Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simon Moule"'
Publikováno v:
British journal of haematology. 200(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9503a78b5456acb178193122d22e56c7
https://pubmed.ncbi.nlm.nih.gov/36190315
https://pubmed.ncbi.nlm.nih.gov/36190315
Autor:
Simon Moule, Ruth Clifford, Adam J. Mead, Michelle Rugless, Petter S. Woll, D Atkinson, Shirley Henderson, Anna Schuh, Nicola Bienz, Sten Eirik W. Jacobsen, James S. Wainscoat, Paresh Vyas
Abstract 1738 Since the initial description of V617F somatic mutation in patients with Philadelphia chromosome negative myeloproliferative neoplasms (MPNs), a remarkable association between alterations in the JAK2 gene and MPNs has emerged. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b034e86919a36d0925b6caf2016f5d25
https://ora.ox.ac.uk/objects/uuid:e50e82ac-2ead-4101-b5f6-fdc100960634
https://ora.ox.ac.uk/objects/uuid:e50e82ac-2ead-4101-b5f6-fdc100960634
Autor:
R Clifford, Sten Eirik W. Jacobsen, Simon Moule, Alexandra Dusa, Adam Burns, Shirley Henderson, Nicholas C.P. Cross, Petter S. Woll, Rosemary E. Gale, Michelle Rugless, Paresh Vyas, Stefan N. Constantinescu, Nicola Bienz, Adam J. Mead, Joannah Score, Deborah Atkinson, Christian Pecquet, Onima Chowdhury, Anna Schuh
Publikováno v:
Blood. 121(20)
The association between somatic JAK2 mutation and myeloproliferative neoplasms (MPNs) is now well established. However, because JAK2 mutations are associated with heterogeneous clinical phenotypes and often occur as secondary genetic events, some asp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5e39c5573aa309dfdd759cf6aee679
http://ora.ox.ac.uk/objects/uuid:2d21ab33-f03b-4d0c-8eeb-f20aa678bf87
http://ora.ox.ac.uk/objects/uuid:2d21ab33-f03b-4d0c-8eeb-f20aa678bf87
Publikováno v:
New England Journal of Medicine. 369:197-198
Ruxolitinib blocks Janus kinase (JAK) 1 and 2 signaling, a pathway involved in host defenses. A case is reported in which progressive multifocal leukoencephalopathy developed in a 75-year-old man with myelofibrosis a few weeks after the initiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bbb35032c10271d307bbdcd3688d524
https://doi.org/10.1056/nejmc1302135
https://doi.org/10.1056/nejmc1302135