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Akademický článek

Dynamically cultured, differentiated bovine adipose-derived stem cell spheroids as building blocks for biofabricating cultured fat

Autor: Annemarie Klatt, Jannis O. Wollschlaeger, Franziska B. Albrecht, Sara Rühle, Lena B. Holzwarth, Holger Hrenn, Tanja Melzer, Simon Heine, Petra J. Kluger

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract Cultured or cultivated meat, animal muscle, and fat tissue grown in vitro, could transform the global meat market, reducing animal suffering while using fewer resources than traditional meat production and no antimicrobials at all. To ensure

Externí odkaz: https://doaj.org/article/4d0f92a363aa406695dd8f4a51ae1568

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Akademický článek

Herbicide risk assessments of non-target terrestrial plant communities: A graphical user interface for the plant community model IBC-grass.

Autor: Jette Reeg, Simon Heine, Christine Mihan, Sean McGee, Thomas G Preuss, Florian Jeltsch

Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0230012 (2020)

Plants located adjacent to agricultural fields are important for maintaining biodiversity in semi-natural landscapes. To avoid undesired impacts on these plants due to herbicide application on the arable fields, regulatory risk assessments are conduc

Externí odkaz: https://doaj.org/article/127e23ce2e0144998ab140a7b530e2ac

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Akademický článek

Scaffolds for Cultured Meat on the Basis of Polysaccharide Hydrogels Enriched with Plant-Based Proteins

Autor: Jannis O. Wollschlaeger, Robin Maatz, Franziska B. Albrecht, Annemarie Klatt, Simon Heine, Andreas Blaeser, Petra J. Kluger

Publikováno v: Gels, Vol 8, Iss 2, p 94 (2022)

The world population is growing and alternative ways of satisfying the increasing demand for meat are being explored, such as using animal cells for the fabrication of cultured meat. Edible biomaterials are required as supporting structures. Hence, w

Externí odkaz: https://doaj.org/article/7a16377b9aa4444e8395835f3d3d7d8e

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Akademický článek

Simulation of herbicide impacts on a plant community: comparing model predictions of the plant community model IBC-grass to empirical data

Autor: Jette Reeg, Simon Heine, Christine Mihan, Sean McGee, Thomas G. Preuss, Florian Jeltsch

Publikováno v: Environmental Sciences Europe, Vol 30, Iss 1, Pp 1-16 (2018)

Abstract Background Semi-natural plant communities such as field boundaries play an important ecological role in agricultural landscapes, e.g., provision of refuge for plant and other species, food web support or habitat connectivity. To prevent unde

Externí odkaz: https://doaj.org/article/09f3bfe2068942ebbfd1fcd7f36f6f04

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Akademický článek

Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA

Autor: Simon Heine, Markus Kleih, Neus Giménez, Kathrin Böpple, German Ott, Dolors Colomer, Walter E. Aulitzky, Heiko van der Kuip, Elisabeth Silkenstedt

Publikováno v: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-15 (2018)

Abstract Background Mantle cell lymphoma (MCL) is an aggressive B-non-Hodgkin lymphoma with generally poor outcome. MCL is characterized by an aberrantly high cyclin D1-driven CDK4 activity. New molecular targeted therapies such as inhibitors of the

Externí odkaz: https://doaj.org/article/3cf96957d1a94c81904cebab6bed8b4c

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Data from Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest

Autor: Heiko van der Kuip, Walter E. Aulitzky, Georg Sauer, Jens O. Schmid, Thomas E. Mürdter, Simon Heine, Christoph Ulmer, Matthias Schwab, Lea Schaaf

Although hyperthermia offers clinical appeal to sensitize cells to chemotherapy, this approach has been limited in terms of long-term outcome as well as economic and technical burden. Thus, a more detailed knowledge about how hyperthermia exerts its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f05276d2417a1ede94674951706699e
https://doi.org/10.1158/0008-5472.c.6507675

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Supplementary Figures 1-8 from Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest

Autor: Heiko van der Kuip, Walter E. Aulitzky, Georg Sauer, Jens O. Schmid, Thomas E. Mürdter, Simon Heine, Christoph Ulmer, Matthias Schwab, Lea Schaaf

Supplemental Figures (Supplementary Fig. 1-8): Cell lines are HR proficient (Supplementary Fig. 1); Influence of hyperthermia on the quantity of intra-nuclear Pt-DNA adducts and intracellular doxorubicin concentration (Supplementary Fig. 2); Hyperthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177814cc4f68030025201085d1034c0a
https://doi.org/10.1158/0008-5472.22409061.v1

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