Zobrazeno 1 - 10
of 478
pro vyhledávání: '"Simon Ming-Yuen Lee"'
Autor:
Jingjing Li, Xi Luo, Polly Ho-Ting Shiu, Yanfen Cheng, Xin Nie, Panthakarn Rangsinth, Benson Wui Man Lau, Chengwen Zheng, Xuebo Li, Renkai Li, Simon Ming-Yuen Lee, Chaomei Fu, Sai-Wang Seto, Jinming Zhang, George Pak-Heng Leung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116901- (2024)
Background: Amauroderma rugosum (AR) is a medicinal mushroom commonly used to treat inflammation, gastric disorders, epilepsy, and cancers due to its remarkable anti-inflammatory and anti-oxidative properties. This study was designed to evaluate the
Externí odkaz:
https://doaj.org/article/7e656c19a7834c56827b62e855fd51da
Autor:
Qian Chen, Nan Xu, Chen Zhao, Yulin He, Sandy Hio Tong Kam, Xue Wu, Pan Huang, Min Yang, Clarence Tsun Ting Wong, Gandhi Radis-Baptista, Benqin Tang, Guangyi Fan, Guiyi Gong, Simon Ming-Yuen Lee
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107173- (2024)
Our recent multi-omics studies have revealed rich sources of novel bioactive proteins and polypeptides from marine organisms including cnidarians. In the present study, we initially conducted a transcriptomic analysis to review the composition profil
Externí odkaz:
https://doaj.org/article/5d245205ef8542c7b83eeac34f6d4a4a
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103057- (2024)
Neuroinflammation and oxidative stress play a crucial role in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease. The triggering receptor expressed on myeloid cells 2 (TREM2), highly expressed by microglia in the central
Externí odkaz:
https://doaj.org/article/38fb32f2b5964f0d9139139a232b5b54
Autor:
Jingjing Li, Zhuyun Liu, Xiaoping Wu, Simon Ming-Yuen Lee, Sai-Wang Seto, Jinming Zhang, Guo-Chun Zhou, George Pak-Heng Leung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116269- (2024)
AGS-30, a new andrographolide derivative, showed significant anticancer and anti-angiogenic characteristics. However, its role in controlling macrophage polarization and tumor immune response is unknown. Thus, the main goals of this study are to inve
Externí odkaz:
https://doaj.org/article/fecc3371e7024c1d83c259e371e20b6e
Autor:
Qian Liu, Vsevolod Telezhkin, Wenkai Jiang, Yu Gu, Yan Wang, Wei Hong, Weiming Tian, Polina Yarova, Gaofeng Zhang, Simon Ming-yuen Lee, Peng Zhang, Min Zhao, Nicholas D. Allen, Emilio Hirsch, Josef Penninger, Bing Song
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background Neural stem cells (NSCs) are considered as candidates for cell replacement therapy in many neurological disorders. However, the propensity for their differentiation to proceed more glial rather than neuronal phenotypes in patholog
Externí odkaz:
https://doaj.org/article/797ccd32264d468c927a159ef5755817
Autor:
Yuan-Ye Dang, Hua Luo, Yong-Mei Li, Yang Zhou, Xiu Luo, Shui-Mu Lin, Shou-Ping Liu, Simon Ming-Yuen Lee, Chu-Wen Li, Xiao-Yan Dai
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-22 (2021)
Abstract Background Arsenic (As3+) is a carcinogen with considerable environmental and occupational relevancy. Its mechanism of action and methods of prevention remain to be investigated. Previous studies have demonstrated that ROS is responsible for
Externí odkaz:
https://doaj.org/article/c2749398cbd344599758fae56f684e94
Autor:
Adrianna Skiba, Daniele Pellegata, Veronika Morozova, Ewelina Kozioł, Barbara Budzyńska, Simon Ming-Yuen Lee, Jürg Gertsch, Krystyna Skalicka-Woźniak
Publikováno v:
Cells, Vol 12, Iss 11, p 1540 (2023)
Zebrafish (Danio rerio) assays provide a versatile pharmacological platform to test compounds on a wide range of behaviors in a whole organism. A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of b
Externí odkaz:
https://doaj.org/article/54c9053e75814ac5bd2bfd79806650c1
Autor:
Gabriel Hoi-Huen Chan, Enoch Chan, Carsten Tsun-Ka Kwok, George Pak-Heng Leung, Simon Ming-Yuen Lee, Sai-Wang Seto
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ageing is a risk factor for many degenerative diseases. Cardiovascular diseases (CVDs) are usually big burdens for elderly, caregivers and the health system. During the aging process, normal functions of vascular cells and tissue progressively lost a
Externí odkaz:
https://doaj.org/article/1870e783e08d4239968713a32f9c7980
Autor:
Jingjing Li, Renkai Li, Xiaoping Wu, Chengwen Zheng, Polly Ho-Ting Shiu, Panthakarn Rangsinth, Simon Ming-Yuen Lee, George Pak-Heng Leung
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Angiogenesis, the formation of new capillaries from pre-existing vascular networks, plays an important role in many physiological and pathological processes. The use of pro-angiogenic agents has been proposed as an attractive approach for promoting w
Externí odkaz:
https://doaj.org/article/8901e56df68e4245b1452c98a9ea26d8
Autor:
Qingping Lan, Zhitao Ren, Yan Chen, Guozhen Cui, I. Cheong Choi, Carolina Oi Lam Ung, Hon Ho Yu, Simon Ming-Yuen Lee
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional Chinese medicine formula such as Qushihuayu (QSHY) composing of
Externí odkaz:
https://doaj.org/article/8c28a3105b294b3fbfde88b6045722f7