Identifying key priorities for research to protect the consumer with food hypersensitivity:a UK Food Standards Agency Priority Setting Exercise

Autor: Paul Turner, Katherine Cowan, Lynne Regent, Alexa Baracaia, Karen Brunas, Rebecca Knibb, Stella Cochrane, Rachel K. Ward, Elizabeth Andoh-Kesson, C. H. Chan, Mary Feeney, Heidi Urwin, Simon Flanagan, Michael Walker, Ian Kimber, Matthew J Ridd, Adam T. Fox, Carina Venter, Darryl Thomson, Maggie Young, Kirsty Langford, Graham Roberts, Leigh George, John O'Brien, Sarah Stoneham, Christina Heeley, M. Hazel Gowland, Alisha Barfield, Sarah Baker, Guy Scadding, Adrian Rogers, Alan R. Mackie, Ross A.R. Yarham, Tim McLachlan, Julie Barnett

Publikováno v: Turner, P J, Ridd, M J, O'Brien, J & al., E 2021, ' Identifying key priorities for research to protect the consumer with food hypersensitivity : A UK Food Standards Agency Priority Setting Exercise ', Clinical and Experimental Allergy, vol. 51, no. 10, pp. 1322-1330 . https://doi.org/10.1111/cea.13983
Turner, P J, Andoh-Kesson, E, Baker, S, Baracaia, A, Barfield, A, Barnett, J, Brunas, K, Chan, C-H, Cochrane, S, Cowan, K, Feeney, M, Flanagan, S, Fox, A, George, L, Gowland, M H, Heeley, C, Kimber, I, Knibb, R, Langford, K, Mackie, A, McLachlan, T, Regent, L, Ridd, M, Roberts, G, Rogers, A, Scadding, G, Stoneham, S, Thomson, D, Urwin, H, Venter, C, Walker, M, Ward, R, Yarham, R, Young, M & O'Brien, J 2021, ' Identifying key priorities for research to protect the consumer with food hypersensitivity : a UK Food Standards Agency Priority Setting Exercise ', Clinical and Experimental Allergy, vol. 51, no. 10, pp. 1322-1330 . https://doi.org/10.1111/cea.13983

Introduction\ud \ud Food hypersensitivity (FHS), including food allergy, coeliac disease and food intolerance, is a major public health issue. The Food Standards Agency (FSA), an independent UK Government department working to protect public health a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107a346e15f9d3cec8179db446eba317
https://publications.aston.ac.uk/id/eprint/42873/6/cea.13983.pdf

Are current analytical methods suitable to verify VITAL® 2.0/3.0 allergen reference doses for EU allergens in foods?

Autor: Michela Miani, Marie-Claude Robert, Joana Costa, Thomas Holzhauser, Martin Röder, Francesca Lambertini, Simon Flanagan, Gavin O'Connor, Zsuzsanna Bugyi, Barbara J. Hirst, Stefan Ronsmans, Christiane Kruse Fæste, James P. Hindley, Philip E. Johnson, Chun Han Chan, Sándor Tömösközi

Publikováno v: Food and chemical toxicology, 145:111709

Food allergy affects up to 6% of Europeans. Allergen identification is important for the risk assessment and management of the inadvertent presence of allergens in foods. The VITAL® initiative for voluntary incidental trace allergen labeling suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435dd16ca41ac029690d999876977e24
https://pubmed.ncbi.nlm.nih.gov/32866515

Expanding the spectrum of IDH1 mutations in gliomas

Autor: Simon Flanagan, Ruta Gupta, Maggie Lee, Michael E. Buckland, Brindha Shivalingham, Cheryl C. Y. Li, Helen Wheeler, Sanaz Maleki

Publikováno v: Modern Pathology. 26:619-625

Mutations in isocitrate dehydrogenase -1 or -2 (IDH1 or IDH2) are found in the majority of WHO grade II and III diffuse gliomas and secondary glioblastomas. IDH mutation screening is rapidly becoming part of the routine pathological work up of human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4607555f7aac5ae8751bef5d408502a6
https://doi.org/10.1038/modpathol.2012.210

Somatic and germline mosaicism for a R248C missense mutation inFGFR3, resulting in a skeletal dysplasia distinct from thanatophoric dysplasia

Autor: John Masel, Simon Flanagan, Mark Hayes, Ian A. Glass, Ravi Savarirayan, Tony Roscioli, V.J. Hyland, Stephen P. Robertson

Publikováno v: American Journal of Medical Genetics. :157-168

In this communication, we report the identification of a mosaic R248C missense mutation in the IgII-III linker region of the gene encoding the fibroblast growth factor receptor-3 (FGFR3), in an individual who manifests a skeletal dysplasia and epider

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ab53a653d90f87d9c4963ee2f9e8a3
https://doi.org/10.1002/ajmg.a.20012

Promoter Methylation Analysis of IDH Genes in Human Gliomas

Autor: Cheryl C. Y. Li, Simon Flanagan, Michael E. Buckland, Maggie Lee, Catherine M. Suter

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 2 (2012)

Mutations in isocitrate dehydrogenase (IDH) -1 or -2 are found in the majority of WHO grade II and III astrocytomas and oligodendrogliomas, and secondary glioblastomas. Almost all described mutations are heterozygous missense mutations affecting a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1616146c33a207fa299fcb6c5cef170