Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Simon Maechling"'
Autor:
Stephen D. Lindell, Thomas Petry, Lisa Blanazs, Susanne Haupt, Simon Maechling, Merisa Leonhardt, Jörg Freigang, Richard L. Sabina, Robert Klein, Bernd Laber
Publikováno v:
Bioorganic & Medicinal Chemistry. 43:116272
Inhibitors of the enzyme adenosine monophosphate deaminase (AMPD) show interesting levels of herbicidal activity. An enzyme mechanism-based approach has been used to design new inhibitors of AMPD starting from nebularine (6) and resulting in the synt
Publikováno v:
ACS Medicinal Chemistry Letters. 1:286-289
C-Ribosyl imidazo[2,1-f][1,2,4]triazines and 3-[2-(3-carboxyphenyl)ethyl]-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ols represent two classes of known AMP deaminase inhibitors. A combination of the aglycone from the former class with the ribose
Publikováno v:
Tetrahedron. 63:7112-7119
Olefin cross metathesis of vinyl pyrrolidine derivatives has been explored, culminating in a concise synthesis of (+)-7a- epi -7-deoxycasuarine in nine steps, from commercially available starting materials.
Publikováno v:
Journal of Organometallic Chemistry. 691:5267-5277
The synthesis of new ruthenium-based catalysts applicable for both homogeneous and heterogeneous metathesis is described. Starting from the Hoveyda-Grubbs first generation ( 1 ) and the Hoveyda-Grubbs second generation ( 2 ) catalysts the homogeneous
Publikováno v:
Tetrahedron Letters. 47:8617-8620
The synthesis and characterisation of a new highly active Hoveyda–Grubbs 2nd generation type catalyst is described. Substitution of one chloride ligand with a partially fluorinated trialkoxysilyl substituted carboxylate leads to the stable monocarb
Publikováno v:
Angewandte Chemie. 118:1933-1937
Publikováno v:
Organometallics. 25:25-28
The facile synthesis of two new unsymmetrical N-heterocyclic carbene (NHC) ligands from commercially available monosubstituted diamines is presented. The resultant unsymmetrical NHC ligands have been complexed to ruthenium to give novel olefin metath
Publikováno v:
Advanced Synthesis & Catalysis. 347:1413-1422
A turnover number (TON) study of ruthenium-based metathesis catalysts has been conducted for ring-closing metathesis (RCM) in dilute solution. Unexpectedly the results indicate that 1 s t generation metathesis catalysts can give higher TON in RCM of
Publikováno v:
Journal of combinatorial chemistry. 12(6)
Autor:
Stephen D. Lindell, Simon Maechling
Publikováno v:
ChemInform. 39