Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Simon F. Merz"'
Autor:
Simon F. Merz, C. Peter Bengtson, Clara Tepohl, Anna M. Hagenston, Hilmar Bading, Carlos Bas-Orth
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Glutamate toxicity is a pathomechanism that contributes to neuronal cell death in a wide range of acute and chronic neurodegenerative and neuroinflammatory diseases. Activation of the N-methyl-D-aspartate (NMDA)-type glutamate receptor and b
Externí odkaz:
https://doaj.org/article/648e0668ce8748c3b8ce691c929aede6
Autor:
Lorna Hayden, Tiia Semenoff, Verena Schultz, Simon F. Merz, Katie J. Chapple, Moses Rodriguez, Arthur E. Warrington, Xiaohong Shi, Clive S. McKimmie, Julia M. Edgar, Katja Thümmler, Chris Linington, Marieke Pingen
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract Progressive multi-focal leukoencephalopathy (PML) is a potentially fatal encephalitis caused by JC polyomavirus (JCV). PML principally affects people with a compromised immune system, such as patients with multiple sclerosis (MS) receiving t
Externí odkaz:
https://doaj.org/article/134b9017783e48d094d6013af6dc4be8
Autor:
Lea Bornemann, Marc Schuster, Saskia Schmitz, Charlyn Sobczak, Clara Bessen, Simon F. Merz, Karl-Heinz Jöckel, Thomas Haverkamp, Matthias Gunzer, Joachim R. Göthert
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background The identification of pathologically altered neutrophil granulocyte migration patterns bears strong potential for surveillance and prognostic scoring of diseases. We recently identified a strong correlation between impaired neutro
Externí odkaz:
https://doaj.org/article/36e4a32763d44000b2d08de4f6500fda
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensio
Externí odkaz:
https://doaj.org/article/3e96cf3e564a4e068419e2da632f2557
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d9923d29d593469cb22f223c62a1ff70
Autor:
Simon F. Merz, Philipp Jansen, Lea Bornemann, Ingo Stoffels, Andreas Kraus, Ricarda Ulankiewicz, Zülal Cibir, Klaus G. Griewank, Eva Hadaschik, Matthias Gunzer, Gernot Ebel, Tobias Schimming, Joachim Klode, Timo Aspelmeier, Dirk Schadendorf, Sven Brandau
Publikováno v:
European journal of cancer (Oxford, England : 1990). 159
Introduction Many cancer guidelines include sentinel lymph node (SLN) staging to identify microscopic metastatic disease. Current SLN analysis of melanoma patients is effective but has the substantial drawback that only a small representative portion
Autor:
Carlos Bas-Orth, Clara Tepohl, Hilmar Bading, C. Peter Bengtson, Anna M. Hagenston, Simon F. Merz
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Glutamate toxicity is a pathomechanism that contributes to neuronal cell death in a wide range of acute and chronic neurodegenerative and neuroinflammatory diseases. Activation of theN-methyl-D-aspartate (NMDA)-type glutamate receptor and breakdown o
Autor:
Marieke Pingen, Katie J. Chapple, Tiia Semenoff, Clive S. McKimmie, Lorna Hayden, Christopher Linington, Arthur E. Warrington, Xiaohong Shi, Julia M. Edgar, Verena Schultz, Moses Rodriguez, Katja Thümmler, Simon F. Merz
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Progressive multi-focal leukoencephalopathy (PML) is a potentially fatal encephalitis caused by JC polyomavirus (JCV). PML principally affects people with a compromised immune system, such as patients with multiple sclerosis (MS) receiving treatment
Autor:
Marie-Theres Binder, Annette Stahl, Raja Atreya, Simon F. Merz, Lisa Lou Schulze, Lea Bornemann, Imke Atreya, Sebastian Zundler, Timo Rath, Karen A-M Ullrich, Lena Schleier, Markus F. Neurath, Maximilian Wiendl, Emily Becker, Matthias Gunzer, Anja Schulz-Kuhnt, Alastair J.M. Watson, Clemens Neufert, Karin Heidbreder
ObjectiveTo study the role of α4β7 integrin for gut homing of monocytes and to explore the biological consequences of therapeutic α4β7 inhibition with regard to intestinal wound healing.DesignWe studied the expression of homing markers on monocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd802faa3c720f551b97690000bbacf
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85065772272
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85065772272
Autor:
Alexandra Ohs, Daniel R. Engel, Wolfgang Baum, Stefan Landgraeber, Astrid M. Westendorf, Oliver Kraff, Alexandra Brenzel, Gerhard Krönke, Lasse Kling, Jens V. Stein, Alexandra Adamczyk, Marcel Dudda, Thomas Kamradt, Manfred Rohde, Matthias Gunzer, Stefanie C. Lang, Daniela Weidner, Daniel Hoffmann, Georg Schett, Anja Hasenberg, Silke Christiansen, Martin Herrmann, Ibrahim Hawwari, Sylvia Müller, Sylvia Voortmann, Stephan Culemann, Renzo Danuser, Andrea Vortkamp, Annette I. Garbe, Anika Grüneboom, Sophie Henneberg, Simon F. Merz, Marcus Jäger, Kristina Zec, Harald H. Quick, Lea Bornemann, Manuela Wuelling, Kolja Gelse, Mike Hasenberg
Publikováno v:
Nature metabolism
International
Germany
Nature Metabolism
International
Germany
Nature Metabolism
Closed circulatory systems underlie the function of vertebrate organs, but in long bones their structure is unclear although they constitute the exit route for bone marrow (BM) leukocytes. To understand neutrophil migration from BM, we studied the va