Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Simon N. Jacob"'
Autor:
Viktor M. Eisenkolb, Lisa M. Held, Alexander Utzschmid, Xiao-Xiong Lin, Sandro M. Krieg, Bernhard Meyer, Jens Gempt, Simon N. Jacob
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112467- (2023)
Summary: There are vast gaps in our understanding of the organization and operation of the human nervous system at the level of individual neurons and their networks. Here, we report reliable and robust acute multichannel recordings using planar micr
Externí odkaz:
https://doaj.org/article/6bc1950117ed4b9f98b7fd5abd378b8e
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Dopaminergic activity in prefrontal cortex is important for working memory but the neural mechanisms of its action are not known. Jacob and colleagues show that dopamine D1 receptors regulate neural responses to relevant stimuli in a cell-type-specif
Externí odkaz:
https://doaj.org/article/9dc27e6598744e7a8b81bdb3e0949ac6
Autor:
Simon N. Jacob, Hendrikje Nienborg
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
All neuronal circuits are subject to neuromodulation. Modulatory effects on neuronal processing and resulting behavioral changes are most commonly reported for higher order cognitive brain functions. Comparatively little is known about how neuromodul
Externí odkaz:
https://doaj.org/article/613046fba1194e3499af9f3a0a531365
Autor:
Ileana L. Hanganu-Opatz, Thomas Klausberger, Torfi Sigurdsson, Andreas Nieder, Simon N. Jacob, Marlene Bartos, Jonas-Frederic Sauer, Daniel Durstewitz, Christian Leibold, Ilka Diester
Publikováno v:
Neuron. 111:1020-1036
Autor:
Markus Ploner, Alena Buyx, Jens Gempt, Julijana Gjorgjieva, Ruth Müller, Josef Priller, Daniel Rückert, Bernhard Wolfrum, Simon N. Jacob
Publikováno v:
Nature Mental Health. 1:5-7
SummaryModern neuroscience has seen the rise of a population-doctrine that represents cognitive variables using geometrical structures in activity space. Representational geometry does not, however, account for how individual neurons implement these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65002d9eaa4ceb8db5a05ec5e991dfd
https://doi.org/10.1101/2023.03.06.531377
https://doi.org/10.1101/2023.03.06.531377
Autor:
Ajit Ranganath, Simon N. Jacob
Publikováno v:
The Neuroscientist. 22:593-603
The prefrontal cortex is the center of cognitive control. Processing in prefrontal cortical circuits enables us to direct attention to behaviorally relevant events; to memorize, structure, and categorize information; and to learn new concepts. The pr
Publikováno v:
Neuron. 99(3)
How is neuronal activity across distant brain regions orchestrated to allow multiple stimuli to be stored together in working memory, yet maintained separate for individual readout and protection from distractors? Using paired recordings in the prefr
Autor:
Simon N, Jacob, Hendrikje, Nienborg
Publikováno v:
Frontiers in Neural Circuits
All neuronal circuits are subject to neuromodulation. Modulatory effects on neuronal processing and resulting behavioral changes are most commonly reported for higher order cognitive brain functions. Comparatively little is known about how neuromodul
Autor:
Simon N. Jacob, Andreas Nieder
Publikováno v:
Neuron. 83:226-237
Summary Prefrontal cortex (PFC) and posterior parietal cortex are important for maintaining behaviorally relevant information in working memory. Here, we challenge the commonly held view that suppression of distractors by PFC neurons is the main mech