Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Simon F. De Meyer"'
Unusual Histopathological Findings in Mechanically Removed Stroke Thrombi – A Multicenter Experience
Autor:
Oskar Aspegren, Senna Staessens, Sarah Vandelanotte, Linda Desender, Charlotte Cordonnier, Laurent Puy, Nicolas Bricout, Simon F. De Meyer, Tommy Andersson, Fabian Arnberg
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundSeveral studies have investigated the histopathology of mechanically retrieved thrombi from stroke patients. Thrombi with unusual components constitute about 1–2% of all stroke thrombi in clinical practice. Knowledge about these rare comp
Externí odkaz:
https://doaj.org/article/cd6e9a7956134a67a3650c252422278f
Autor:
Senna Staessens, Simon F. De Meyer
Publikováno v:
Platelets, Vol 32, Iss 3, Pp 331-339 (2021)
The structure of stroke thrombi has gained an increasing amount of interest in recent years. The advent of endovascular thrombectomy has offered the unique opportunity to provide and analyze thrombi removed from ischemic stroke patients. It has becom
Externí odkaz:
https://doaj.org/article/6b8940f9b0354bba9ffc617e1444e8e3
Autor:
Senna Staessens, Olivier François, Linda Desender, Peter Vanacker, Tom Dewaele, Raf Sciot, Karen Vanhoorelbeke, Tommy Andersson, Simon F. De Meyer
Publikováno v:
Thrombosis Journal, Vol 19, Iss 1, Pp 1-7 (2021)
Abstract Background Mechanical removal of a thrombus by thrombectomy can be quite challenging. For reasons that are not fully understood, some thrombi require multiple passes to achieve successful recanalization, whereas other thrombi are efficiently
Externí odkaz:
https://doaj.org/article/022fd23ae42640719e4d28b7bbe959fb
Autor:
Jens Van Bael, Aline Vandenbulcke, Abdelhakim Ahmed-Belkacem, Jean-François Guichou, Jean-Michel Pawlotsky, Jelle Samyn, Arjan D. Barendrecht, Coen Maas, Simon F. De Meyer, Karen Vanhoorelbeke, Claudia Tersteeg
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7163 (2023)
Procoagulant platelets are associated with an increased risk for thrombosis. Procoagulant platelet formation is mediated via Cyclophilin D (CypD) mediated opening of the mitochondrial permeability transition pore. Inhibiting CypD activity could there
Externí odkaz:
https://doaj.org/article/9dacc18342144244b68ab4ef4aa16ab8
Autor:
Kadri Kangro, Elien Roose, An‐Sofie Schelpe, Edwige Tellier, Gilles Kaplanski, Jan Voorberg, Simon F. De Meyer, Andres Männik, Karen Vanhoorelbeke
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 918-930 (2020)
Abstract Background In immune‐mediated thrombotic thrombocytopenic purpura (iTTP), patients develop an immune response against the multidomain enzyme ADAMTS13. ADAMTS13 consists of a metalloprotease (M) and disintegrin‐like (D) domain, 8 thrombos
Externí odkaz:
https://doaj.org/article/1b08d655e5664beab1e9d966ee70984e
Autor:
Thao-Thy Pham, Chuchard Punsawad, Supattra Glaharn, Simon F. De Meyer, Parnpen Viriyavejakul, Philippe E. Van den Steen
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-13 (2019)
Abstract Background Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an understudied complication of malaria and is characterized by pulmonary inflammation and disruption of the alveolar-capillary membrane. Its pathogenesis remains
Externí odkaz:
https://doaj.org/article/c1a8deac15034cdca69708b4a579af54
Autor:
Bas Calcoen, Nico Callewaert, Aline Vandenbulcke, Winnie Kerstens, Maya Imbrechts, Thomas Vercruysse, Kai Dallmeier, Johan Van Weyenbergh, Piet Maes, Xavier Bossuyt, Dorinja Zapf, Kersten Dieckmann, Kim Callebaut, Hendrik Jan Thibaut, Karen Vanhoorelbeke, Simon F. De Meyer, Wim Maes, Nick Geukens
Publikováno v:
Viruses, Vol 14, Iss 6, p 1257 (2022)
To mitigate the massive COVID-19 burden caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), several vaccination campaigns were initiated. We performed a single-center observational trial to monitor the mid- (3 months) and long-ter
Externí odkaz:
https://doaj.org/article/3f01fa74e2bc4897a3e3a5fcff302008
Autor:
Senna Staessens, Frederik Denorme, Olivier Francois, Linda Desender, Tom Dewaele, Peter Vanacker, Hans Deckmyn, Karen Vanhoorelbeke, Tommy Andersson, Simon F. De Meyer
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is focused on fast and efficient removal of the occluding thrombus, either via intravenous thrombolysis or via endovascular thrombectomy. Recanalization, however,
Externí odkaz:
https://doaj.org/article/e1e92a720b2d41afbc21552ce6cfc252
Autor:
Frederik Denorme, Kimberly Martinod, Aline Vandenbulcke, Cécile V. Denis, Peter J. Lenting, Hans Deckmyn, Karen Vanhoorelbeke, Simon F. De Meyer
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
von Willebrand factor (VWF) plays an important role in ischemic stroke. However, the exact mechanism by which VWF mediates progression of ischemic stroke brain damage is not completely understood. Using flow cytometric analysis of single cell suspens
Externí odkaz:
https://doaj.org/article/c5f984ac37b94a639ce7a6347e4d62f8
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
von Willebrand factor (VWF) and platelets are key mediators of normal hemostasis. At sites of vascular injury, VWF recruits platelets via binding to the platelet receptor glycoprotein Ibα (GPIbα). Over the past decades, it has become clear that man
Externí odkaz:
https://doaj.org/article/0724804253dc4247ab6af53fb88a4204