Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Simon J, Moore"'
Autor:
Emily J. Johnston, Jess Tallis, Edward Cunningham-Oakes, Tessa Moses, Simon J. Moore, Sarah Hosking, Susan J. Rosser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Escin is a mixture of over 30 glycosylated triterpenoid (saponin) structures, extracted from the dried fruit of horse chestnuts. Escin is currently used as an anti-inflammatory, and has potential applications in the treatment of arthritis an
Externí odkaz:
https://doaj.org/article/45fe8550be604c0293f915b1a5d6929d
Publikováno v:
Engineering Biology, Vol 6, Iss 2-3, Pp 62-68 (2022)
Abstract In synthetic biology, biosensors are routinely coupled with a gene expression system for detecting small molecules and physical signals. We reveal a fluorescent complex, based on the interaction of an Escherichia coli double bond reductase (
Externí odkaz:
https://doaj.org/article/ca0717437d9b49178306015f883d97e3
Autor:
Lakshmeesha K. Nagappa, Wakana Sato, Farzana Alam, Kameshwari Chengan, Christopher M. Smales, Tobias Von Der Haar, Karen M. Polizzi, Katarzyna P. Adamala, Simon J. Moore
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cell-free gene expression (CFE) systems are an attractive tool for engineering within synthetic biology and for industrial production of high-value recombinant proteins. CFE reactions require a cell extract, energy system, amino acids, and DNA, to ca
Externí odkaz:
https://doaj.org/article/918bd92301994b41802d8d3e7a95371a
Autor:
Simon J. Moore, Yonek B. Hleba, Sarah Bischoff, David Bell, Karen M. Polizzi, Paul S. Freemont
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background A key focus of synthetic biology is to develop microbial or cell-free based biobased routes to value-added chemicals such as fragrances. Originally, we developed the EcoFlex system, a Golden Gate toolkit, to study genes/pathways f
Externí odkaz:
https://doaj.org/article/a7517874ba71408894243205086980df
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/1d4f3aa2d73643108f716b71bcee4bf2
Autor:
Simon J. Moore, Yonek B. Hleba, Sarah Bischoff, David Bell, Karen M. Polizzi, Paul S. Freemont
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/218aa91a2e9441c4a45554578d2b6ece
Publikováno v:
Natural Product Reports. 40:228-236
Streptomyces cell-free gene expression (CFE) systems for natural product discovery. The CFE system simply requires DNA, a cell-extract, amino acids, and a metabolite solution to study transcription, translation, and biosynthesis in a single reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d8c124d89a0d7002372e2ef1ccdef4b
https://doi.org/10.1039/d2np00057a
https://doi.org/10.1039/d2np00057a
Autor:
Kameshwari Chengan, Charlotte Hind, Lakshmeesha Nagappa, Matthew E. Wand, Tanith Hanson, Ruben Martin Escolano, Anastasios Tsaousis, José A Bengoechea, J. Mark Sutton, Christopher M Smales, Simon J Moore
Antimicrobial resistance (AMR) is a pandemic spread across multiple priority infectious disease threats. While the cell envelope plays a key role in AMR, this also makes it challenging to study how antibiotics function inside the cell. Herein, we pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28abbcf93fd4efac33b02a15378d335a
https://doi.org/10.1101/2023.04.13.536698
https://doi.org/10.1101/2023.04.13.536698
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Over 30 years, the Gram-positive bacterium Priestia megaterium (previously known as Bacillus megaterium) was systematically developed for biotechnological applications ranging from the production of small molecules like vitamin B12, over pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f58000d7fd3018c9420f589e03014ba
https://doi.org/10.1007/s00253-021-11424-6
https://doi.org/10.1007/s00253-021-11424-6
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac35a13b1928baaaeb2f6987b33af61
https://www.frontiersin.org/articles/10.3389/fbioe.2021.799122/full
https://www.frontiersin.org/articles/10.3389/fbioe.2021.799122/full