Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Simon Früh"'
Autor:
Stephanie Niklaus, Stella M. K. Glasauer, Peter Kovermann, Kulsum F. Farshori, Lucia Cadetti, Simon Früh, Nicolas N. Rieser, Matthias Gesemann, Jingjing Zang, Christoph Fahlke, Stephan C. F. Neuhauss
Publikováno v:
Open Biology, Vol 14, Iss 7 (2024)
In the central nervous system of vertebrates, glutamate serves as the primary excitatory neurotransmitter. However, in the retina, glutamate released from photoreceptors causes hyperpolarization in post-synaptic ON-bipolar cells through a glutamate-g
Externí odkaz:
https://doaj.org/article/865a9d9b0c7d4231b313d2574304693f
Autor:
Noa Bielopolski, Michal Stawarski, Ilana Roitman, Karen Fridman, Shane Wald-Altman, Simon Früh, Bernhard Bettler, Andreea Nissenkorn
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
GABAB receptors (GABABRs) are G protein-coupled receptors for γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Pathogenic variants in the GABBR1 and GABBR2 genes, which encode the GB1 and GB2 subunits
Externí odkaz:
https://doaj.org/article/6104369c0098470197d3f546a913242f
Autor:
Antonella Samoggia, Anagnostis Argiriou, Ioannis Mallidis, Simon Früh, Zeynep Beyhan, Andrea Fantini, Tamara Ettinger, Evangelia Mouchtaropoulou, Amine M. Benmehaia, Leonidas Parodos, Andrea Gianotti, Lofti Archour, Adnen Kacem, Georgia Ayfantopoulou
Publikováno v:
Frontiers in Sustainable Food Systems, Vol 7 (2023)
Fairness and ethical values in agro-food chain lay at the center of the current debate on agro-food chain sustainability. The food labels may contain elements focused on agro-food chain management fairness practices. The objective of the present stud
Externí odkaz:
https://doaj.org/article/7308df77be8a43f59985267950a761da
Autor:
Margarita C. Dinamarca, Adi Raveh, Andy Schneider, Thorsten Fritzius, Simon Früh, Pascal D. Rem, Michal Stawarski, Txomin Lalanne, Rostislav Turecek, Myeongjeong Choo, Valérie Besseyrias, Wolfgang Bildl, Detlef Bentrop, Matthias Staufenbiel, Martin Gassmann, Bernd Fakler, Jochen Schwenk, Bernhard Bettler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The mechanisms that control the presynaptic abundance of GABAB receptors (GBRs) remains unclear. This study shows that sequence-related epitopes in APP, AJAP-1 and PIANP bind with nanomolar affinities to the N-terminal sushi-domain of presynaptic GBR
Externí odkaz:
https://doaj.org/article/1122aad37c3e4affaea79ae9d7612a6d
Autor:
Stephanie Niklaus, Stella M.K. Glasauer, Peter Kovermann, Kulsum F. Farshori, Lucia Cadetti, Simon Früh, Nicolas N. Rieser, Matthias Gesemann, Christoph Fahlke, Stephan C.F. Neuhauss
In the central nervous system of vertebrates, glutamate serves as the primary excitatory neurotransmitter. However, in the retina, glutamate released from photoreceptors causes hyperpolarization in postsynaptic ON-bipolar cells through a glutamate-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010987db56cdca0522516e138a7c115c
https://doi.org/10.1101/2023.05.01.538911
https://doi.org/10.1101/2023.05.01.538911
Autor:
Claire de Groot, Amalia Floriou-Servou, Yuan-Chen Tsai, Simon Früh, Manuela Kohler, Georgia Parkin, Cornelia Schwerdel, Giovanna Bosshard, Kai Kaila, Jean-Marc Fritschy, Shiva K Tyagarajan
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007073 (2017)
In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic syna
Externí odkaz:
https://doaj.org/article/7cb2b632fcce41a0b646288801f9b475
Autor:
Carsten Sticht, Bernd Arnold, Thomas Enkel, Cyrill Géraud, Siladitta Biswas, Moritz Küchler, Sergij Goerdt, Manuel Winkler, Myeongjeong Choo, Bernhard Bettler, Stefan M. Berger, Dorde Komljenovic, Dusan Bartsch, Oliver von Bohlen und Halbach, Simon Früh, Laurens Preisendörfer, Pascal D. Rem
Publikováno v:
Molecular Psychiatry
Pianp (also known as Leda-1) is a type I transmembrane protein with preferential expression in the mammalian CNS. Its processing is characterized by proteolytic cleavage by a range of proteases including Adam10, Adam17, MMPs, and the γ-secretase com
Autor:
Shiva K. Tyagarajan, Giovanna Bosshard, Benjamin F. N. Campbell, Jean-Marc Fritschy, Simon Früh
Publikováno v:
Journal of Neurochemistry. 147:477-494
In dissociated neuronal cultures the absence of spatial and temporal cues causes the emergence of mismatched synapses, where post-synaptic proteins of GABAergic synapses are in part apposed to glutamatergic pre-synaptic terminals and vice versa. This
Autor:
Rocío Alfaro-Ruiz, Alain Buisson, Luis de la Ossa, Bernhard Bettler, Rafael Luján, Simon Früh, Alejandro Martín-Belmonte, Ryuichi Shigemoto, Ana Esther Moreno-Martínez, José L. Martínez-Hernández, Yugo Fukazawa, Carolina Aguado
Publikováno v:
RUIdeRA. Repositorio Institucional de la UCLM
instname
instname
The hippocampus plays key roles in learning and memory and is a main target of Alzheimer’s disease (AD), which causes progressive memory impairments. Despite numerous investigations about the processes required for the normal hippocampal functions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d35027757a24d59523ebc8ba0db96fa
http://hdl.handle.net/10578/23760
http://hdl.handle.net/10578/23760
Autor:
Simon Früh, Mirko Santello, Jennifer Romanos, Shiva K. Tyagarajan, Patrizia Panzanelli, Daniela Bürgisser, Kevin P. Campbell, Jean-Marc Fritschy
Publikováno v:
Journal of Neuroscience
Distinct types of GABAergic interneurons target different subcellular domains of pyramidal cells, thereby shaping pyramidal cell activity patterns. Whether the presynaptic heterogeneity of GABAergic innervation is mirrored by specific postsynaptic fa