Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Simon L. Dove"'
Autor:
Jennifer M. Peña, Samantha M. Prezioso, Kirsty A. McFarland, Tracy K. Kambara, Kathryn M. Ramsey, Padraig Deighan, Simon L. Dove
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In Pseudomonas aeruginosa, the protein AlpA activates the expression of the alp locus in response to DNA damage, leading to lysis in a subset of cells and enhancing virulence of other, surviving cells. Here, the authors show that AlpA acts as an anti
Externí odkaz:
https://doaj.org/article/b438ab3975a44616a29582404e1b10c2
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Adaptation of group A Streptococcus (GAS) to its human host is mediated by two-component systems that transduce external stimuli to regulate bacterial physiology. Among such systems, CsrRS (also known as CovRS) is the most extensively charac
Externí odkaz:
https://doaj.org/article/dd3673ad85fd473f988ceff06545bb13
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1543-1552 (2018)
Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions o
Externí odkaz:
https://doaj.org/article/1a2abea4d9c442e9826dcaf3e3e129c2
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT The orphan regulator RocA plays a critical role in the colonization and pathogenesis of the obligate human pathogen group A Streptococcus. Despite multiple lines of evidence supporting a role for RocA as an auxiliary regulator of the control
Externí odkaz:
https://doaj.org/article/3b252973b25c4b33b4e9c9a6e7a86e3d
Autor:
S.L. Rajasekhar Karna, Xhavit Zogaj, Jeffrey R. Barker, Janakiram Seshu, Simon L. Dove, Karl E. Klose
Publikováno v:
BioTechniques, Vol 49, Iss 5, Pp 831-833 (2010)
Comprehensive clone sets representing the entire genome now exist for a large number of organisms. The Gateway entry clone sets are a particularly useful means to study gene function, given the ease of introduction into any Gateway-suitable destinati
Externí odkaz:
https://doaj.org/article/b8fee9a36d92490e90761d0f02630ad3
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248201 (2021)
Streptococcus pyogenes or group A Streptococcus (GAS) is a leading cause of bacterial pharyngitis, skin and soft tissue infections, life-threatening invasive infections, and the post-infectious autoimmune syndromes of acute rheumatic fever and post-s
Externí odkaz:
https://doaj.org/article/26dda6ea80d34d66a6acb842aa6c8c58
Autor:
Kathryn M Ramsey, Hannah E Ledvina, Tenayaann M Tresko, Jamie M Wandzilak, Catherine A Tower, Thomas Tallo, Caroline E Schramm, S Brook Peterson, Shawn J Skerrett, Joseph D Mougous, Simon L Dove
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008566 (2020)
Host-derived glutathione (GSH) is an essential source of cysteine for the intracellular pathogen Francisella tularensis. In a comprehensive transposon insertion sequencing screen, we identified several F. tularensis genes that play central and previo
Externí odkaz:
https://doaj.org/article/4fb8a5aa854c48928b939a0b7ad93584
Autor:
Michael J. Gebhardt, Elizabeth A. Farland, Pallabi Basu, Keven Macareno, Sahar Melamed, Simon L. Dove
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA targets. In the gram-negative opportunistic pathogen Pseudomonas aeruginosa , over a hundred pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a468f99ced2d322055953fcb9e0b04b
https://doi.org/10.1073/pnas.2218407120
https://doi.org/10.1073/pnas.2218407120
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(46)
Although the mechanism by which the cyclic AMP receptor protein (CRP) regulates global gene transcription has been intensively studied for decades, new discoveries remain to be made. Here, we report that, during rapid growth, CRP associates with both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05acc4f136e677403d5f0230a3535ddf
https://pubmed.ncbi.nlm.nih.gov/36343262
https://pubmed.ncbi.nlm.nih.gov/36343262
Autor:
Yaxi Wang, Hannah E. Ledvina, Catherine A. Tower, Stanimir Kambarev, Elizabeth Liu, James C. Charity, Lieselotte S.M. Kreuk, Qiwen Chen, Larry A. Gallagher, Matthew C. Radey, Guilhem F. Rerolle, Yaqiao Li, Kelsi M. Penewit, Serdar Turkarslan, Shawn J. Skerrett, Stephen J. Salipante, Nitin S. Baliga, Joshua J. Woodward, Simon L. Dove, S. Brook Peterson, Jean Celli, Joseph D. Mougous
Glutathione (GSH) is an abundant metabolite that can act as a signal, a nutrient source, or serve in a redox capacity for intracellular pathogens. For Francisella, GSH is thought to be a critical in vivo source of cysteine; however, the cellular path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122a832db15a611c18edbe66c6192ce2
https://doi.org/10.1101/2023.02.02.526638
https://doi.org/10.1101/2023.02.02.526638
