Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Simon Kwoon‐Ho Chow"'
Autor:
Ning Zhang, Liting Zhai, Ronald Man Yeung Wong, Can Cui, Sheung-Wai Law, Simon Kwoon-Ho Chow, Stuart B. Goodman, Wing-Hoi Cheung
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Sarcopenia is a complex age-associated syndrome of progressive loss of muscle mass and strength. Although this condition is influenced by many factors, age-related changes in immune function including immune cell dynamics, and chronic inflam
Externí odkaz:
https://doaj.org/article/38b35da14abd4113aea8418d3056eefe
Autor:
Qianjin Wang, Can Cui, Ning Zhang, Wujian Lin, Senlin Chai, Simon Kwoon-Ho Chow, Ronald Man Yeung Wong, Yong Hu, Sheung Wai Law, Wing-Hoi Cheung
Publikováno v:
Journal of Orthopaedic Translation, Vol 46, Iss , Pp 91-102 (2024)
The neuromuscular junction (NMJ) is a specialized chemical synapse that converts neural impulses into muscle action. Age-associated NMJ degeneration, which involves nerve terminal and postsynaptic decline, denervation, and loss of motor units, signif
Externí odkaz:
https://doaj.org/article/ec38dc36d22a4101ac8f85d4613ac017
Autor:
Junichi Kushioka, Simon Kwoon-Ho Chow, Masakazu Toya, Masanori Tsubosaka, Huaishuang Shen, Qi Gao, Xueping Li, Ning Zhang, Stuart B. Goodman
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-13 (2023)
Abstract Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction is essential to initiate healing
Externí odkaz:
https://doaj.org/article/492df4d05c164f499f07ee14eaf74a2d
Autor:
Alexa K. Pius, Masakazu Toya, Qi Gao, Max L. Lee, Yasemin Sude Ergul, Simon Kwoon-Ho Chow, Stuart Barry Goodman
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 340 (2024)
Max L. Lee was not included as an author in the original publication [...]
Externí odkaz:
https://doaj.org/article/df704c9c0b1841168493459e81d00077
Autor:
Simon Kwoon-Ho Chow, Carissa Hing-Wai Wong, Can Cui, Michelle Meng-Chen Li, Ronald Man Yeung Wong, Wing-Hoi Cheung
Publikováno v:
Journal of Orthopaedic Translation, Vol 36, Iss , Pp 83-90 (2022)
Background: All fracture repairs start with the innate immune system with the inflammatory response known as the inflammatory stage guided and driven by the secretion of chemokine by the ruptured tissue, followed by the sequential recruitment of neut
Externí odkaz:
https://doaj.org/article/ff044c8b87164b8ab9354bd04acd1ca5
Autor:
Xueping Li, Huaishuang Shen, Mao Zhang, Victoria Teissier, Ejun Elijah Huang, Qi Gao, Masanori Tsubosaka, Masakazu Toya, Junichi Kushioka, Chima V. Maduka, Christopher H. Contag, Simon Kwoon-Ho Chow, Ning Zhang, Stuart B. Goodman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDysregulated inflammation is associated with many skeletal diseases and disorders, such as osteolysis, non-union of fractures, osteonecrosis, osteoarthritis and orthopaedic infections. We previously showed that continuous infusion of lipopo
Externí odkaz:
https://doaj.org/article/3866be4baf1b416a8fb5443f32339990
Autor:
Masakazu Toya, Ning Zhang, Masanori Tsubosaka, Junichi Kushioka, Qi Gao, Xueping Li, Simon Kwoon-Ho Chow, Stuart B. Goodman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Novel minimally invasive strategies are needed to obtain robust bone healing in complex fractures and bone defects in the elderly population. Local cell therapy is one potential option for future treatment. Mesenchymal stromal cells (MSCs) are not on
Externí odkaz:
https://doaj.org/article/d3bdbe354d65433cbe662f853eba4d44
Autor:
Alexa K. Pius, Masakazu Toya, Qi Gao, Max L. Lee, Yasemin Sude Ergul, Simon Kwoon-Ho Chow, Stuart Barry Goodman
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 52 (2023)
Joint replacement is a common surgery and is predominantly utilized for treatment of osteoarthritis in the aging population. The longevity of many of these implants depends on bony ingrowth. Here, we provide an overview of current techniques in osteo
Externí odkaz:
https://doaj.org/article/34b0068af1b045269d7f81e1f370ad7a
Autor:
Yu-Feng Long, Simon Kwoon-Ho Chow, Can Cui, Ronald Man Yeung Wong, Ling Qin, Sheung-Wai Law, Wing-Hoi Cheung
Publikováno v:
Journal of Orthopaedic Translation, Vol 35, Iss , Pp 37-52 (2022)
Background: Sarcopenia is a hallmark of the ageing process, which is characterized by the decline in muscle mass and strength. Growing evidence indicates that mitochondria dysfunction play core roles in this process. Meanwhile, physical exercise is r
Externí odkaz:
https://doaj.org/article/395c06b90cf44278bbe00674ec76512f
Autor:
Chaoran Liu, Keith Yu-Kin Cheng, Xin Tong, Wing-Hoi Cheung, Simon Kwoon-Ho Chow, Sheung Wai Law, Ronald Man Yeung Wong
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundElderly people with low lean and high fat mass, are diagnosed with sarcopenic obesity (SO), and often have poor clinical outcomes. This study aimed to explore the relationship between obesity and sarcopenia, and the optimal proportion of fa
Externí odkaz:
https://doaj.org/article/75fd4df338374e9d991ebcb69825e4ae