Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Simon J. F. Harper"'
Autor:
G.R. Bicknell, Sarah A. Hosgood, Monika Kaushik, Michael L. Nicholson, Bin Yang, Atul Bagul, Helen L. Waller, Simon J. F. Harper, Mark D. Kay
Publikováno v:
Transplant International. 20:625-631
The optimal kidney preservation system and methods to ameliorate reperfusion injury are major factors in accomplishing successful graft function following transplantation. Ischaemia and reperfusion lead to cellular stress and the adaptive response ma
Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant
Autor:
Ines G, Harper, Jason M, Ali, Simon J F, Harper, Elizabeth, Wlodek, Jawaher, Alsughayyir, Margaret C, Negus, M Saeed, Qureshi, Reza, Motalleb-Zadeh, Kourosh, Saeb-Parsy, Eleanor M, Bolton, J Andrew, Bradley, Menna R, Clatworthy, Thomas M, Conlon, Gavin J, Pettigrew
Publikováno v:
Cell Reports
Summary Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown. Using m
Autor:
Reyad A, Abbadi, Umar, Sadat, Asif, Jah, Raaj K, Praseedom, Neville V, Jamieson, Heok K, Cheow, Siobhan, Whitley, Hugo E, Ford, Charles B, Wilson, Simon J F, Harper, Emmanuel L, Huguet
Publikováno v:
Journal of surgical oncology. 110(3)
Actual long-term survival of patients with colorectal liver metastases staged by PET CT has not been reported. Objectives were to investigate whether PET CT staging results in actual improved long-term survival, to examine outcome in patients with 'e
Publikováno v:
British Journal of Pharmacology. 124:703-710
1. Previous studies have shown that ATP and UTP are able to stimulate phospholipase C (PLC) and proliferation in cultured aortic smooth muscle cells. Here we set out to characterize the receptor responsible, and investigate a possible role for p42 an
Autor:
Simon J F Harper, Sarah Cheslyn-Curtis
Publikováno v:
Annals of clinical biochemistry. 48(Pt 1)
Acute pancreatitis (AP) is an important cause of morbidity and mortality worldwide and the annual incidence appears to be increasing. It presents as a mild self-limiting illness in 80% of patients. However, one-fifth of these develop a severe complic
Autor:
Michael L. Nicholson, Mark D. Kay, Simon J. F. Harper, Helen L. Waller, Sarah A. Hosgood, Douglas Rees, Atul Bagul
Publikováno v:
Transplant international : official journal of the European Society for Organ Transplantation. 20(1)
The aim of this study was to assess the viability and function of renal allografts under normothermic conditions using a novel nonphosphate buffered preservation solution AQIXRS-I. Porcine kidneys were flushed at 30 degrees C with AQIXRS-I at 100 mmH
Autor:
Atul Bagul, Simon J. F. Harper, Michael L. Nicholson, Mark D. Kay, Helen L. Waller, Monika Kaushik, Bin Yang, Sarah A. Hosgood
Publikováno v:
Free radical research. 40(11)
Ischaemia-reperfusion (IR) injury is known to be a risk factor influencing both short and long-term graft function following transplantation. The pathophysiology of IR injury is suggested to involve elevated reactive oxygen species production resulti
Autor:
Nicholas R. Brook, Monika Kaushik, Atul Bagul, Mark D. Kay, Michael L. Nicholson, Simon J. F. Harper
Publikováno v:
BJU international. 98(4)
OBJECTIVE To compare the anatomy and function of right and left kidneys retrieved by laparoscopic live donor nephrectomy (LDN). PATIENTS AND METHODS In all, 84 transperitoneal LDNs were performed, 66 left and 18 right. Two different right-sided LDN t
Publikováno v:
Transplantation Proceedings. 37:625-626
The technical challenges of laparosopcic transperitoneal donor nephrectomy (LapDN) have raised concerns over the quality of the procured allografts. This study reports the anatomical and functional outcomes of kidneys retrieved from 60 live donors en