Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Simon H, Jiang"'
Publikováno v:
BMC Rheumatology, Vol 7, Iss 1, Pp 1-21 (2023)
Abstract Background To determine the safety and efficacy of biological agents used in the treatment of systemic lupus erythematosus (SLE) in adults. Methods Systematic review and meta-analysis following PRISMA guidelines. Data sources MEDLINE (throug
Externí odkaz:
https://doaj.org/article/990c3aa7900b4c43937f528985d1625a
Autor:
Yi Tong V. Aw, Phillip J. Whiley, Ayla May Lorenzo, Tom Lea‐Henry, Somasundhari Shanmuganandam, Maurice Stanley, Sonia N. Babu, Vicki Athanasopoulos, Jean Cappello, Julia I. Ellyard, Matthew Cook, Carola Vinuesa, Giles Walters, David A. Fulcher, Simon H. Jiang
Publikováno v:
Rheumatology & Autoimmunity, Vol 3, Iss 1, Pp 15-25 (2023)
Abstract Background Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan involvement. Kidney involvement, termed lupus nephritis, has major impact on life expectancy
Externí odkaz:
https://doaj.org/article/cd66a9875c2c49ef8bb932bfc96e6597
Publikováno v:
Rheumatology & Autoimmunity, Vol 1, Iss 1, Pp 40-51 (2021)
Abstract Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by extraordinary heterogeneity, due to the complex pathogenesis and diverse manifestations. Stratification of patients for therapy and prognosis represents a m
Externí odkaz:
https://doaj.org/article/06c9ebdb5d9f4d78bdc1ba717986986f
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101375- (2022)
Summary: Accumulation of immunoglobulin and complement components within the kidneys is a hallmark of glomerulonephritis. Staining and detection of IgG, IgA, IgM, and C3 deposits can assist in diagnosing the underlying causes of nephritis and has imp
Externí odkaz:
https://doaj.org/article/1ed12ee464494e1fb9430e833cec0427
Autor:
Simon H. Jiang, Vicki Athanasopoulos, Julia I. Ellyard, Aaron Chuah, Jean Cappello, Amelia Cook, Savit B. Prabhu, Jacob Cardenas, Jinghua Gu, Maurice Stanley, Jonathan A. Roco, Ilenia Papa, Mehmet Yabas, Giles D. Walters, Gaetan Burgio, Kathryn McKeon, James M. Byers, Charlotte Burrin, Anselm Enders, Lisa A. Miosge, Pablo F. Canete, Marija Jelusic, Velibor Tasic, Adrian C. Lungu, Stephen I. Alexander, Arthur R. Kitching, David A. Fulcher, Nan Shen, Todor Arsov, Paul A. Gatenby, Jeff J. Babon, Dominic F. Mallon, Carmen de Lucas Collantes, Eric A. Stone, Philip Wu, Matthew A. Field, Thomas D. Andrews, Eun Cho, Virginia Pascual, Matthew C. Cook, Carola G. Vinuesa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Function-altering variants of immune-related genes cause rare autoimmune syndromes, whereas their contribution to common autoimmune diseases remains uncharacterized. Here the authors show that rare variants of lupus-associated genes are present in th
Externí odkaz:
https://doaj.org/article/78a180011b6f49c096a0159adcd221f4
Autor:
Yi Tong V. Aw, Phillip J. Whiley, Ayla May Lorenzo, Tom Lea‐Henry, Somasundhari Shanmuganandam, Maurice Stanley, Sonia N. Babu, Vicki Athanasopoulos, Jean Cappello, Julia I. Ellyard, Matthew Cook, Carola Vinuesa, Giles Walters, David A. Fulcher, Simon H. Jiang
Publikováno v:
Rheumatology & Autoimmunity. 3:15-25
Autor:
Julia I. Ellyard, Robert Tunningley, Ayla May Lorenzo, Simon H. Jiang, Amelia Cook, Rochna Chand, Dipti Talaulikar, Ann-Maree Hatch, Anastasia Wilson, Carola G. Vinuesa, Matthew C. Cook, David A. Fulcher
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Genetic primary immunodeficiency diseases are increasingly recognized, with pathogenic mutations changing the composition of circulating leukocyte subsets measured by flow cytometry (FCM). Discerning changes in multiple subpopulations is challenging,
Externí odkaz:
https://doaj.org/article/0b6ff66eb1ef4b62bb850289385bfead
Autor:
Guy J. M. Cameron, Kelly M. Cautivo, Svenja Loering, Simon H. Jiang, Aniruddh V. Deshpande, Paul S. Foster, Andrew N. J. McKenzie, Ari B. Molofsky, Philip M. Hansbro, Malcolm R. Starkey
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in perip
Externí odkaz:
https://doaj.org/article/c32c4a1093e346018910877cdb2a6ee4
Publikováno v:
Rheumatology & Autoimmunity. 1:40-51
Autor:
Greg Pratt, Bastien Llamas, Ruth M. Arkell, Shayne A. Bellingham, Cliff J Meldrum, Ravi Savarirayan, Lynette Russell, Alex Brown, Saul Newman, Carola G. Vinuesa, Hugh Dawkins, Shivashankar H. Nagaraj, Warren Kaplan, John Skinner, Ashley Farlow, Wendy E. Hoy, Simon Easteal, Hardip R. Patel, Graham J. Mann, Tom Calma, Kylie Gwynne, Misty R. Jenkins, Lyndon Ormond-Parker, Marcel E. Dinger, Jack Nunn, Rebekah McWhirter, Boe Rambaldini, Matthew Silcocks, Gareth Baynam, Matthew C. Cook, Michael S. Dobbie, Devashi Paliwal, Simon H Jiang, Stephen Leslie, Brendan J. McMorran, Neil Orr, Azure Hermes, Megan Davis, Yassine Souilmi, Renzo F. Balboa, Glenn Pearson
Publikováno v:
Am J Hum Genet
Expanded carrier screening (ECS) for recessive monogenic diseases requires prior knowledge of genomic variation, including DNA variants that cause disease. The composition of pathogenic variants differs greatly among human populations, but historical