Ozone depletion in the Antarctic region triggers intense changes in sea salt geochemistry

Autor: Sérgio Gonçalves, Heitor Evangelista, Johannes Weis, Tristan Harder, Swarup China, Simon Muller, Magdalena Marques, Newton de Magalhães Neto, Heber Passos, Marcelo Sampaio, Jefferson Simões, Bruno Ximenes, Carlos Yamamoto, Alexander Laskin, Mary Gilles, Ricardo Godoi

The Antarctic environment has been used as a natural field laboratory to investigate the impacts of enhanced UV-B radiation over the polar terrestrial biota, marine life, and the cryosphere. UV-B increased levels occur due to the stratospheric ozone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c927a32004c63275fb30fc1144275aa
https://doi.org/10.21203/rs.3.rs-1882972/v1

Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient

Autor: Trine H. Mogensen, Kristian Alsbjerg Skipper, Martin K. Thomsen, Ensieh Farahani, Sofie E. Jørgensen, Alon Schneider Hait, Jacob Giehm Mikkelsen, Lise Kay, Søren R. Paludan, Mariane H. Schleimann, Johanna Heinz, Michelle M. Thomsen, Yujia Cai, Nanna-Sophie Brinck Andersen, Simon Muller Larsen

Publikováno v: Brinck Andersen, N S, Jørgensen, S E, Skipper, K A, Larsen, S M, Heinz, J, Thomsen, M M, Farahani, E, Cai, Y, Hait, A S, Kay, L, Giehm Mikkelsen, J, Høgsbjerg Schleimann, M, Thomsen, M K, Paludan, S R & Mogensen, T H 2021, ' Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient ', Autophagy, vol. 17, no. 9, pp. 2449-2464 . https://doi.org/10.1080/15548627.2020.1831800
Autophagy

Paralytic poliomyelitis is a rare disease manifestation following poliovirus (PV) infection. The disease determinants remain largely unknown. We used whole exome sequencing to uncover possible contributions of host genetics to the development of dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af82cd582d877d97ab3fc590191c99
https://pure.au.dk/portal/da/publications/essential-role-of-autophagy-in-restricting-poliovirus-infection-revealed-by-identification-of-an-atg7-defect-in-a-poliomyelitis-patient(a498e2fb-f7a9-4eb3-8c46-a0a229da79ab).html

Dermatology teaching for undergraduate medical students in clinical routine – a structured four-week curriculum

Autor: Tobias Kliesener, Madeleine Jandek, Alexander Navarini, Oliver Brandt, Simon Müller

Publikováno v: BMC Medical Education, Vol 24, Iss 1, Pp 1-13 (2024)

Abstract Background Dermatology teaching is fundamental for the promotion of young colleagues in our specialty. However, traditional teaching methods are being scrutinized by students of the ‘Generation Y and Z’, which can pose new challenges for

Externí odkaz: https://doaj.org/article/9cd11049601348ae9004038437e85bff

Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

Autor: Søren R. Paludan, Alon Schneider Hait, Sathya Darmalinggam, Mette Christiansen, Simon Muller Larsen, Jørgen Kjems, Darshana D. Kadekar, Kristina Eriksson, Serge Mostowy, Liviu Ionut Moldovan, Nanna-Sophie Brinck Andersen, Vanessa Sancho-Shimizu, Trine H. Mogensen, Lasse Sommer Kristensen, Isobel Parkes, David Olagnier, Marie Helleberg, Demi van der Horst, Michelle M. Thomsen, Mette Ratzer Freytag, Kristian Alsbjerg Skipper, Stine H. Rahbek, Jacob Giehm Mikkelsen, Christian Brandt, Chiranjeevi Bodda, Fanghui Ren

Publikováno v: Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Brinck Andersen, N-S, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2020, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science Immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/sciimmunol.abc2691
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Andersen, N S B, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2021, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/SCIIMMUNOL.ABC2691
Science Immunology

Recurrent herpesvirus infections can manifest in different forms of disease, including cold sores, genital herpes, and encephalitis. There is an incomplete understanding of the genetic and immunological factors conferring susceptibility to recurrent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e2d27ad827935f3a3c72318f2fa311
https://pure.au.dk/portal/da/publications/defects-in-lc3b2-and-atg4a-underlie-hsv2-meningitis-and-reveal-a-critical-role-for-autophagy-in-antiviral-defense-in-humans(660e28c6-e88f-4155-8813-69748e66d63d).html

Closing the Theory-Practice Gap: Psychologically-Based Laboratory Course in Electrical Engineering

Autor: Thorsten A. Brinkmann, Emily Wilbrand, Eike Osmers, Andreas R. Diewald, Simon Muller

Publikováno v: EDUCON

Psychology abounds in theory and empirical evidence about learning and teaching methods. Electrical engineering education however often lacks the application of this knowledge. In the following paper, Problem- and Project-Based-Learning will be exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::127b504e77225b4cd33793dd22fea867
https://doi.org/10.1109/educon45650.2020.9125398