Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Simon Faissner"'
Autor:
Hasan Hüseyin Hendek, Alina Blusch, Neele Heitmann, Sarah Oberhagemann, Seray Demir, Xiomara Pedreiturria, Ralf Gold, Simon Faissner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract So far, only a small number of medications are effective in progressive multiple sclerosis (MS). The sphingosine-1-phosphate-receptor (S1PR)-1,5 modulator siponimod, licensed for progressive MS, is acting both on peripheral immune cells and
Externí odkaz:
https://doaj.org/article/893365440976485ea1a55231324646ed
Autor:
Simon Faissner, Marielena Bongert, Paulina Trendelenburg, Sandra Thiel, Takashi Yamamura, Kerstin Hellwig, Ralf Gold
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Pregnancy in patients with multiple sclerosis (MS) is accompanied by a decline of relapse activity with increased risk of relapses 3 months post-partum, for unknown reasons. Eomesodermin + T-helper cells (Eomes + Th cells) are known to me
Externí odkaz:
https://doaj.org/article/def04d32359b4f41adfa56938d6d416f
Autor:
Antonios Bayas, Achim Berthele, Norbert Blank, Peter Dreger, Simon Faissner, Manuel A. Friese, Lisa-Ann Gerdes, Oliver Martin Grauer, Vivien Häussler, Christoph Heesen, Dietlinde Janson, Mirjam Korporal-Kuhnke, Markus Kowarik, Nikolaus Kröger, Jan D. Lünemann, Roland Martin, Uwe Meier, Sven Meuth, Paolo Muraro, Michael Platten, Lucas Schirmer, Klarissa Hanja Stürner, Jan Patrick Stellmann, Christof Scheid, Florian Then Bergh, Clemens Warnke, Brigitte Wildemann, Tjalf Ziemssen
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: While substantial progress has been made in the development of disease-modifying medications for multiple sclerosis (MS), a high percentage of treated patients still show progression and persistent inflammatory activity. Autologous haemat
Externí odkaz:
https://doaj.org/article/9ebac6238a0044049f1e01a530d4bd56
Autor:
Antonios Bayas, Monika Christ, Simon Faissner, Juliane Klehmet, Refik Pul, Thomas Skripuletz, Sven G. Meuth
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Although the understanding of secondary progressive multiple sclerosis (SPMS) is evolving, early detection of relapse-independent progression remains difficult. This is further complicated by superimposed relapses and compensatory mechanisms that all
Externí odkaz:
https://doaj.org/article/64720877ffa24ba0bb45045a90bb1664
Autor:
Simon Faissner, Neele Heitmann, Ricarda Rohling, Ulas Ceylan, Marielena Bongert, Carlos Plaza-Sirvent, Corinna Marheinecke, Xiomara Pedreiturria, Ilya Ayzenberg, Kerstin Hellwig, Ingo Schmitz, Stephanie Pfaender, Ralf Gold
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 15 (2022)
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has tremendous implications for the management of patients with autoimmune conditions such as multiple sclerosis (MS) under immune therapies targeting CD20 + B cell
Externí odkaz:
https://doaj.org/article/a4d057ff0a6b4ddcb77dc1af21113424
Autor:
Clara Bessen, Carlos Plaza-Sirvent, Agit Simsek, Jaydeep Bhat, Corinna Marheinecke, Doris Urlaub, Petra Bonowitz, Sandra Busse, Sabrina Schumann, Elena Vidal Blanco, Adriane Skaletz-Rorowski, Norbert H. Brockmeyer, Oliver Overheu, Anke Reinacher-Schick, Simon Faissner, Carsten Watzl, Stephanie Pfaender, Anja Potthoff, Ingo Schmitz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the development of vaccines, which protect healthy people from severe and life-threatening Covid-19, the immunological responses of people with secondary immunodeficiencies to these vaccines remain incompletely understood. Here, we investigat
Externí odkaz:
https://doaj.org/article/abc6f45fd07d4397b50f0ec012acf870
Autor:
Hannah Schulze, Jeyanthan Charles James, Nadine Trampe, Daniel Richter, Thivya Pakeerathan, Nadine Siems, Ilya Ayzenberg, Ralf Gold, Simon Faissner
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectiveRegarding pathogenesis, clinical manifestations, at-risk individuals, and diagnostic methods for stratifying patients for therapeutic approaches, our understanding of post-COVID syndrome is limited. Here, we set out to assess sociodemographi
Externí odkaz:
https://doaj.org/article/a7b4e1e5ffa149deaecfcaa788938639
Autor:
Daniel Richter, Simon Faissner, Dirk Bartig, Lars Tönges, Kerstin Hellwig, Ilya Ayzenberg, Christos Krogias, Ralf Gold
Publikováno v:
Neurological Research and Practice, Vol 3, Iss 1, Pp 1-8 (2021)
Abstract Background Since the coronavirus disease 2019 (COVID-19) has risen, several risk factors have been identified, predicting a worse outcome. It has been speculated that patients with Multiple sclerosis (MS) have an increased risk for a severe
Externí odkaz:
https://doaj.org/article/06b709bf719f4c57b25d278ad373d9a0
Autor:
Simon Faissner, Neele Heitmann, Carlos Plaza-Sirvent, Paulina Trendelenburg, Ulas Ceylan, Jeremias Motte, Clara Bessen, Doris Urlaub, Carsten Watzl, Oliver Overheu, Anke Reinacher-Schick, Kerstin Hellwig, Stephanie Pfaender, Ingo Schmitz, Ralf Gold
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveThe pandemic induced by SARS-CoV-2 has huge implications for patients with immunosuppression that is caused by disorders or specific treatments. Especially approaches targeting B cells via anti-CD20 therapy are associated with impaired humor
Externí odkaz:
https://doaj.org/article/16755a7f2810435ca56819e9ce9af063
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 15 (2022)
Background: The role of neuroinflammation and autoimmune processes in neurodegenerative diseases is not fully understood. Activation of microglia with expression of proinflammatory cytokines supports the hypothesis that immune processes may play an i
Externí odkaz:
https://doaj.org/article/7aa581f765f24c8bb27fce46d6795f5e