Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simon K. Krebs"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Incorporation of noncanonical amino acids (ncAAs) with bioorthogonal reactive groups by amber suppression allows the generation of synthetic proteins with desired novel properties. Such modified molecules are in high demand for basic research and the
Externí odkaz:
https://doaj.org/article/52c134ab610545c3aabf8003329953e5
Autor:
Simon K. Krebs, Marlitt Stech, Felix Jorde, Nathanaël Rakotoarinoro, Franziska Ramm, Sophie Marinoff, Sven Bahrke, Antje Danielczyk, Doreen A. Wüstenhagen, Stefan Kubick
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13697 (2022)
Recombinant immunotoxins (RITs) are an effective class of agents for targeted therapy in cancer treatment. In this article, we demonstrate the straight-forward production and testing of an anti-CD7 RIT based on PE24 in a prokaryotic and a eukaryotic
Externí odkaz:
https://doaj.org/article/5690bafebb7840d7809634ffa615c64c
Autor:
Ilja Demuth, Simon K Krebs, Véronique Dutrannoy, Christian Linke, Sylvia Krobitsch, Raymonda Varon, Christine Lang, Andreas Raab, Karl Sperling, Martin Digweed
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207315 (2018)
The genes, XRS2 in Saccharomyces cerevisiae and NBN in mammals, have little sequence identity at the amino acid level. Nevertheless, they are both found together with MRE11 and RAD50 in a highly conserved protein complex which functions in the repair
Externí odkaz:
https://doaj.org/article/d4b8c756a8a747738a251600a0b98f70
Publikováno v:
Journal of Neurochemistry. 111:192-203
Lewy bodies, alpha-synuclein (alpha-syn) immunopositive intracellular deposits, are the pathological hallmark of Parkinson's disease (PD). Interestingly, Lewybody-like structures have been identified in fetal tissue grafts about one decade after tran