Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Simon Kreiser"'
Autor:
Simon Kreiser, Joachim L. Schultze, Kevin Baßler, Matthias Lechmann, Alexander Steinkasserer, Petra Hoffmann, Matthias Edinger, Ilka Knippertz, Christine Seitz, Thomas Ulas, Lars Nitschke, Christina Koenig, Lena Stich, Marina Doebbeler, Alina Butterhof, Andreas B. Wild, Christin Riegel, Dmitry Kopelyanskiy, Elisabeth Zinser, Lena Krzyzak, Christine Kuhnt, Thomas Winkler, Stefan Wirtz
Publikováno v:
JCI Insight. 3
Foxp3-positive regulatory T cells (Tregs) are crucial for the maintenance of immune homeostasis and keep immune responses in check. Upon activation, Tregs are transferred into an effector state expressing transcripts essential for their suppressive a
Autor:
Christine Tucher, Alexander Steinkasserer, Christine Seitz, Claudia Günther, Ilka Knippertz, Matthias Lechmann, Simon Kreiser, Marcello F. Stein, Jenny Eckhardt, Christoph Becker, Christine Kuhnt, Lena Krzyzak
Publikováno v:
Immunobiology. 220:270-279
The CD83 molecule (CD83) is a well-known surface marker present on mature dendritic cells (mDC). In this study, we show that CD83 is also expressed on a subset of T cells which mediate regulatory T cell (Treg)-like suppressor functions in vitro and i
Autor:
Christian Ostalecki, Claudia Günther, Irina Y. Tcherepanova, Elisabeth Zinser, M. Döbbeler, Charles A. Nicolette, Christoph Becker, Tak W. Mak, Jenny Eckhardt, Ansgar J. Pommer, Alexander Steinkasserer, Mark A. DeBenedette, Simon Kreiser, Matthias Lechmann
Publikováno v:
Mucosal Immunology. 7:1006-1018
The physiological balance between pro- and anti-inflammatory processes is dysregulated in inflammatory bowel diseases (IBD) as in Crohn's disease and ulcerative colitis. Conventional therapy uses anti-inflammatory and immunosuppressive corticosteroid