Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Simon I. Dreher"'
Autor:
Solvig Diederichs, Simon I. Dreher, Sarah Anna Nüesch, Sven Schmidt, Christian Merle, Wiltrud Richter
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background In vitro chondrogenesis of mesenchymal stromal cells (MSCs) driven by the essential chondro-inducer transforming growth factor (TGF)-β is instable and yields undesired hypertrophic cartilage predisposed to bone formation in vivo.
Externí odkaz:
https://doaj.org/article/c05f8ba30a654773992e8de861edb4b3
Autor:
Svitlana Melnik, Jessica Gabler, Simon I. Dreher, Nicole Hecht, Nina Hofmann, Tobias Großner, Wiltrud Richter
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Background Human mesenchymal stromal cells (MSC) hold hopes for cartilage regenerative therapy due to their chondrogenic differentiation potential. However, undesirable occurrence of calcification after ectopic transplantation, known as hype
Externí odkaz:
https://doaj.org/article/f0eecec0cb6e4cdeb16edcf683b0256e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better understand h
Externí odkaz:
https://doaj.org/article/79ac17833fb94a86b94d6c8288125e03
Autor:
Simon I. Dreher, Selina Höckele, Peter Huypens, Martin Irmler, Christoph Hoffmann, Tim Jeske, Maximilian Hastreiter, Anja Moller, Andreas L. Birkenfeld, Hans-Ulrich Häring, Andreas Peter, Johannes Beckers, Martin Hrabě de Angelis, Cora Weigert
Publikováno v:
Cells, Vol 10, Iss 12, p 3443 (2021)
Physical training improves insulin sensitivity and can prevent type 2 diabetes (T2D). However, approximately 20% of individuals lack a beneficial outcome in glycemic control. TGF-β, identified as a possible upstream regulator involved in this low re
Externí odkaz:
https://doaj.org/article/e7802b730a534fd0bc3a53e75827922f
Autor:
Simon I. Dreher, Paul Grubba, Alessia Moruzzi, Christine von Toerne, Thomas Goj, Andreas L. Birkenfeld, Andreas Peter, Stefanie Hauck, Peter Loskill, Cora Weigert
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Simon I. Dreher, Martin Irmler, Martin Hrabě de Angelis, Johannes Beckers, Andreas L. Birkenfeld, Andreas Peter, Andreas Niess, Anja Moller, Cora Weigert
Publikováno v:
Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.
Autor:
Andreas Geisbüsch, Veronika Tonnier, Solvig Diederichs, Simon I. Dreher, Wiltrud Richter, Melanie März
Publikováno v:
Cellular and Molecular Life Sciences. 76:3875-3889
Re-directing mesenchymal stromal cell (MSC) chondrogenesis towards a non-hypertrophic articular chondrocyte-(AC)-like phenotype is important for improving articular cartilage neogenesis to enhance clinical cartilage repair strategies. This study is t