Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simon M. Brooke"'
Autor:
Arthur Christopoulos, Colin Molloy, Michael D. Crabtree, Simon M. Brooke, Christoffer Bundgaard, Adrian J. Mogg, Patrick M. Sexton, Helen E. Sanger, Karen J. Thompson, Sophie J. Bradley, Christian C. Felder, Andrew B. Tobin, Christopher J. Langmead, Lisa M. Broad, Louis Dwomoh
Publikováno v:
Molecular Pharmacology. 93:645-656
The realization of the therapeutic potential of targeting the M1 muscarinic acetylcholine receptor (mAChR) for the treatment of cognitive decline in Alzheimer’s disease has prompted the discovery of M1 mAChR ligands showing efficacy in alleviating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e4008c1543e1e5e40a2a7a21ba0475a
https://doi.org/10.1124/mol.118.111872
https://doi.org/10.1124/mol.118.111872
Autor:
Sophie J, Bradley, Colin, Molloy, Christoffer, Bundgaard, Adrian J, Mogg, Karen J, Thompson, Louis, Dwomoh, Helen E, Sanger, Michael D, Crabtree, Simon M, Brooke, Patrick M, Sexton, Christian C, Felder, Arthur, Christopoulos, Lisa M, Broad, Andrew B, Tobin, Christopher J, Langmead
Publikováno v:
Molecular Pharmacology
The realization of the therapeutic potential of targeting the M1 muscarinic acetylcholine receptor (mAChR) for the treatment of cognitive decline in Alzheimer’s disease has prompted the discovery of M1 mAChR ligands showing efficacy in alleviating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53c63447ffaed7a256dbd47cdf0c741d
https://pubmed.ncbi.nlm.nih.gov/29695609
https://pubmed.ncbi.nlm.nih.gov/29695609
Autor:
Adrian J. Butcher, Simon M. Brooke, Adrian J. Mogg, Jennifer M. Edwards, Rudi Prihandoko, Julie-Myrtille Bourgognon, Andrew R. Bottrill, Sophie J. Bradley, Christian C. Felder, Andrew B. Tobin, Lisa M. Broad, R. A. John Challiss, Timothy Macedo-Hatch
Publikováno v:
The Journal of Biological Chemistry
Establishing the in vivo activation status of G protein-coupled receptors would not only indicate physiological roles of G protein-coupled receptors but would also aid drug discovery by establishing drug/receptor engagement. Here, we develop a phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267661159099c767f293cee6b40d99fc
https://pubmed.ncbi.nlm.nih.gov/26826123
https://pubmed.ncbi.nlm.nih.gov/26826123
Autor:
Andrew B. Tobin, Simon M. Brooke
Publikováno v:
Toxicology Letters. 229:S41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4d0d053b679d6c24273ca5c76886a8b
https://doi.org/10.1016/j.toxlet.2014.06.183
https://doi.org/10.1016/j.toxlet.2014.06.183