Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Simon Geir, Møller"'
Autor:
Fatemeh Ghanavatinejad, Zahra Pourteymour Fard Tabrizi, Shadi Omidghaemi, Esmaeel Sharifi, Simon Geir Møller, Mohammad-Saeid Jami
Publikováno v:
Journal of Otology, Vol 14, Iss 3, Pp 77-88 (2019)
The utilization of biomarkers for in vivo and in vitro research is growing rapidly. This is mainly due to the enormous potential of biomarkers in evaluating molecular and cellular abnormalities in cell models and in tissue, and evaluating drug respon
Externí odkaz:
https://doaj.org/article/a269600c30de463aab9a97a9fe86cc52
Publikováno v:
Molecular Neurobiology
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of human COVID-19, not only causes flu-like symptoms and gut microbiome complications but a large number of infected individuals also experience a host of neurologi
Autor:
Ketan S Patil, Indranil Basak, Ramavati Pal, Hsin-Pin Ho, Guido Alves, Emmanuel J Chang, Jan Petter Larsen, Simon Geir Møller
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143969 (2015)
MicroRNAs are key regulators associated with numerous diseases. In HEK293 cells, miR-153-3p and miR-205-5p down-regulate alpha-synuclein (SNCA) and Leucine-rich repeat kinase 2 (LRRK2), two key proteins involved in Parkinson's disease (PD). We have u
Externí odkaz:
https://doaj.org/article/47693f0532ba4cca82c3c0fc99b7da5b
Autor:
Johannes Lange, Kristin Aaser Lunde, Camilla Sletten, Simon Geir Møller, Ole-Bjørn Tysnes, Guido Alves, Jan Petter Larsen, Jodi Maple-Grødem
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
Background. Parkinson’s disease (PD) and Alzheimer’s disease (AD) share pathological features, including amyloid-beta pathology. Amyloid-beta peptide is generated by sequential proteolysis of amyloid precursor protein (APP), and genetic variation
Externí odkaz:
https://doaj.org/article/7b9864cf9dd84e68b540b481b65b56e5
Publikováno v:
The New phytologistReferences. 154(3)
Phytochrome signal transduction has in the past often been viewed as being a nonspatially separated linear chain of events. However, through a combination of molecular, genetic and cell biological approaches, it is becoming increasingly evident that
Autor:
Fereshteh Ahmadinejad, Simon Geir Møller, Morteza Hashemzadeh-Chaleshtori, Gholamreza Bidkhori, Mohammad-Saeid Jami
Publikováno v:
Antioxidants, Vol 6, Iss 3, p 51 (2017)
Accumulating evidence shows that oxidative stress is involved in a wide variety of human diseases: rheumatoid arthritis, Alzheimer’s disease, Parkinson’s disease, cancers, etc. Here, we discuss the significance of oxidative conditions in differen
Externí odkaz:
https://doaj.org/article/c8a47e0f322744768b4b58b9559af7cd
Parkinson's disease is a progressive and irreversible neurodegenerative disorder associated with the selective loss of dopaminergic neurons and the presence of Lewy bodies. These intraneuronal protein aggregates are enriched in alpha-synuclein, a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713b0dfd3303348bfad8d9c422b2b239
https://doi.org/10.1016/b978-0-12-815950-7.00011-4
https://doi.org/10.1016/b978-0-12-815950-7.00011-4
Publikováno v:
Molecular Neurobiology. 56:3676-3689
The term proteostasis reflects the fine-tuned balance of cellular protein levels, mediated through a vast network of biochemical pathways. This requires the regulated control of protein folding, post-translational modification, and protein degradatio
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7662 (2009)
BACKGROUND:Iron-sulfur clusters are ubiquitous structures which act as prosthetic groups for numerous proteins involved in several fundamental biological processes including respiration and photosynthesis. Although simple in structure both the assemb
Externí odkaz:
https://doaj.org/article/4f2d8a91febf4cd08d3e99d2820b137b
Autor:
Hsin-Pin Ho, Esthelle Hoedt, Charalampos Tzoulis, Jan Petter Larsen, Ketan S. Patil, Thomas A. Neubert, Ramavati Pal, Rashed Abdullah, Sungsu Lee, Indranil Basak, Shubhangi Prabhudesai, Benjamin Rosen, Simon Geir Møller, Peter Yang, Keith Panick, Guido Alves, Emmanuel J. Chang
Publikováno v:
Molecular Neurobiology. 54:7639-7655
Parkinson's disease and other synucleinopathies are characterized by the presence of intra-neuronal protein aggregates enriched in the presynaptic protein α-synuclein. α-synuclein is considered an intrinsically disordered 14 kDa monomer, and althou