Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Simon Musyoka Mwangi"'
Autor:
Chunhua Yang, Simon Musyoka Mwangi, Arun Balasubramaniam, Ge Li, Olivier Merlin-Zhang, Yunshan Liu, Shanthi Srinivasan
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 1, Pp 38-47 (2024)
Background and Aims: The overexpression of glial cell-derived neurotrophic factor (GDNF) in the liver and adipose tissues offers strong protection against high-fat diet (HFD)-induced obesity in mice. We hypothesize that sustainably enhancing GDNF exp
Externí odkaz:
https://doaj.org/article/4daab42ba88946a0898b2872d81f2a92
Autor:
Arun Balasubramaniam, Ge Li, Anita Ramanathan, Simon Musyoka Mwangi, C. Michael Hart, Jack L. Arbiser, Shanthi Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Enteric neuron degeneration has been observed during aging, and in individuals with metabolic dysfunction including obesity and diabetes. Honokiol, a naturally occurring compound, is an activator of Sirtuin-3 (SIRT3) that has antioxidant act
Externí odkaz:
https://doaj.org/article/9f3ac1106c164679b78f7efd63352a3e
Autor:
Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A. Dawson, Young C. Jang, C. Michael Hart, Mark J. Czaja, Shanthi Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairme
Externí odkaz:
https://doaj.org/article/556901cf6394459b8308f062a92d5843
Autor:
Pavithra Chandramowlishwaran, Anitha Vijay, Daniel Abraham, Ge Li, Simon Musyoka Mwangi, Shanthi Srinivasan
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neurodegeneration of the central and enteric nervous systems is a common feature of aging and aging-related diseases, and is accelerated in individuals with metabolic dysfunction including obesity and diabetes. The molecular mechanisms of neurodegene
Externí odkaz:
https://doaj.org/article/f9208e46026d49b5b39bdf6c8a5766d1
Autor:
Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A. Dawson, Young C. Jang, C. Michael Hart, Mark J. Czaja, Shanthi Sriniva
Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06374d6362c4d06127dbd891530ee5e4
https://doi.org/10.21203/rs.3.rs-1677830/v1
https://doi.org/10.21203/rs.3.rs-1677830/v1
Publikováno v:
Veterinary Immunology and Immunopathology. 86:251-254
Tumor necrosis factor-alpha (TNF-alpha) is a key mediator of inflammatory responses and gram-negative bacterial sepsis, but the role that it plays during Salmonella enterica species bacterial infections in swine has not yet been elucidated. To facili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1c4d749c595be44abb525c8b74f0ae
https://doi.org/10.1016/s0165-2427(02)00034-x
https://doi.org/10.1016/s0165-2427(02)00034-x
Autor:
A. G. Andrianarivo, Cecilia Muriuki, Simon Musyoka Mwangi, Paul Muiya, Bea Mertens, Linda Logan-Henfrey
Publikováno v:
Veterinary Immunology and Immunopathology. 59:65-78
The cDNA coding for the soluble form of bovine stem cell factor (boSCFAla165) was cloned and recombinant protein was produced in bacteria as a histidine tagged-protein. The protein was purified from the inclusion bodies in one step by metal chelation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3f96f67ee3f2f9b107ef00e352ac31
https://doi.org/10.1016/s0165-2427(97)00068-8
https://doi.org/10.1016/s0165-2427(97)00068-8
Publikováno v:
Gene. 162(2)
Interleukin-3 (IL-3) is one of the cytokines that act during the early and late stages of blood cell formation. To enable the study of the role of IL-3 in bovine haemopoietic stem cell differentiation, the polymerase chain reaction was used to amplif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff91af858bb59bb9438fcb5ea2e82ee
https://pubmed.ncbi.nlm.nih.gov/7557449
https://pubmed.ncbi.nlm.nih.gov/7557449
Publikováno v:
Acta tropica. 59(4)
Changes in plasma iron and zinc concentration were studied in rabbits following a needle challenge with Trypanosoma brucei brucei clone ILTat 2.1. The infection resulted in a decrease of the concentration of both trace elements. Plasma iron concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dbb0afc98ab52f2d4b16fd76bd0b77
https://pubmed.ncbi.nlm.nih.gov/8533664
https://pubmed.ncbi.nlm.nih.gov/8533664