Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Simon J. Foote"'
Autor:
Tanya Sharma, Pooja S. Sridhar, Christopher Blackman, Simon J. Foote, John S. Allingham, Rajagopal Subramaniam, Michele C. Loewen
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Fungal hyphal chemotropism has been shown to be a major contributor to host-pathogen interactions. Previous studies on Fusarium species have highlighted the involvement of the Ste2 G-protein-coupled receptor (GPCR) in mediating polarized hyp
Externí odkaz:
https://doaj.org/article/6a5c631b1a2c492ebbe274523f380b21
Autor:
Matthew A. Field, Gaetan Burgio, Aaron Chuah, Jalila Al Shekaili, Batool Hassan, Nashat Al Sukaiti, Simon J. Foote, Matthew C. Cook, T. Daniel Andrews
Publikováno v:
BMC Genomics, Vol 20, Iss S8, Pp 1-9 (2019)
Abstract Background Short-read resequencing of genomes produces abundant information of the genetic variation of individuals. Due to their numerous nature, these variants are rarely exhaustively validated. Furthermore, low levels of undetected varian
Externí odkaz:
https://doaj.org/article/7149218fe3724c40ba59eaeaf72d6345
Autor:
Cilly Bernardette Schnider, Hao Yang, Lora Starrs, Anna Ehmann, Farid Rahimi, Elena Di Pierro, Giovanna Graziadei, Kathryn Matthews, Tania De Koning-Ward, Denis C. Bauer, Simon J. Foote, Gaetan Burgio, Brendan J. McMorran
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
An important component in host resistance to malaria infection are inherited mutations that give rise to abnormalities and deficiencies in erythrocyte proteins and enzymes. Understanding how such mutations confer protection against the disease may be
Externí odkaz:
https://doaj.org/article/31219ec1b0fd46b18dc218d00ec47b2c
Autor:
Dian Ningtyas, Russell J. Thomson, Volga Tarlac, Shivashankar H. Nagaraj, Wendy Hoy, John D. Mathews, Simon J. Foote, Elizabeth E. Gardiner, Justin R. Hamilton, Brendan J. McMorran
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The F2RL3 gene encoding protease activated receptor 4 (PAR4) contains a single nucleotide variant, rs773902, that is functional. The resulting PAR4 variants, Thr120, and Ala120, are known to differently affect platelet reactivity to thrombin. Signifi
Externí odkaz:
https://doaj.org/article/7750e3e3a71b4504a0c4bf25224be957
Autor:
Patrick M. Lelliott, Hong Ming Huang, Matthew W. Dixon, Arman Namvar, Adam J. Blanch, Vijay Rajagopal, Leann Tilley, Cevayir Coban, Brendan J. McMorran, Simon J. Foote, Gaetan Burgio
Publikováno v:
Blood Advances, Vol 1, Iss 26, Pp 2624-2636 (2017)
Abstract: The malaria parasite hijacks host erythrocytes to shield itself from the immune system and proliferate. Red blood cell abnormalities can provide protection from malaria by impeding parasite invasion and growth within the cell or by compromi
Externí odkaz:
https://doaj.org/article/b904422884f74753812651a6cc48230a
Autor:
Hong Ming Huang, Denis C. Bauer, Patrick M. Lelliott, Matthew W. A. Dixon, Leann Tilley, Brendan J. McMorran, Simon J. Foote, Gaetan Burgio
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 9, Pp 3133-3144 (2017)
Allelic heterogeneity is a common phenomenon where a gene exhibits a different phenotype depending on the nature of its genetic mutations. In the context of genes affecting malaria susceptibility, it allowed us to explore and understand the intricate
Externí odkaz:
https://doaj.org/article/9bad8ce2bed54c3aaf6b8f0f966deb1b
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Clonostachys rosea strain ACM941 is a fungal bio-control agent patented against the causative agent of Fusarium Head Blight, Fusarium graminearum. Although the molecular details remain enigmatic, previous studies have suggested that C. rosea may secr
Externí odkaz:
https://doaj.org/article/72fb80be08114900845f3dfa1380204a
Autor:
Ashlee J. Conway, Fiona C. Brown, Elinor J. Hortle, Gaetan Burgio, Simon J. Foote, Craig J. Morton, Stephen M. Jane, David J. Curtis
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 5 (2018)
In this study, we performed a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen in mice to identify novel genes or alleles that regulate erythropoiesis. Here, we describe a recessive mouse strain, called RBC19, harbouring a point mutation wi
Externí odkaz:
https://doaj.org/article/101b20633020402284610baa4ad6512a
Autor:
Brendan J. McMorran, Arvind Jaya Shankar, Simon J. Foote, Vinod Scaria, Sudhir Jadhao, Wendy E. Hoy, Hardip R. Patel, Shivashankar H. Nagaraj
Publikováno v:
The Pharmacogenomics Journal. 22:100-108
Indigenous Australians face a disproportionately severe burden of chronic disease relative to other Australians, with elevated rates of morbidity and mortality. While genomics technologies are slowly gaining momentum in personalised treatments for ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::629eb2852f7eef4e5ca7b236b1d18539
https://doi.org/10.1038/s41397-021-00262-4
https://doi.org/10.1038/s41397-021-00262-4
Autor:
Simon J. Foote, Anne Johnston, David P. Overy, Zerihun A Demissie, Thomas E. Witte, Amanda Sproule, Michele C. Loewen, Kelly A Robinson, Linda J. Harris
Publikováno v:
Molecular Plant-Microbe Interactions®. 33:842-858
The mycoparasite Clonostachys rosea ACM941 is under development as a biocontrol organism against Fusarium graminearum, the causative agent of Fusarium head blight in cereals. To identify molecular factors associated with this interaction, the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6734a8163efc236ba78c1cded5493614
https://doi.org/10.1094/mpmi-11-19-0310-r
https://doi.org/10.1094/mpmi-11-19-0310-r