Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Simon I. R. Lane"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
During ‘meiotic drive’, some chromosomes can bias their spindle orientation and thus be retained in the egg. Here, the authors find that this phenomenon can be driven by microtubule force asymmetry on chromosomes with differently sized centromere
Externí odkaz:
https://doaj.org/article/0953c7263e2847f793b9899690e89c1c
Autor:
Simon I. R. Lane, Maaike S. A. Jongen, Owen J. T. McCarty, Jonathan West, Nicola A. Englyst, Paul M. Holloway
Publikováno v:
Cell Mol Bioeng
Introduction: Precision mapping of the functional structure of platelet populations holds great promise for the identification of hyper-reactive subtypes that are likely to be disease drivers, having value in prognostics and as therapeutic targets. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cada9b484f709cd898b73c23fe8942c4
https://eprints.soton.ac.uk/446770/
https://eprints.soton.ac.uk/446770/
Autor:
Simon I. R. Lane, Liisa Kauppi
Publikováno v:
Cellular and Molecular Life Sciences
The production of gametes (sperm and eggs in mammals) involves two sequential cell divisions, meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate to different daughter cells, and meiosis II resembles mitotic divisions in that sis
Autor:
Timothy J. Underwood, Jonathan Butement, Marta E Polak, Maaike S. A. Jongen, Andres F. Vallejo, Bhavwanti Sheth, Simon I. R. Lane, Rachel Parker, Ben D. MacArthur, Rosanna C.G. Smith, Matthew J. J. Rose-Zerilli, Jack Harrington, Patrick S. Stumpf, Luis Blay Esteban, Jonathan West
The future of single cell diversity screens involves ever-larger sample sizes, dictating the need for higher throughput methods with low analytical noise to accurately describe the nature of the cellular system. Current approaches are limited by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b978739ab39f9032cfb38584f3333c2
https://doi.org/10.1101/2021.04.08.439026
https://doi.org/10.1101/2021.04.08.439026
Publikováno v:
The Journal of cell biology. 220(10)
The repetitive sequences of DNA centromeric regions form the structural basis for kinetochore assembly. Recently they were found to be transcriptionally active in mitosis, with their RNAs providing noncoding functions. Here we explore the role, in mo
Second Harmonic Generation Light Sheet Microscopy (SHG-LSM): A new tool for label-free 3D bioimaging
Autor:
Mark Jones, Robert A. Ridley, Christopher J. Brereton, Robert Forster, Sumeet Mahajan, Donna E. Davies, Gunnar Spickermann, Simon I. R. Lane, Konstantinos N. Bourdakos, Niall Hanrahan, Graeme P. A. Malcolm, Elizabeth R. Davies, Neveen A. Hosny, Peter Johnson
Publikováno v:
Biophotonics and Biomedical Microscopy.
Autor:
Mark Jones, Robert A. Ridley, Konstantinos N. Bourdakos, Niall Hanrahan, Christopher J. Brereton, Peter B. Johnson, Elizabeth R. Davies, Robert Forster, Donna E. Davies, Neveen A. Hosny, Graeme Malcolm, Sumeet Mahajan, Gunnar Spickermann, Simon I. R. Lane
Publikováno v:
bioRxiv
Light sheet microscopy (LSM) has emerged as one of most profound three dimensional (3D) imaging tools in the life sciences over the last decade. However, LSM is currently performed with fluorescence detection on one- or multi-photon excitation. Label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea600526becd4ba331b4aace82531d5a
https://doi.org/10.1101/2020.09.07.284703
https://doi.org/10.1101/2020.09.07.284703
Autor:
Keith T. Jones, Simon I. R. Lane
Publikováno v:
The Journal of Cell Biology
Lane and Jones use serial bisection of mouse oocytes to analyze the influence of cytoplasmic volume on spindle assembly checkpoint function. Volume reduction promotes inhibition of APC but cannot prevent chromosome segregation errors at anaphase.
Autor:
Jonathan West, Jonathan Butement, Jack Harrington, John S. Shrimpton, Timothy J. Underwood, Simon I. R. Lane
Publikováno v:
Lab on a chip. 19(22)
Particle sedimentation is deleterious to a tremendous variety of microfluidic applications. Using an open instrumentation approach we show that syringe rotation retains particles in a suspended state, providing a universal solution for the continuous
Autor:
Marie-Hélène Verlhac, Joanne Kanaan, Marion Manil-Ségalen, Małgorzata Łuksza, Simon I. R. Lane, Marie-Emilie Terret, Keith T. Jones, Renata Basto, Véronique Marthiens
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (10), pp.3416-3430. ⟨10.1083/jcb.201806072⟩
Journal of Cell Biology, Rockefeller University Press, 2018, 217, pp.3416-3430. ⟨10.1083/jcb.201806072⟩
Journal of Cell Biology, 2018, 217, pp.3416-3430. ⟨10.1083/jcb.201806072⟩
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (10), pp.3416-3430. ⟨10.1083/jcb.201806072⟩
Journal of Cell Biology, Rockefeller University Press, 2018, 217, pp.3416-3430. ⟨10.1083/jcb.201806072⟩
Journal of Cell Biology, 2018, 217, pp.3416-3430. ⟨10.1083/jcb.201806072⟩
The Journal of Cell Biology
Acentrosomal spindle assembly in mouse oocytes depends on chromosomes and acentriolar microtubule-organizing centers (aMTOCs). Manil-Ségalen et al. observe that Plk4-induced perturbation of aMTOCs coupled to Cre-mediated gene editing generates fragi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fed290d4c2afcaa1c558a019ad21eae
https://hal.archives-ouvertes.fr/hal-03453036
https://hal.archives-ouvertes.fr/hal-03453036