Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Simon H. Rüdisser"'
Autor:
Giacomo Padroni, Maria Bikaki, Mihajlo Novakovic, Antje C. Wolter, Simon H. Rüdisser, Alvar D. Gossert, Alexander Leitner, Frederic H.-T Allain
Publikováno v:
Nucleic Acids Research, 51 (9)
The pandemic caused by SARS-CoV-2 has called for concerted efforts to generate new insights into the biology of betacoronaviruses to inform drug screening and development. Here, we establish a workflow to determine the RNA recognition and druggabilit
Autor:
Hannah A. Minas, Romain M. M. François, Franziska Hemmerling, Amy E. Fraley, Cora L. Dieterich, Simon H. Rüdisser, Roy A. Meoded, Sabrina Collin, Kira J. Weissman, Arnaud Gruez, Jörn Piel
Publikováno v:
Angewandte Chemie.
Publikováno v:
Journal of Biomolecular NMR. 74:579-594
Fluorine NMR has recently gained high popularity in drug discovery as it allows efficient and sensitive screening of large numbers of ligands. However, the positive hits found in screening must subsequently be ranked according to their affinity in or
Publikováno v:
Journal of biomolecular NMR. 74(10-11)
Fluorine NMR has recently gained high popularity in drug discovery as it allows efficient and sensitive screening of large numbers of ligands. However, the positive hits found in screening must subsequently be ranked according to their affinity in or
Autor:
Anna Knörlein, Jonathan Hall, Hasane Ratni, Simon H Rüdisser, Sarah Boigner, Laurent Gillioz, Antoine Cléry, Ahmed Moursy, Sébastien Campagne, Frédéric H.-T. Allain
Publikováno v:
Nature chemical biology. 15(12)
Splicing modifiers promoting SMN2 exon 7 inclusion have the potential to treat spinal muscular atrophy, the leading genetic cause of infantile death. These small molecules are SMN2 exon 7 selective and act during the early stages of spliceosome assem