Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Simon Fishilevich"'
Autor:
Dvir Dahary, Yaron Golan, Yaron Mazor, Ofer Zelig, Ruth Barshir, Michal Twik, Tsippi Iny Stein, Guy Rosner, Revital Kariv, Fei Chen, Qiang Zhang, Yiping Shen, Marilyn Safran, Doron Lancet, Simon Fishilevich
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Background The clinical genetics revolution ushers in great opportunities, accompanied by significant challenges. The fundamental mission in clinical genetics is to analyze genomes, and to identify the most relevant genetic variations underl
Externí odkaz:
https://doaj.org/article/4b87794257854274bfbe57b3b3799db9
Autor:
Johnathan Cooper-Knock, Sai Zhang, Kevin P. Kenna, Tobias Moll, John P. Franklin, Samantha Allen, Helia Ghahremani Nezhad, Alfredo Iacoangeli, Nancy Y. Yacovzada, Chen Eitan, Eran Hornstein, Eran Ehilak, Petra Celadova, Daniel Bose, Sali Farhan, Simon Fishilevich, Doron Lancet, Karen E. Morrison, Christopher E. Shaw, Ammar Al-Chalabi, Jan H. Veldink, Janine Kirby, Michael P. Snyder, Pamela J. Shaw, Ian Blair, Naomi Wray, Matthew Kiernan, Miguel Mitne Neto, Adriano Chio, Ruben Cauchi, Wim Robberecht, Philip van Damme, Phillippe Corcia, Phillipe Couratier, Orla Hardiman, Russel McLaughlin, Marc Gotkine, Vivan Drory, Nicola Ticozzi, Vincenzo Silani, Jan Veldink, Leonard van den Berg, Mamede de Carvalho, Jesus Mora Pardina, Monica Povedano, Peter Andersen, Markus Wber, Nazli Başak, Christopher Shaw, Pamela Shaw, Karen Morrison, John Landers, Jonathan Glass
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108456- (2020)
Summary: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vi
Externí odkaz:
https://doaj.org/article/7fac5ebf332545088de18b27ea1f88df
Autor:
Yunpeng Wang, Ron Nudel, Michael E Benros, Kristin Skogstrand, Simon Fishilevich, iPSYCH-BROAD, Doron Lancet, Jiangming Sun, David M Hougaard, Ole A Andreassen, Preben Bo Mortensen, Alfonso Buil, Thomas F Hansen, Wesley K Thompson, Thomas Werge
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009163 (2020)
Circulating inflammatory markers are essential to human health and disease, and they are often dysregulated or malfunctioning in cancers as well as in cardiovascular, metabolic, immunologic and neuropsychiatric disorders. However, the genetic contrib
Externí odkaz:
https://doaj.org/article/c0ba03a547c14e899fd13b9c066cc5e1
Autor:
Noa Rappaport, Simon Fishilevich, Ron Nudel, Michal Twik, Frida Belinky, Inbar Plaschkes, Tsippi Iny Stein, Dana Cohen, Danit Oz-Levi, Marilyn Safran, Doron Lancet
Publikováno v:
BioMedical Engineering OnLine, Vol 16, Iss S1, Pp 1-14 (2017)
Abstract Background A key challenge in the realm of human disease research is next generation sequencing (NGS) interpretation, whereby identified filtered variant-harboring genes are associated with a patient’s disease phenotypes. This necessitates
Externí odkaz:
https://doaj.org/article/fde3297c5a974cf4b96c55ac194f83d5
Autor:
Nava Reznik, Annastassia D. Gallo, Katherine W. Rush, Gabriel Javitt, Yael Fridmann-Sirkis, Tal Ilani, Noa A. Nairner, Simon Fishilevich, David Gokhman, Kelly N. Chacón, Katherine J. Franz, Deborah Fass
Publikováno v:
Cell. 185(22)
Mucus protects the epithelial cells of the digestive and respiratory tracts from pathogens and other hazards. Progress in determining the molecular mechanisms of mucus barrier function has been limited by the lack of high-resolution structural inform
Autor:
Alex Bateman, Dimitra Karagkouni, Robin R. Gutell, Lina Ma, Ruth C. Lovering, Prita Mani, Artemis G. Hatzigeorgiou, Pieter-Jan Volders, Elspeth A. Bruford, Simon Kay, Kevin J. Peterson, Lauren M. Lui, Steven J Marygold, Todd M. Lowe, Jamie J. Cannone, Anton S. Petrov, Patricia P. Chan, Robert D. Finn, Adam Frankish, Stefan E. Seemann, David Hoksza, Bastian Fromm, Ioanna Kalvari, Maciej Szymanski, Ruth L. Seal, Ruth Barshir, Pieter Mestdagh, Simona Panni, Carlos Eduardo Ribas, Michelle S. Scott, Pablo Porras, Simon Fishilevich, Anton I. Petrov, Sam Griffiths-Jones, Blake A. Sweeney, Zhang Zhang, Jonathan M. Mudge, Zasha Weinberg, Sridhar Ramachandran, Jan Gorodkin, Shuai Weng, Eric P. Nawrocki, Wojciech M. Karlowski, Barbara Kramarz, Philia Bouchard-Bourelle, Gil dos Santos
Publikováno v:
Sweeney, B A, Petrov, A I, Ribas, C E, Finn, R D, Bateman, A, Szymanski, M, Karlowski, W M, Seemann, S E, Gorodkin, J, Cannone, J J, Gutell, R R, Kay, S, Marygold, S, Dos Santos, G, Frankish, A, Mudge, J M, Barshir, R, Fishilevich, S, Chan, P P, Lowe, T M, Seal, R, Bruford, E, Panni, S, Porras, P, Karagkouni, D, Hatzigeorgiou, A G, Ma, L, Zhang, Z, Volders, P J, Mestdagh, P, Griffiths-Jones, S, Fromm, B, Peterson, K J, Kalvari, I, Nawrocki, E P, Petrov, A S, Weng, S, Bouchard-Bourelle, P, Scott, M, Lui, L M, Hoksza, D, Lovering, R C, Kramarz, B, Mani, P, Ramachandran, S & Weinberg, Z 2021, ' RNAcentral 2021 : Secondary structure integration, improved sequence search and new member databases ', Nucleic Acids Research, vol. 49, no. D1, pp. D212-D220 . https://doi.org/10.1093/nar/gkaa921
