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Akademický článek
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Autor:
Simon Lennard Schumann, Simon Kotnig, Yury Kutin, Maria Drosou, Lukas Stratmann, Yana Streltsova, Alexander Schnegg, Dimitrios Pantazis, Guido Clever, Müge Kasanmascheff
DNA G-quadruplexes (GQs) are of great interest due to their involvement in crucial biological processes such as telomerase maintenance and gene expression. Furthermore, they are reported as catalytically active DNAzymes and building blocks in bio-nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c9407d27389c3e7d743730a7822e6b0
https://doi.org/10.26434/chemrxiv-2023-kvfpw
https://doi.org/10.26434/chemrxiv-2023-kvfpw
Autor:
Mark J. Anderton, Anthony Johnson, Menelas N. Pangalos, Paul Morgan, David J. Nicholls, Stefan Platz, Ulf G. Eriksson, J. Carl Barrett, Jerome T. Mettetal, Ruth March, Mark Fidock, Dean G. Brown, James Matcham, Steve Rees, Michael A. Snowden, Simon Lennard, Bengt Hamrén
Publikováno v:
Nature Reviews Drug Discovery. 17:167-181
In 2011, AstraZeneca embarked on a major revision of its research and development (R&D) strategy with the aim of improving R&D productivity, which was below industry averages in 2005-2010. A cornerstone of the revised strategy was to focus decision-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5274ed67c97a44f4e83ae49c318d880
https://doi.org/10.1038/nrd.2017.244
https://doi.org/10.1038/nrd.2017.244
Autor:
Simon, Lennard
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df71ca16965de3ac28f70ac48c435ed7
https://pubmed.ncbi.nlm.nih.gov/11968510
https://pubmed.ncbi.nlm.nih.gov/11968510
Publikováno v:
Antibody Engineering ISBN: 9783540413547
The phage display of antibody fragments as Fabs or scFvs (McCafferty et al., 1990), has its origins in experiments demonstrating that both small peptides and folded proteins could be displayed on the surface of filamentous bacteriophage (Smith, 1985;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43eabe2bd1db01fe8869584c3e3d8533
https://doi.org/10.1007/978-3-662-04605-0_6
https://doi.org/10.1007/978-3-662-04605-0_6