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Akademický článek

Glucose-1,6-Bisphosphate, a Key Metabolic Regulator, Is Synthesized by a Distinct Family of α-Phosphohexomutases Widely Distributed in Prokaryotes

Autor: Niels Neumann, Simon Friz, Karl Forchhammer

Publikováno v: mBio, Vol 13, Iss 4 (2022)

ABSTRACT The reactions of α-d-phosphohexomutases (αPHM) are ubiquitous, key to primary metabolism, and essential for several processes in all domains of life. The functionality of these enzymes relies on an initial phosphorylation step which requir

Externí odkaz: https://doaj.org/article/94a8e07d81894451acf99e5035316360

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Metabolization of α-D-carba-glucosamine in vivo generates antimetabolites of cell wall precursors

Autor: Milena Mund, Simon Friz, Anna Esser, Daniel Matzner, Alexander Babczyk, Dirk Menche, Heike Brötz-Oesterhelt, Christoph Mayer, Günter Mayer

α-D-Carba-glucosamine (CGlcN) is a carbocyclic analog of α-D-glucosamine that inhibits growth ofBacillus subtilisandStaphylococcus aureus. CGlcN is internalized and concomitantly phosphorylated via the phosphotransferase system yielding α-D-carba-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dfc0cc05bc1ae14ec3c84107899552f
https://doi.org/10.1101/2023.02.08.527593

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Glucose-1,6-Bisphosphate, a Key Metabolic Regulator, Is Synthesized by a Distinct Family of α-Phosphohexomutases Widely Distributed in Prokaryotes

Autor: Karl Forchhammer, Simon Friz, Niels Neumann

Publikováno v: mBio. 13

The reactions of α-D-phosphohexomutases (αPHM) are ubiquitous, key to primary metabolism and essential for several processes in all domains of life. The functionality of these enzymes relies on an initial auto-phosphorylation step which requires th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4b7c2144479e983a09eb85e65e249c
https://doi.org/10.1128/mbio.01469-22

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The TonB-dependent uptake of pyrroloquinoline-quinone (PQQ) and secretion of gluconate by Escherichia coli K-12

Autor: Klaus Hantke, Simon Friz

Publikováno v: Molecular microbiologyREFERENCES. 118(4)

Glucose is taken up by Escherichia coli through the phosphotransferase system (PTS) as the preferred carbon source. PTS mutants grow with glucose as a carbon source only in the presence of pyrroloquinoline quinone (PQQ), which is needed as a redox co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dff9c734402f40728894400490646f
https://pubmed.ncbi.nlm.nih.gov/36054785

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Chitin, Chitin Oligosaccharide, and Chitin Disaccharide Metabolism of Escherichia coli Revisited: Reassignment of the Roles of ChiA, ChbR, ChbF, and ChbG

Autor: Christoph Mayer, Axel Walter, Simon Friz

Publikováno v: Microbial Physiology. 31:178-194

Escherichia coli is unable to grow on polymeric and oligomeric chitin, but grows on chitin disaccharide (GlcNAc-GlcNAc; N,N′-diacetylchitobiose) and chitin trisaccharide (GlcNAc-GlcNAc-GlcNAc; N,N′,N′′-triacetylchitotriose) via expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0be22dc3b0f197942dfcd6f7d6ae680f
https://doi.org/10.1159/000515178

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Chitin, Chitin Oligosaccharide, and Chitin Disaccharide Metabolism of Escherichia coli Revisited: Reassignment of the Roles of ChiA, ChbR, ChbF, and ChbG

Autor: Axel, Walter, Simon, Friz, Christoph, Mayer

Publikováno v: Microbial physiology. 31(2)

Escherichia coli is unable to grow on polymeric and oligomeric chitin, but grows on chitin disaccharide (GlcNAc-GlcNAc; N,N'-diacetylchitobiose) and chitin trisaccharide (GlcNAc-GlcNAc-GlcNAc; N,N',N''-triacetylchitotriose) via expression of the chb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ff6af4dc13250ec7b6b55522b4e1a8b
https://pubmed.ncbi.nlm.nih.gov/33794535

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Elektronická kniha

Sicherheit für Versammlungsstätten und Veranstaltungen : Ein umfassendes Handbuch zur Sicherheitskonzeption

Autor: Stephan Gundel, Heinz Wilhelm Bartling, Günther Epple, Christian Falk, Simon Friz, Achim Hecker, Norbert Honisch, Dominique Huber, Torsten Juds, Matthias Link, Arndt Malyska, Mandy Risch-Kerst, Lucien Schibli, Daniel Schlatter, Peter Surbeck, Christoph Vahlhaus, Diana Weise

Sicherheit ist oberstes Gebot Die Gewährleistung der Sicherheit für Versammlungsstätten und Veranstaltungen ist eine anspruchsvolle und vielschichtige Aufgabe. Welche Risiken sind zu beachten, welche Schutzziele adäquat? Welches Regelwerk ist tat

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