Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Simon J. Lee"'
Publikováno v:
IEEE Access, Vol 8, Pp 179281-179294 (2020)
Typical radar detectors exploit only a small proportion of the valuable information contained in radar reflections, i.e. magnitude and Doppler. A neural network-based approach for augmenting traditional radar detector structures using machine learnin
Externí odkaz:
https://doaj.org/article/cf68dbb247734de0a257eb425564cbcd
Autor:
Tomas Malinauskas, Gareth Moore, Amalie F. Rudolf, Holly Eggington, Hayley L. Belnoue-Davis, Kamel El Omari, Samuel C. Griffiths, Rachel E. Woolley, Ramona Duman, Armin Wagner, Simon J. Leedham, Clair Baldock, Hilary L. Ashe, Christian Siebold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Twisted gastrulation (TWSG1) is an evolutionarily conserved secreted glycoprotein which controls signaling by Bone Morphogenetic Proteins (BMPs). TWSG1 binds BMPs and their antagonist Chordin to control BMP signaling during embryonic develop
Externí odkaz:
https://doaj.org/article/ddfaa798787944ee8ae8169dabd72ec6
Publikováno v:
IEEE Access, Vol 8, Pp 179281-179294 (2020)
Typical radar detectors exploit only a small proportion of the valuable information contained in radar reflections, i.e. magnitude and Doppler. A neural network-based approach for augmenting traditional radar detector structures using machine learnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46df97f27e59bf88a4462405fa7ca1d3
https://doi.org/10.1109/access.2020.3025144
https://doi.org/10.1109/access.2020.3025144
Publikováno v:
Biological Imaging, Vol 4 (2024)
Imaging platforms for generating highly multiplexed histological images are being continually developed and improved. Significant improvements have also been made in the accuracy of methods for automated cell segmentation and classification. However,
Externí odkaz:
https://doaj.org/article/f9de153b25ec4024a816ba01e8a5871e
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gundaz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It remains critical to identify colorectal cancers (CRC) that will disseminate as early as possible. Here, the authors identify CRC tumours that are aggressive and prone to early dissemination, characterised by epithelial TGFβ and growth-factor sign
Externí odkaz:
https://doaj.org/article/685f337608c24440b7e084866104173a
Autor:
Wuroud Al-khayyat, Jake Pirkkanen, Jessica Dougherty, Taylor Laframboise, Noah Dickinson, Neelam Khaper, Simon J. Lees, Marc S. Mendonca, Douglas R. Boreham, Tze Chun Tai, Christopher Thome, Sujeenthar Tharmalingam
Publikováno v:
Cells, Vol 12, Iss 19, p 2344 (2023)
FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily. FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in response to extracellular signals, leading to downstream cellular p
Externí odkaz:
https://doaj.org/article/97e78abc7b564ab78a3bf94c76304faa
Publikováno v:
American journal of medical genetics. Part A. (8)
A mother and daughter with an overlapping Catel–Manzke and Temtamy preaxial brachydactyly hyperphalangism syndrome phenotype are reported. We describe a phenotype with a previously undescribed genetic basis. © 2013 Wiley Periodicals, Inc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd99b0220b235eee2341657c58cbaf12
https://pubmed.ncbi.nlm.nih.gov/24677810
https://pubmed.ncbi.nlm.nih.gov/24677810
Autor:
Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Right-sided colorectal cancer (rCRC) has a different mutational spectrum to the left-sided counterpart. Here the authors develop a mouse model of rCRC that recapitulates human BRAF-mutant rCRC and show that loss of TGFβ-receptor signalling and infla
Externí odkaz:
https://doaj.org/article/e406c430dd004d04b04b4ed7f56f1c67
Publikováno v:
Physiological Reports, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Adipose tissue (AT) has been found to exist in two predominant forms, white and brown. White adipose tissue (WAT) is the body's conventional storage organ, and brown adipose tissue (BAT) is responsible for non‐shivering thermogenesis which
Externí odkaz:
https://doaj.org/article/e139dedec2f4433694638299ac2c502b
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 67:1608
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e52c58a611ba283d9a90e25cf98f82
https://doi.org/10.1016/j.bjps.2014.09.018
https://doi.org/10.1016/j.bjps.2014.09.018