Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Simon Eaglestone"'
Autor:
Julien Baruteau, Sharon C. Cunningham, Berna Seker Yilmaz, Dany P. Perocheau, Simon Eaglestone, Derek Burke, Adrian J. Thrasher, Simon N. Waddington, Leszek Lisowski, Ian E. Alexander, Paul Gissen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 135-146 (2021)
X-linked inherited ornithine transcarbamylase deficiency (OTCD) is the most common disorder affecting the liver-based urea cycle, a pathway enabling detoxification of nitrogen waste and endogenous arginine biosynthesis. Patients develop acute hyperam
Externí odkaz:
https://doaj.org/article/10be24db36dd4d05b36ea1c89d212f01
Autor:
Kjersti Baksaas-Aasen, Lewis Gall, Simon Eaglestone, Claire Rourke, Nicole. P. Juffermans, J. Carel Goslings, Paal Aksel Naess, Susan van Dieren, Sisse Rye Ostrowski, Jakob Stensballe, Marc Maegele, Simon J. Stanworth, Christine Gaarder, Karim Brohi, Per I. Johansson
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Traumatic injury is the fourth leading cause of death globally. Half of all trauma deaths are due to bleeding and most of these will occur within 6 h of injury. Haemorrhagic shock following injury has been shown to induce a clotti
Externí odkaz:
https://doaj.org/article/3b99aa624f9244f485eed3f1e729e4ea
Autor:
Karim Brohi, Simon Eaglestone
Publikováno v:
Programme Grants for Applied Research, Vol 5, Iss 19 (2017)
Introduction: Dysfunction of the coagulation system, termed trauma-induced coagulopathy (TIC), is a major problem in patients who bleed after injury. Trauma haemorrhage is considered one of the leading preventable causes of death worldwide. Deaths oc
Externí odkaz:
https://doaj.org/article/d812936d297b4c4b8e9a6223d9c8b3d1
Autor:
Sharon C. Cunningham, Julien Baruteau, Derek Burke, Adrian J. Thrasher, Berna Seker Yilmaz, Simon Eaglestone, Paul Gissen, Simon N. Waddington, Ian E. Alexander, Dany P. Perocheau, Leszek Lisowski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 135-146 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
X-linked inherited ornithine transcarbamylase deficiency (OTCD) is the most common disorder affecting the liver-based urea cycle, a pathway enabling detoxification of nitrogen waste and endogenous arginine biosynthesis. Patients develop acute hyperam
Autor:
Dany P, Perocheau, Sharon, Cunningham, Juhee, Lee, Juan, Antinao Diaz, Simon N, Waddington, Kimberly, Gilmour, Simon, Eaglestone, Leszek, Lisowski, Adrian J, Thrasher, Ian E, Alexander, Paul, Gissen, Julien, Baruteau
Publikováno v:
Human Gene Therapy
Recombinant adeno-associated virus (rAAV) vectors are a promising platform for in vivo gene therapy. The presence of neutralizing antibodies (Nab) against AAV capsids decreases cell transduction efficiency and is a common exclusion criterion for part
Autor:
Martin A. Schreiber, Christine Gaarder, Paal Aksel Naess, Pieter Joosse, Marc Maegele, Thomas Brockamp, Nils Oddvar Skaga, Tahnee L. Groat, Philip C. Spinella, Matthew A. Borgman, Rolf Lefering, Karim Brohi, Simon Eaglestone, J. Carel Goslings, Mitchell J. Cohen
Publikováno v:
Critical care (London, England), 17(4). Springer Science + Business Media
Brockamp, Thomas; Maegele, Marc; Gaarder, Christine; Goslings, J; Cohen, Mitchell J; Lefering, Rolf; et al.(2013). Comparison of the predictive performance of the BIG, TRISS and PS09 score in an adult trauma population derived from multiple international trauma registries. Critical Care, 17(4), R134. doi: http://dx.doi.org/10.1186/cc12813. Retrieved from: http://www.escholarship.org/uc/item/17p7s1jd
Critical Care
Brockamp, Thomas; Maegele, Marc; Gaarder, Christine; Goslings, J; Cohen, Mitchell J; Lefering, Rolf; et al.(2013). Comparison of the predictive performance of the BIG, TRISS and PS09 score in an adult trauma population derived from multiple international trauma registries. Critical Care, 17(4), R134. doi: http://dx.doi.org/10.1186/cc12813. Retrieved from: http://www.escholarship.org/uc/item/17p7s1jd
Critical Care
Background The BIG score (Admission base deficit (B), International normalized ratio (I), and Glasgow Coma Scale (G)) has been shown to predict mortality on admission in pediatric trauma patients. The objective of this study was to assess its perform