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that provides a single access point to 44 RNA resources and >18 million ncRNA sequences from a wide range of organisms and RNA types. RNAcentral now also includes secondary (2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e19e03b750a9a147992e2137ae30e05
https://curis.ku.dk/ws/files/259671035/gkaa921.pdf
https://curis.ku.dk/ws/files/259671035/gkaa921.pdf
Autor:
Marilyn Safran, Naomi Rosen, Michal Twik, Ruth BarShir, Tsippi Iny Stein, Dvir Dahary, Simon Fishilevich, Doron Lancet
Publikováno v:
Practical Guide to Life Science Databases ISBN: 9789811658112
The GeneCards® database of human genes was launched in 1997 and has expanded since then to encompass gene-centric, disease-centric, and pathway-centric entities and relationships within the GeneCards Suite, effectively navigating the universe of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c84636efd45890b393c251b7a46d6c
https://doi.org/10.1007/978-981-16-5812-9_2
https://doi.org/10.1007/978-981-16-5812-9_2
Autor:
Ron Nudel, Jiangming Sun, Wesley K. Thompson, Yunpeng Wang, Doron Lancet, Preben Bo Mortensen, Thomas Werge, Alfonso Buil, Thomas Hansen, David M. Hougaard, Michael E. Benros, Ole A. Andreassen, Kristin Skogstrand, iPSYCH-BROAD, Simon Fishilevich
Publikováno v:
PLoS Genetics
Wang, Y, Nudel, R, Benros, M E, Skogstrand, K, Fishilevich, S, iPSYCH-BROAD, Lancet, D, Sun, J, Hougaard, D M, Andreassen, O A, Mortensen, P B, Buil, A, Hansen, T F, Thompson, W K & Werge, T 2020, ' Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth ', PLOS Genetics, vol. 16, no. 11, e1009163 . https://doi.org/10.1371/journal.pgen.1009163
PLoS Genetics, Vol 16, Iss 11, p e1009163 (2020)
Wang, Y, Nudel, R, Benros, M E, Skogstrand, K, Fishilevich, S, Lancet, D, Sun, J, Hougaard, D M, Andreassen, O A, Mortensen, P B, Buil, A, Hansen, T F, Thompson, W K, Werge, T & iPSYCH-BROAD 2020, ' Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth ', PLOS Genetics, vol. 16, no. 11, e1009163 . https://doi.org/10.1371/journal.pgen.1009163
Wang, Y, Nudel, R, Benros, M E, Skogstrand, K, Fishilevich, S, iPSYCH-BROAD, Lancet, D, Sun, J, Hougaard, D M, Andreassen, O A, Mortensen, P B, Buil, A, Hansen, T F, Thompson, W K & Werge, T 2020, ' Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth ', PLOS Genetics, vol. 16, no. 11, e1009163 . https://doi.org/10.1371/journal.pgen.1009163
PLoS Genetics, Vol 16, Iss 11, p e1009163 (2020)
Wang, Y, Nudel, R, Benros, M E, Skogstrand, K, Fishilevich, S, Lancet, D, Sun, J, Hougaard, D M, Andreassen, O A, Mortensen, P B, Buil, A, Hansen, T F, Thompson, W K, Werge, T & iPSYCH-BROAD 2020, ' Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth ', PLOS Genetics, vol. 16, no. 11, e1009163 . https://doi.org/10.1371/journal.pgen.1009163
Circulating inflammatory markers are essential to human health and disease, and they are often dysregulated or malfunctioning in cancers as well as in cardiovascular, metabolic, immunologic and neuropsychiatric disorders. However, the genetic contrib
Autor:
Johnathan Cooper-Knock, Sai Zhang, Kevin P. Kenna, Tobias Moll, John Franklin, Samantha Allen, Helia Ghahremani Nezhad, Nancy S. Yacovzada, Chen Eitan, Eran Hornstein, Eran Ehilak, Petra Celadova, Daniel Bose, Sali MK Farhan, Simon Fishilevich, Doron Lancet, Karen E. Morrison, Chris Shaw, Ammar Al-Chalabi, Project MinE ALS Sequencing Consortium, Jan H. Veldink, Janine Kirby, Michael P. Snyder, Pamela J. Shaw
Publikováno v:
SSRN Electronic Journal.
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organise membrane lipid rafts (MLR) important for cell signalling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. Genom
Autor:
Doron Lancet, Dvir Dahary, Tsippi Iny Stein, Ofer Zelig, Ruth Barshir, Marilyn Safran, Yaron Mazor, Fei Chen, Guy Rosner, Yiping Shen, Michal Twik, Yaron Golan, Revital Kariv, Simon Fishilevich, Qiang Zhang
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-17 (2019)
BMC Medical Genomics
BMC Medical Genomics
BackgroundThe clinical genetics revolution ushers in great opportunities, accompanied by significant challenges. The fundamental mission in clinical genetics is to analyze genomes, and to identify the most relevant genetic variations underlying a pat