Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Simon L.I.J. Denil"'
Autor:
Crystal Y. Chia, Pedro Madrigal, Simon L.I.J. Denil, Iker Martinez, Jose Garcia-Bernardo, Ranna El-Khairi, Mariya Chhatriwala, Maggie H. Shepherd, Andrew T. Hattersley, N. Ray Dunn, Ludovic Vallier
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 57-70 (2019)
Summary: Heterozygous de novo mutations in GATA6 are the most frequent cause of pancreatic agenesis in humans. In mice, however, a similar phenotype requires the biallelic loss of Gata6 and its paralog Gata4. To elaborate the human-specific requireme
Externí odkaz:
https://doaj.org/article/85ca6c716044458090cd3f3f8849497e
Autor:
Jamie Trott, Ee Kim Tan, Sheena Ong, Drew M. Titmarsh, Simon L.I.J. Denil, Maybelline Giam, Cheng Kit Wong, Jiaxu Wang, Mohammad Shboul, Michelle Eio, Justin Cooper-White, Simon M. Cool, Giulia Rancati, Lawrence W. Stanton, Bruno Reversade, N. Ray Dunn
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable v
Externí odkaz:
https://doaj.org/article/420b4b50331549cead36ed5ee5db165a