950a4c5214302be9eb8cac96b0847
Autor:
Erica J Di Pierro, Leonid S. Metelitsa, Rammurti T. Kamble, Tao Wang, Simon N. Robinson, Amy N. Courtney, Olga Dakhova, Premal Lulla, George Carrum, Carlos A. Ramos, Chunchao Zhang
Publikováno v:
Blood. 138:2819-2819
Autologous T cells engineered to express a CD19-specific chimeric antigen receptor (CAR) mediate high rates of complete response (CR) in patients with B-cell malignancies. However, autologous cell therapy products are time- and resource-intensive to
Autor:
Michael W. Thomas, Mark F. Munsell, Patrick A. Zweidler-McKay, Jeannie A. Javni, Elizabeth J. Shpall, Simon N. Robinson, Paul J. Simmons, Nathalie Brouard
Publikováno v:
Stem Cells and Development. 24:1066-1072
CD34(+) cell dose provides a measure of hematopoietic tissue that predicts the rate of engraftment upon transplant. It is positively correlated with multiple measures of hematopoietic recovery, including platelet engraftment. Here we identify a subpo
Macro optical projection tomography for large scale 3D imaging of plant structures and gene activity
Autor:
Karen Lee, Jacob L. Newman, Grant Calder, Christopher R. Hindle, Jerome Avondo, Simon N. Robinson, Enrico Coen
Publikováno v:
Journal of Experimental Botany
Highlight Macro OPT captures 3D morphologies of plants up to 60 mm by 45 mm, enabling visualisation of plant-insect interactions and gene activity.
Optical projection tomography (OPT) is a well-established method for visualising gene activity in
Optical projection tomography (OPT) is a well-established method for visualising gene activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58008d2de80792a98ac8743dccfede0
https://ueaeprints.uea.ac.uk/id/eprint/72632/
https://ueaeprints.uea.ac.uk/id/eprint/72632/
Autor:
Clara Bueno, Pablo Menendez, C. Fernández de Larrea, Elizabeth J. Shpall, N Shah, I Mc Niece, Amer Najjar, Simon N. Robinson, Michael W. Thomas, Eric Yvon, Alvaro Urbano-Ispizua, Beatriz Martín-Antonio, Robert Z. Orlowski, C. Muñoz-Pinedo, Claude Chew, S Li
Publikováno v:
Cell Death & Differentiation. 22:96-107
Natural killer cells (NK) are important effectors of anti-tumor immunity, activated either by the downregulation of HLA-I molecules on tumor cells and/or the interaction of NK-activating receptors with ligands that are overexpressed on target cells u
Autor:
Hong Yang, Jeannie A. Javni, Paul J. Simmons, Elizabeth J. Shpall, Michael W. Thomas, Simon N. Robinson, Junjun Lu, Patrick A. Zweidler-McKay
Publikováno v:
Cytotherapy.
Background aims Despite ethnic diversity and ready availability of cryopreserved, human leukocyte antigen–typed cord blood (CB), delayed engraftment remains a significant hurdle to successful CB transplantation. Suboptimal homing of CB hematopoieti
Autor:
Andras Heczey, Gianpietro Dotti, Ho Ngai, Amy N. Courtney, Leonid S. Metelitsa, Gengwen Tian, Simon N. Robinson
Publikováno v:
Cancer Immunology Research. 7:IA09-IA09
Due to their natural anti-tumor properties and ability to preferentially localize to the neuroblastoma (NB) tumor site, Vα24-invariant natural killer T cells (NKTs) are promising candidate immune effectors for chimeric antigen receptor (CAR)-based i