Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Simon J Furney"'
Autor:
Nicola Cosgrove, Alex J. Eustace, Peter O’Donovan, Stephen F. Madden, Bruce Moran, John Crown, Brian Moulton, Patrick G. Morris, Liam Grogan, Oscar Breathnach, Colm Power, Michael Allen, Janice M. Walshe, Arnold D. Hill, Anna Blümel, Darren O’Connor, Sudipto Das, Małgorzata Milewska, Joanna Fay, Elaine Kay, Sinead Toomey, Bryan T. Hennessy, Simon J. Furney
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract HER2-positive (HER2+) breast cancer accounts for 20–25% of all breast cancers. Predictive biomarkers of neoadjuvant therapy response are needed to better identify patients with early stage disease who may benefit from tailored treatments i
Externí odkaz:
https://doaj.org/article/2aa94f4a6ce8446ea48464a6049912d0
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-16 (2023)
Abstract Background Genome-wide association studies (GWAS) have highlighted over 200 autosomal variants associated with multiple sclerosis (MS). However, variants in non-coding regions such as those encoding microRNAs have not been explored thoroughl
Externí odkaz:
https://doaj.org/article/4812792daf64487cbc529f87755aef41
Autor:
Isabelle Boothman, Lisa M. Clayton, Mark McCormack, Alexandra McKibben Driscoll, Remi Stevelink, Patrick Moloney, Roland Krause, Wolfram S. Kunz, Sarah Diehl, Terence J. O’Brien, Graeme J. Sills, Gerrit-Jan de Haan, Federico Zara, Bobby P. Koeleman, Chantal Depondt, Anthony G. Marson, Hreinn Stefansson, Kari Stefansson, John Craig, Michael R. Johnson, Pasquale Striano, Holger Lerche, Simon J. Furney, Norman Delanty, Consortium EpiPGX, Sanjay M. Sisodiya, Gianpiero L. Cavalleri, Joseph Willis, Mojgansadat Borghei, Simona Donatello, Martin J. Brodie, Pauls Auce, Andrea Jorgensen, Sarah R. Langley, Yvonne Weber, Christian Hengsbach, Martin Krenn, Fritz Zimprich, Ekaterina Pataraia, Karl Martin Klein, Hiltrud Muhle, Rikke S. Møller, Marina Nikanorova, Stefan Wolking, Ellen Campbell, Antonella Riva, Marcello Scala
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundThe anti-seizure medication vigabatrin (VGB) is effective for controlling seizures, especially infantile spasms. However, use is limited by VGB-associated visual field loss (VAVFL). The mechanisms by which VGB causes VAVFL remains unknown.
Externí odkaz:
https://doaj.org/article/9ba7aecc0196466792d32bdb7c7d0945
Autor:
Ian S. Reynolds, Valentina Thomas, Emer O’Connell, Michael Fichtner, Deborah A. McNamara, Elaine W. Kay, Jochen H. M. Prehn, John P. Burke, Simon J. Furney
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/518cc9f3e442435ebcdf4de825574ae9
Autor:
Timothy Budden, Caroline Gaudy-Marqueste, Andrew Porter, Emily Kay, Shilpa Gurung, Charles H. Earnshaw, Katharina Roeck, Sarah Craig, Víctor Traves, Jean Krutmann, Patricia Muller, Luisa Motta, Sara Zanivan, Angeliki Malliri, Simon J. Furney, Eduardo Nagore, Amaya Virós
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Ultraviolet radiation (UVR) increases melanoma incidence. Here, the authors report that UVR-damaged dermal fibroblasts upregulate MMP1 to degrade collagen which inhibits melanoma invasion and that aged primary melanomas in skin with degraded collagen
Externí odkaz:
https://doaj.org/article/f3eebf3f892a42e28f17cc0ebdce6bf8
Autor:
Ian S. Reynolds, Valentina Thomas, Emer O’Connell, Michael Fichtner, Deborah A. McNamara, Elaine W. Kay, Jochen H. M. Prehn, John P. Burke, Simon J. Furney
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
IntroductionMucinous adenocarcinoma of the rectum is an infrequently encountered histological subtype that is associated with an impaired response to chemoradiotherapy and a worse overall prognosis. A genomic profile analysis of mucinous rectal tumor
Externí odkaz:
https://doaj.org/article/513b3d6311d241e6806a353b4fb6d6ee
Autor:
Richard Marais, Caroline Dive, Paul Lorigan, Ged Brady, Nathalie Dhomen, Deemesh Oudit, Alberto Fusi, Matthew Smith, Jacqueline Swan, Jane Rogan, Malin Pedersen, Franziska Baenke, Simon J. Furney, Grazia Saturno, Kok Haw Jonathan Lim, Amit Kumar Mandal, Amaya Viros, Dominic Rothwell, Elena Galvani, Rebecca Lee, Gabriela Gremel, Maria Romina Girotti
40 Gene Miseq primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5814132d325f0455f16950de381c5fe4
https://doi.org/10.1158/2159-8290.22531439.v1
https://doi.org/10.1158/2159-8290.22531439.v1
Autor:
Richard Marais, Marc-Henri Stern, Sergio Roman-Roman, Pierre de la Grange, Sophie Piperno-Neumann, Samra Turajlic, Laurence Desjardins, Audrey Rapinat, Amaury G. Dumont, David Gentien, Malin Pedersen, Simon J. Furney
Supplementary Methods - PDF file 148K, Contains supplementary methods used in data analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff688336d6aacdad029d2ec5f76c033
https://doi.org/10.1158/2159-8290.22528830.v1
https://doi.org/10.1158/2159-8290.22528830.v1
Autor:
Richard Marais, Marc-Henri Stern, Sergio Roman-Roman, Pierre de la Grange, Sophie Piperno-Neumann, Samra Turajlic, Laurence Desjardins, Audrey Rapinat, Amaury G. Dumont, David Gentien, Malin Pedersen, Simon J. Furney
Supplementary Tables 1-12 - XLSX file 156K, This file contains Supplementary Tables 1-12. Supplementary Table 1. Clinical information of 12 patients in discovery cohort. Supplementary Table 2. Whole genome sequnecing coverage of uveal melanoma sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0cf4c8a680ea5472c3e56a2c7048fc
https://doi.org/10.1158/2159-8290.22528827.v1
https://doi.org/10.1158/2159-8290.22528827.v1
Autor:
Richard Marais, Marc-Henri Stern, Sergio Roman-Roman, Pierre de la Grange, Sophie Piperno-Neumann, Samra Turajlic, Laurence Desjardins, Audrey Rapinat, Amaury G. Dumont, David Gentien, Malin Pedersen, Simon J. Furney
Supplementary Figures S1-S7 - PDF file 4131K, This file contains Supplementary Figures S1-S7. S1 Summary of somatic copy number alterations in uveal melanoma S2 Circos plots of uveal melanoma genomes S3 Distribution of missense mutations in SF3B1 S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098a3d82fcad85ef883842f12c5255db
https://doi.org/10.1158/2159-8290.22528833.v1
https://doi.org/10.1158/2159-8290.22528833.v1