Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Simon Mathien"'
Autor:
Martin Cottet, Yuniel Fernandez Marrero, Simon Mathien, Karine Audette, Raphaelle Lambert, Eric Bonneil, Kenneth Chng, Alex Campos, David W. Andrews
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100121- (2024)
High-content imaging approaches, in combination with the use of perturbing agents such as small molecules or CRISPR-driven gene editing, have widely contributed to the identification of new therapeutic compounds. Thanks to recent advances in image-an
Externí odkaz:
https://doaj.org/article/5564449d6c78415e9c5915e263f7b2df
Autor:
Miriam Marquis, Salix Boulet, Simon Mathien, Justine Rousseau, Paméla Thébault, Jean-François Daudelin, Julie Rooney, Benjamin Turgeon, Claudine Beauchamp, Sylvain Meloche, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86681 (2014)
The classical mitogen-activated protein kinases (MAPKs) ERK1 and ERK2 are activated upon stimulation of cells with a broad range of extracellular signals (including antigens) allowing cellular responses to occur. ERK3 is an atypical member of the MAP
Externí odkaz:
https://doaj.org/article/bf49f1204adc4e9a90c201b2691e7067
Autor:
Hellen Kuasne, Anne-Marie fortier, Sandrine Busque, Simon Mathien, Paul Savage, Constanza Martinez Ramirez, Anie Monast, Margarita Soleinova, Atilla Omeroglu, Jamil Asselah, Nathaniel Bouganim, Sarkis Meterissian, Mark Basik, Morag Park
Publikováno v:
Cancer Research. 83:P3-08
Invasive breast carcinoma is a combination of heterogeneous diseases with distinct molecular and clinical features. Some subsets of breast cancer present major clinical challenges, including triple-negative, metastatic/recurrent disease and rare brea
Publikováno v:
Pharmacological Reviews. 73:1434-1467
Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling pathways that play essential roles in transducing extracellular environmental signals into diverse cellular responses to maintain homeostasis. These pathways are
Autor:
Benjamin Turgeon, Sonia Klinger, Philippe Coulombe, Marc K. Saba-El-Leil, Sylvain Meloche, Kim Lévesque, Simon Mathien, Justine Rousseau, Mathilde Soulez
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2019, 39 (6), ⟨10.1128/MCB.00527-18⟩
Molecular and Cellular Biology, American Society for Microbiology, 2019, 39 (6), ⟨10.1128/MCB.00527-18⟩
The physiological functions of the atypical mitogen-activated protein kinase extracellular signal-regulated kinase 3 (ERK3) remain poorly characterized. Previous analysis of mice with a targeted insertion of the lacZ reporter in the Mapk6 locus (Mapk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd306337ab0590240fc5f9d29f5c646
https://hal.archives-ouvertes.fr/hal-03101787
https://hal.archives-ouvertes.fr/hal-03101787
Autor:
Philippe Coulombe, Sylvain Meloche, Benjamin Turgeon, Marc K. Saba-El-Leil, Sonia Klinger, Mathilde Soulez, Justine Rousseau, Kim Lévesque, Simon Mathien
The physiological functions of the atypical MAP kinase ERK3 remain poorly characterized. Previous analysis of mice with a targeted insertion of the lacZ reporter in the Mapk6 locus (Mapk6lacZ) showed that inactivation of ERK3 in Mapk6lacZ mice leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0885f720ef6c631e5323a0c3f26976b2
Autor:
Simon Mathien, Sylvain Meloche
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Autor:
Simon Mathien, Sylvain Meloche
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on MAPK6 (mitogen-activated protein kinase 6), with data on DNA, on the protein encoded, and where the gene is implicated.
Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein kinase (MAPK) whose regulatory mechanisms and biological functions remain superficially understood. Contrary to most protein kinases, ERK3 is a highly unstable pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eca127f68c3fd299e6ed85dbd260d10
https://europepmc.org/articles/PMC5394282/
https://europepmc.org/articles/PMC5394282/