Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Simon Fisher"'
Autor:
Craig K. Docherty, Nina Denver, Simon Fisher, Margaret Nilsen, Dianne Hillyard, Rebecca L. Openshaw, Hicham Labazi, Margaret R. MacLean
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 396-405 (2020)
The 5HT1B receptor (5HT1BR) contributes to the pathogenic effects of serotonin in pulmonary arterial hypertension. Here, we determine the effect of a microRNA96 (miR96) mimic delivered directly to the lungs on development of severe pulmonary hyperten
Externí odkaz:
https://doaj.org/article/e5d263e8dc1b4639b7c47108893f55bc
Publikováno v:
Diabetes. 71
Several clinical trials have noted an association between hypoglycemia and major cardiovascular events; however, a direct link between antecedent hypoglycemia and worse cardiac outcomes has not been established. We hypothesized that antecedent recurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1a460fca3996e0ea0e7dae179d0a1b7
https://doi.org/10.2337/db22-231-or
https://doi.org/10.2337/db22-231-or
Publikováno v:
Diabetes. 71
To test the hypothesis that metoclopramide (a dopamine antagonist) may restore hypoglycemic counterregulation, 10-week old rats underwent recurrent (insulin-induced) hypoglycemia (RH) to induce a blunted sympathoadrenal response. RH rats were treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268f427af7e1b88c3fa4c5bdb7124368
https://doi.org/10.2337/db22-164-or
https://doi.org/10.2337/db22-164-or
Autor:
MATTHEW WAHL, RABIA KIANI, JULIE NEUBERGER, BONNIE WILSON, MARY ELIZABETH HARTNETT, SIMON FISHER
Publikováno v:
Diabetes. 71
Point-of-care retinal imaging is effective at identifying diabetic retinopathy. However, appropriate follow-up, referral, and access to specialized eye care remains a barrier for the treatment of identified eye disease. We tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a964ab3c626581f2a108b313068ec0
https://doi.org/10.2337/db22-48-or
https://doi.org/10.2337/db22-48-or
Publikováno v:
European Neuropsychopharmacology. 63:e57-e58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2cd7e87602376439381cd5fbd16ce8e
https://doi.org/10.1016/j.euroneuro.2022.07.114
https://doi.org/10.1016/j.euroneuro.2022.07.114
Autor:
Amirhossein Modabbernia, Didac Vidal-Pineiro, Ingrid Agartz, Ole Andreassen, Rosa Ayesa-Arriola, Alessandro Bertolino, D Boomsma, Josiane Bourque, Alan Breier, Henry Brodaty, Rachel Brouwer, Jan Buitelaar, Erick Canales-Rodriguez, Xavier Caseras, Patricia Conrod, Benedicto Crespo-Facorro, Fabrice Crivello, Eveline Crone, Greig De Zubicaray, Erin Dickie, Danai Dima, Thomas Espeseth, Stefan Frenzel, Simon Fisher, Barbara Franke, David Glahn, Hans Grabe, Dominik Grotegerd, Oliver Gruber, Amalia Guerrero-Pedraza, Raquel Gur, Ruben Gur, Catharina Hartman, Pieter Hoekstra, Hilleke Hulshoff Pol, Neda Jahanshad, Terry Jernigan, Jiyang Jiang, Andrew Kalnin, Nicole Kochan, Bernard Mazoyer, Brenna McDonald, Katie McMahon, Lars Nyberg, Jaap Oosterlaan, E Pomarol-Clotet, Joaquim Radua, Joshua Roffman, Perminder Sachdev, Theodore Satterthwaite, Raymond Salvador, Salvador Sarró, Andrew Saykin, Gunter Schumann, Jordan Smoller, Iris Sommer, Christian Tamnes, Sophia Thomopoulos, Julian Trollor, Dennis van 't Ent, Aristotle Voineskos, Yang Wang, Bernd Weber, Wei Wen, Lars T. Westlye, Heather Whalley, Lara wierenga, Steven Williams, Katharina Wittfeld, Margaret Wright, Paul Thompson, Tomas Paus, Sophia Frangou
Mechanisms underpinning neurotypical age-related variations in cortical thickness in the human brain remain insufficiently specified. Here we used cell-specific marker genes, followed by gene ontology and enrichment analyses, to quantify the associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::100cbe1a960cc95ab75fb0b263efd9be
https://doi.org/10.21203/rs.3.rs-1686228/v1
https://doi.org/10.21203/rs.3.rs-1686228/v1
Autor:
Filippo Abbondanza, Philip Dale, Carol Wang, Marianna E. Hayiou-Thomas, Umar Toseeb, Tanner koomar, Karen Wigg, Yu Feng, Kaitlyn M Price, Elizabeth Kerr, Sharon Guger, Maureen Lovett, Lisa J Strug, Elsje van Bergen, Conor V. Dolan, Bruce Tomblin, Kristina Moll, Gerd Schulte-Körne, Nina Neuhoff, Andreas Warnke, Simon Fisher, Cathy L Barr, Jacob J Michaelson, Dorret Boomsma, Margaret J. Snowling, Charles Hulme, Andrew Whitehouse, Craig E Pennell, Dianne Newbury, John Frederick Stein, Joel B Talcott, Dorothy Vera Margaret Bishop, Silvia Paracchini
Worldwide, the majority of people prefer using the right hand for most motor tasks, including writing. Because of the link between handedness and language hemispheric dominance, handedness has been studied for association with language-related disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b218d5ac0c667ec4440675642cf47dd
https://doi.org/10.31234/osf.io/74jsd
https://doi.org/10.31234/osf.io/74jsd
Autor:
Michael Bettess, Simon Fisher, James S. Rush, Christopher Davis, Ian H. Frazer, Jonathan B. Baell, Michael P. Brown, Mark Sullivan, Michael P. Jennings, Michael A. McGuckin, Eloise Keeffe, Craig Rayner, Anand Gautam, Philip Kearney, C. Glenn Begley, Brett Carter, William N. Charman, Michael W. Parker, Mark R. Ashton, Brett Roberts, Angel F. Lopez, Darren J. Kelly
Publikováno v:
Science translational medicine. 13(612)
Drug repurposing is promoted as a cost- and time-effective mechanism for providing new medicines. Often, however, there is insufficient consideration by academic researchers of the processes required to ensure that a repurposed drug can be used for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fd4678be2e05d0047237accbbe9583
https://pubmed.ncbi.nlm.nih.gov/34550729
https://pubmed.ncbi.nlm.nih.gov/34550729
Publikováno v:
Hypertension. 78
Using a genome wide association study (GWAS), we identified a locus on the promoter of the human uromodulin (UMOD) gene associating with primary hypertension. In this study we aimed to identify genotype-differential protein binding partners which inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ab14c26aa7c3a481fef6fda28b8b02
https://doi.org/10.1161/hyp.78.suppl_1.08
https://doi.org/10.1161/hyp.78.suppl_1.08
Publikováno v:
Diabetes. 70
The COVID-19 pandemic affects many aspects of diabetes care including loss of access to healthcare due to clinic closures or insurance issues, fear of accessing care due to potential COVID exposures, and food/medication insecurity. Little is known ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adbcd3584a44efa9777e864eda5d62df
https://doi.org/10.2337/db21-1044-p
https://doi.org/10.2337/db21-1044-p