Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Simon G Coetzee"'
Autor:
Dennis J Hazelett, Suhn Kyong Rhie, Malaina Gaddis, Chunli Yan, Daniel L Lakeland, Simon G Coetzee, Ellipse/GAME-ON consortium, Practical consortium, Brian E Henderson, Houtan Noushmehr, Wendy Cozen, Zsofia Kote-Jarai, Rosalind A Eeles, Douglas F Easton, Christopher A Haiman, Wange Lu, Peggy J Farnham, Gerhard A Coetzee
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004102 (2014)
Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics, but the causal links between increased genetic risk and onset/progression of disease processes remain to be identified. Here we report the first step in such an
Externí odkaz:
https://doaj.org/article/3a59b327630346c79a8646ea0eb44590
Autor:
Suhn Kyong Rhie, Simon G Coetzee, Houtan Noushmehr, Chunli Yan, Jae Mun Kim, Christopher A Haiman, Gerhard A Coetzee
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63925 (2013)
Breast Cancer (BCa) genome-wide association studies revealed allelic frequency differences between cases and controls at index single nucleotide polymorphisms (SNPs). To date, 71 loci have thus been identified and replicated. More than 320,000 SNPs a
Externí odkaz:
https://doaj.org/article/aac12c1ba1ce4bc4ad7fd157f9134c51
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
This file contains: Supplementary Figure 1 (Related to Figure 2): Haplotype frequency for tiles Enhancer Scanning times with multiple SNPs. Supplementary Figure 2 (Related to Figure 3): Conservation and S/MAR predicted sequences at the locus. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1e96b51e0effd40fb3fb0abf1b25d2
https://doi.org/10.1158/0008-5472.22423781.v1
https://doi.org/10.1158/0008-5472.22423781.v1
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
Genes selected for NanoString analysis. Contains the following tabs: (1) Nanostring gene set: final list for NanoString analysis. Gene Symbol, genes selected for nanostring analysis; Pathway, annotation from literature or from pathways in Tab 10; Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113c54ca5d3c2e82683f9df1b70ff5b7
https://doi.org/10.1158/0008-5472.22423775
https://doi.org/10.1158/0008-5472.22423775
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
Genome-wide association studies have identified 40 ovarian cancer risk loci. However, the mechanisms underlying these associations remain elusive. In this study, we conducted a two-pronged approach to identify candidate causal SNPs and assess underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b08dbffe9e10fdd659dbb2388969f4
https://doi.org/10.1158/0008-5472.c.6511577.v1
https://doi.org/10.1158/0008-5472.c.6511577.v1
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
Primers used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6486bf9e32aee233700cf7ae85691703
https://doi.org/10.1158/0008-5472.22423778.v1
https://doi.org/10.1158/0008-5472.22423778.v1
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
Fine mapping association results. Contains univariate and conditional (conditioning on rs3814113) analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5de97353365edbd6882e105879cfaab
https://doi.org/10.1158/0008-5472.22423769.v1
https://doi.org/10.1158/0008-5472.22423769.v1
Autor:
Alvaro N.A. Monteiro, Simon A. Gayther, Paul D. Pharoah, Ellen L. Goode, Thomas A. Sellers, Timothy R. Hughes, Houtan Noushmehr, Gerhard A. Coetzee, Catherine M. Phelan, Susan J. Ramus, Georgia Chenevix-Trench, Harvey Risch, Sean J. Yoder, Madalene A. Earp, Ally W. Yang, Howard C. Shen, Simon G. Coetzee, Paulo C. Lyra, Renato S. Carvalho, Anxhela Gjyshi, Hamed S. Najafabadi, Dennis J. Hazelett, Kate Lawrenson, Gustavo Mendoza-Fandiño, Jonathan P. Tyrer, Nicholas T. Woods, Melissa A. Buckley
List of 134 SNPs in linkage disequilibrium (r2 {greater than or equal to} 0.3) with rs3814113 (based on 1000GP v3), selected for functional analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b123af7b0a8eaafb925142f9530b01e1
https://doi.org/10.1158/0008-5472.22423772
https://doi.org/10.1158/0008-5472.22423772
Autor:
Eva Biener-Ramanujan, Florian Rosier, Simon G. Coetzee, Dermot D. P. McGovern, Dennis Hazelett, Stephan R. Targan, Rivkah Gonsky
Publikováno v:
Frontiers in Immunology. 13
Ribonuclease T2 gene (RNASET2) variants are associated in genome wide association studies (GWAS) with risk for several autoimmune diseases, including Crohn’s disease (CD). In T cells, a functional and biological relationship exists between TNFSF15-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033283ffe7d960866b418eee86bc008b
https://doi.org/10.3389/fimmu.2022.999155
https://doi.org/10.3389/fimmu.2022.999155
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103084-(2021)
iScience, Vol 24, Iss 10, Pp 103084-(2021)
Summary Cancer is an organism-level disease, impacting processes from cellular metabolism and the microenvironment to systemic immune response. Nevertheless, efforts to distinguish overarching mutational processes from interactions with the cell of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9db80c2503769a1ff2c92b4d395e49
http://europepmc.org/articles/PMC8477189
http://europepmc.org/articles/PMC8477189