Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Simon L. Wuest"'
Autor:
Jenny Graf, Herbert Schulz, Markus Wehland, Thomas J. Corydon, Jayashree Sahana, Fatima Abdelfattah, Simon L. Wuest, Marcel Egli, Marcus Krüger, Armin Kraus, Petra M. Wise, Manfred Infanger, Daniela Grimm
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 926 (2024)
Cancer is defined as a group of diseases characterized by abnormal cell growth, expansion, and progression with metastasis. Various signaling pathways are involved in its development. Malignant tumors exhibit a high morbidity and mortality. Cancer re
Externí odkaz:
https://doaj.org/article/445a8a00015a428290f0ed9b9eeabf1a
Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine
Autor:
José Luis Cortés-Sánchez, Daniela Melnik, Viviann Sandt, Stefan Kahlert, Shannon Marchal, Ian R. D. Johnson, Marco Calvaruso, Christian Liemersdorf, Simon L. Wuest, Daniela Grimm, Marcus Krüger
Publikováno v:
Cells, Vol 12, Iss 22, p 2665 (2023)
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ a random positioning machi
Externí odkaz:
https://doaj.org/article/0f32450df8c24fc0ae9d647013e8627a
Autor:
Andreas Hammer, Geraldine Cerretti, Dario A. Ricciardi, David Schiffmann, Simon Maranda, Raphael Kummer, Christoph Zumbühl, Karin F. Rattenbacher-Kiser, Silvan von Arx, Sebastian Ammann, Frederic Strobl, Rayene Berkane, Alexandra Stolz, Ernst H. K. Stelzer, Marcel Egli, Enrico Schleiff, Simon L. Wuest, Maik Böhmer
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 138 (2022)
Calcium (Ca2+) elevation is an essential secondary messenger in many cellular processes, including disease progression and adaptation to external stimuli, e.g., gravitational load. Therefore, mapping and quantifying Ca2+ signaling with a high spatiot
Externí odkaz:
https://doaj.org/article/20eed5d6622e47309604c2af82478b5c
Autor:
Simon L. Wuest, Martina Caliò, Timon Wernas, Samuel Tanner, Christina Giger-Lange, Fabienne Wyss, Fabian Ille, Benjamin Gantenbein, Marcel Egli
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1289 (2018)
Due to the limited self-repair capacity of articular cartilage, the surgical restoration of defective cartilage remains a major clinical challenge. The cell-based approach, which is known as autologous chondrocyte transplantation (ACT), has limited s
Externí odkaz:
https://doaj.org/article/da653bc284934c93adddb37170bd8c46
Autor:
Simon L. Wuest, Geraldine Cerretti, Jennifer Louise Wadsworth, Cindy Follonier, Karin F. Rattenbacher-Kiser, Timothy Bradley, Marcel Egli, Fabian Ille
Publikováno v:
Acta Astronautica. 193:287-302
Autor:
Böhmer, Andreas Hammer, Geraldine Cerretti, Dario A. Ricciardi, David Schiffmann, Simon Maranda, Raphael Kummer, Christoph Zumbühl, Karin F. Rattenbacher-Kiser, Silvan von Arx, Sebastian Ammann, Frederic Strobl, Rayene Berkane, Alexandra Stolz, Ernst H. K. Stelzer, Marcel Egli, Enrico Schleiff, Simon L. Wuest, Maik
Publikováno v:
Biomedicines; Volume 10; Issue 1; Pages: 138
Calcium (Ca2+) elevation is an essential secondary messenger in many cellular processes, including disease progression and adaptation to external stimuli, e.g., gravitational load. Therefore, mapping and quantifying Ca2+ signaling with a high spatiot
Autor:
Monica Zocchi, Fabian Ille, Carsten Haack, Simon L. Wuest, Christina Giger-Lange, Jeanette A.M. Maier, Alessandra Cazzaniga, Marcel Egli, Adrian Koller, Sara Castiglioni
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8908, p 8908 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8908, p 8908 (2020)
We introduce a new benchtop microgravity simulator (MGS) that is scalable and easy to use. Its working principle is similar to that of random positioning machines (RPM), commonly used in research laboratories and regarded as one of the gold standards
Autor:
Fabian Ille, Marcel Egli, Martina Caliò, Geraldine Cerretti, G. S. Székely, Karin Rattenbacher-Kiser, Christian Jost, Cindy Follonier, Simon L. Wuest, Christoph Zumbuhl, Sarah Gander, Christina Giger-Lange, Jaro Arnold, Othmar Schälli
Adequate mechanical stimulation is essential for cellular health and tissue maintenance, including articular cartilage, which lines the articulating bones in joints. Chondrocytes, which are the sole cells found in articular cartilage, are responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5cbf7c4aff721ba5832830815434ce
Publikováno v:
Acta Astronautica. 141:228-236
Mechanical unloading by microgravity (or weightlessness) conditions triggers profound adaptation processes at the cellular and organ levels. Among other mechanisms, mechanosensitive ion channels are thought to play a key role in allowing cells to tra
Autor:
Jack J. W. A. van Loon, Thu Jennifer Ngo Anh, Marcel Egli, Peter C. M. Christianen, Sonja Brungs, Ruth Hemmersbach, Simon L. Wuest
Publikováno v:
Brungs, S, Egli, M, Wuest, S L, Christianen, P C M, van Loon, J J W A, Ahn, T J N & Hemmersbach, R 2016, ' Facilities for simulation of microgravity in the ESA ground-based facility programme ', Microgravity Science and Technology, vol. 28, no. 3, pp. 191-203 . https://doi.org/10.1007/s12217-015-9471-8
Microgravity Science and Technology, 28, 3, pp. 191-203
Brungs, S, Egli, M, Wuest, S L, Christianen, P C M, van Loon, J J W A, Thu Jennifer Ngo Anh & Hemmersbach, R 2016, ' Facilities for Simulation of Microgravity in the ESA Ground-Based Facility Programme ', Microgravity Science and Technology, vol. 28, no. 3, pp. 191-203 . https://doi.org/10.1007/s12217-015-9471-8
Microgravity Science and Technology, 28(3), 191-203. Springer Netherlands
Microgravity Science and Technology, 28, 191-203
Microgravity Science and Technology, 28, 3, pp. 191-203
Brungs, S, Egli, M, Wuest, S L, Christianen, P C M, van Loon, J J W A, Thu Jennifer Ngo Anh & Hemmersbach, R 2016, ' Facilities for Simulation of Microgravity in the ESA Ground-Based Facility Programme ', Microgravity Science and Technology, vol. 28, no. 3, pp. 191-203 . https://doi.org/10.1007/s12217-015-9471-8
Microgravity Science and Technology, 28(3), 191-203. Springer Netherlands
Microgravity Science and Technology, 28, 191-203
Knowledge of the role of gravity in fundamental biological processes and, consequently, the impact of exposure to microgravity conditions provide insight into the basics of the development of life as well as enabling long-term space exploration missi