Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Simon M. Bone"'
Publikováno v:
Diagnostic microbiology and infectious disease. 99(2)
This study compares the performance of a commercial polymerase chain reaction (PCR) assay for detection of herpes simplex virus (HSV) 1 and 2, varicella zoster virus (VZV), and Treponema pallidum with laboratory-developed assays. A panel of 250 sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6472a1984598bd1c9218e9fd6e29f136
https://pubmed.ncbi.nlm.nih.gov/33176262
https://pubmed.ncbi.nlm.nih.gov/33176262
Publikováno v:
Biosensors and Bioelectronics. 70:330-337
We have created molecular switches that consist of nucleic-acid cleaving DNAzymes which are temporarily inactivated by hybridization with blocking oligonucleotides. The unique design of the switches offers significant advantages over existing methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3ef4b84dc642e9c34c4569cbf875c4
https://doi.org/10.1016/j.bios.2015.03.057
https://doi.org/10.1016/j.bios.2015.03.057
Publikováno v:
Analytical Chemistry. 86:9106-9113
Diagnostic tests performed in the field or at the site of patient care would benefit from using a combination of inexpensive, stable chemical reagents and simple instrumentation. Here, we have developed a universal "DNA-only Cascade" (DoC) to quantit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c87e7bf72d3b90624ea4d494ed55b2
https://doi.org/10.1021/ac501811r
https://doi.org/10.1021/ac501811r
Publikováno v:
Journal of the American Chemical Society
To increase the versatility and utility of nucleic acid enzymes, we developed multicomponent complexes, known as MNAzymes, which produce amplified "output" signals in response to specific "input" signals. Multiple oligonucleotide partzymes assemble i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73e7ab8aff7ddd4e571732ae0b5a70e
http://europepmc.org/articles/PMC2808728
http://europepmc.org/articles/PMC2808728
Autor:
Simon M. Bone, Alison V. Todd
Publikováno v:
Chemical communications (Cambridge, England). 50(87)
Novel methods were developed to isothermally detect target nucleic acids and initiate signal amplification cascades. The methods utilize target-specific MNAzymes to activate universal primer molecules. These primers can subsequently promote the auton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a69487644d98d3b6627608826abc19
https://pubmed.ncbi.nlm.nih.gov/25227474
https://pubmed.ncbi.nlm.nih.gov/25227474
Autor:
Mark D. Spanevello, Timothy J. Molloy, Trina Yeadon, Jeff Holst, Gordon F. Burns, Kristy L. Shipman, D M Campbell, Lisa F. Lincz, Alireza Ardjmand, Rick F. Thorne, G Nelmes, Daniel M. Johnstone, C E de Bock, Andrew W. Boyd, Daniel Catchpoole, Simon M. Bone
Publikováno v:
Leukemia. 26(5)
Improved survival of patients with acute lymphoblastic leukemia (ALL) has emerged from identifying new prognostic markers; however, 20% of children still suffer recurrence. Previously, the altered expression of Fat1 cadherin has been implicated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60713460bbc9056f6562e4aa8325e0d1
https://pubmed.ncbi.nlm.nih.gov/22116550
https://pubmed.ncbi.nlm.nih.gov/22116550
Publikováno v:
ChemInform. 41
To increase the versatility and utility of nucleic acid enzymes, we developed multicomponent complexes, known as MNAzymes, which produce amplified "output" signals in response to specific "input" signals. Multiple oligonucleotide partzymes assemble i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c61eb3e1658f997f2979a8ef7a8f5703
https://doi.org/10.1002/chin.201020186
https://doi.org/10.1002/chin.201020186
Autor:
Lisa F. Lincz, Daniel M. Campbell, Rick F. Thorne, Andrew W. Boyd, Daniel Catchpoole, Timothy J. Molloy, Trina Yeadon, Gordon F. Burns, Jeff Holst, Kristy L. Shipman, Charles E. de Bock, Mark D. Spanevello, Daniel M. Johnstone, Simon M. Bone, Alireza Ardjmand
Publikováno v:
Clinical Biochemistry. 44:S71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb8c9f10b40863fb95f9c6b48cef7c3
https://doi.org/10.1016/j.clinbiochem.2011.08.154
https://doi.org/10.1016/j.clinbiochem.2011.08.154