Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Simon Garinet"'
Autor:
Talal El Zarif, Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn, Pranshu Sahgal, Brad Fortunato, John Canniff, Amin H. Nassar, Sarah Abou Alaiwi, Ziad Bakouny, Gitanjali Lakshminarayanan, Hunter Savignano, Kevin Lyons, Sayed Matar, Atef Ali, Eddy Saad, Renee Maria Saliby, Paulo Cordeiro, Ziwei Zhang, Nourhan El Ahmar, Yasmin Nabil Laimon, Chris Labaki, Valisha Shah, Dory Freeman, Jillian O’Toole, Gwo-Shu Mary Lee, Justin Hwang, Mark Pomerantz, Sabina Signoretti, Eliezer M. Van Allen, Wanling Xie, Jacob E. Berchuck, Srinivas R. Viswanathan, David A. Braun, Toni K. Choueiri, Matthew L. Freedman, Sylvan C. Baca
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114350- (2024)
Summary: Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibitors (ICIs). Two major barriers to improving outcomes for sRCC are the limited understanding o
Externí odkaz:
https://doaj.org/article/a9e18e74ab10487c9c8418746dfe9c2a
Autor:
Simon Garinet, Audrey Didelot, Laetitia Marisa, Guillaume Beinse, Marine Sroussi, Françoise Le Pimpec-Barthes, Elizabeth Fabre, Laure Gibault, Pierre Laurent-Puig, Sophie Mouillet-Richard, Antoine Legras, Hélène Blons
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background In Lung adenocarcinoma (LUAD), targeted therapies and immunotherapies have moved from metastatic to early stage and stratification of the relapse risk becomes mandatory. Here we identified a miR-200 based RNA signature that deline
Externí odkaz:
https://doaj.org/article/904733005c644c07940174895ea01e79
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112978- (2023)
Summary: The success of precision oncology—which aims to match the right therapies to the right patients based on molecular status—is predicated on a robust pipeline of molecular targets against which therapies can be developed. Recent advances i
Externí odkaz:
https://doaj.org/article/e2a9b918547f404dbffa2454a9fc8ff9
Autor:
Rosa Montero-Macias, Meriem Koual, Céline Crespel, Marie Aude Le Frére-Belda, Hélène Blons Hélène, Huyen-Thu Nguyen-Xuan, Simon Garinet, Géraldine Perkins, Vincent Balay, Catherine Durdux, Marie Florin, Hélène Péré, Anne-Sophie Bats
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Abstract Background Homologous recombination deficiency is a marker of response to poly(ADP-ribose) polymerase inhibitors in different cancer types including ovary, prostate, and pancreatic cancer. To date, no report about poly(ADP-ribose) polymerase
Externí odkaz:
https://doaj.org/article/e2902d8aedda4ebd9459269035e8454a
Publikováno v:
Cancers, Vol 14, Iss 6, p 1400 (2022)
Lung cancer is the most common cause of cancer mortality worldwide, and non-small cell lung cancer (NSCLC) represents 80% of lung cancer subtypes. Patients with localized non-small cell lung cancer may be considered for upfront surgical treatment. Ho
Externí odkaz:
https://doaj.org/article/39224ca309d54a9ca0f6927ed7d7359e
Autor:
Coraline Dumenil, Jennifer Dumoulin, Violaine Giraud, Sylvie Labrune, Catherine Julie, Etienne Giroux Leprieur, Paul Takam Kamga, Adrien Costantini, Alexandre Corjon, Simon Garinet
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Despite prolonged tumor response to immune checkpoint inhibitors (ICIs) for a subset of patients with advanced non-small cell lung cancer (NSCLC), a secondary resistance will occur for a majority of these patients. The understanding of lat
Externí odkaz:
https://doaj.org/article/03dd415e5a6e46c3a728013a99b7763e
Autor:
Arnaud Bayle, Debora Basile, Simon Garinet, Bastien Rance, Pierre Laurent-Puig, Hélène Blons, Julien Taieb, Geraldine Perkins
Publikováno v:
Cancers, Vol 13, Iss 22, p 5750 (2021)
In digestive oncology, the clinical impact of targeted next-generation sequencing (NGS) in routine practice should be addressed. In this work, we studied the impact of a 22-gene NGS amplicon-based panel with Ion Torrent Proton Sequencing, prospective
Externí odkaz:
https://doaj.org/article/0b7ea37bfe5747a9b46149a9c8fd4522
Autor:
Emilie Moati, Valerie Taly, Simon Garinet, Audrey Didelot, Julien Taieb, Pierre Laurent-Puig, Aziz Zaanan
Publikováno v:
Cancers, Vol 13, Iss 19, p 4743 (2021)
Gastrointestinal (GI) cancers are major health burdens worldwide and biomarkers are needed to improve the management of these diseases along their evolution. Circulating tumor DNA (ctDNA) is a promising non-invasive blood and other bodily-fluid-based
Externí odkaz:
https://doaj.org/article/c38a04d73d04423f9b666178885efc89
Autor:
Guillaume Herbreteau, Fabrice Airaud, Elise Pierre-Noël, Audrey Vallée, Stéphane Bézieau, Sandrine Théoleyre, Hélène Blons, Simon Garinet, Marc Guillaume Denis
Publikováno v:
Cancers, Vol 13, Iss 16, p 4203 (2021)
Purpose: MEM is an NGS algorithm that uses Expectation-Maximisation to detect the presence of unstable alleles from the NGS sequences of five microsatellites (BAT-25, BAT-26, NR-21, NR-24 and NR-27). The purpose of this study was to compare the MEM a
Externí odkaz:
https://doaj.org/article/c10769702c864c7e8f7937a6f28d2948
Autor:
Sophie Vacher, Voreak Suybeng, Elodie Girard, Julien Masliah Planchon, Grégory Thomson, Constance Le Goux, Simon Garinet, Anne Schnitzler, Walid Chemlali, Virginie Firlej, Diane Damotte, Yves Allory, Maud Kamal, Géraldine Pignot, Ivan Bieche
Publikováno v:
Cancers, Vol 12, Iss 10, p 2882 (2020)
Numerous pan-genomic studies identified alterations in protein-coding genes and signaling pathways involved in bladder carcinogenesis, while non-coding somatic alterations remain weakly explored. The goal of this study was to identify clinical biomar
Externí odkaz:
https://doaj.org/article/a15dc50317e24823b275305eda57bc3a