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pro vyhledávání: '"Simon E Regnell"'
Autor:
Simon E Regnell, Martin J Hessner, Shuang Jia, Lina Åkesson, Hans Stenlund, Thomas Moritz, Daria La Torre, Åke Lernmark
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171372 (2017)
Type 1 diabetes is associated with abberations of fat metabolism before and after the clinical onset of disease. It has been hypothesized that the absence of the effect of insulin in the liver contributes to reduced hepatic fat synthesis. We measured
Externí odkaz:
https://doaj.org/article/7c49fd896a30464f8ddd9eec1d6dabc5
Autor:
Simon E. Regnell, Åke Lernmark
Publikováno v:
Diabetologia
Underlying type 1 diabetes is a genetic aetiology dominated by the influence of specific HLA haplotypes involving primarily the class II DR-DQ region. In genetically predisposed children with the DR4-DQ8 haplotype, exogenous factors, yet to be identi
Autor:
Åke Lernmark, Martin J. Hessner, Shuang Jia, Lina Åkesson, Daria La Torre, Thomas Moritz, Simon E. Regnell, Hans Stenlund
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171372 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171372 (2017)
Type 1 diabetes is associated with abberations of fat metabolism before and after the clinical onset of disease. It has been hypothesized that the absence of the effect of insulin in the liver contributes to reduced hepatic fat synthesis. We measured
Autor:
Simon E. Regnell, Cooper Martin
Publikováno v:
British Journal of Clinical Pharmacology. 77:21-30
The cannabinoid 1 receptor (CB1R) has a well-established role in appetite regulation. Central CB1R antagonists, notably rimonabant, induced weight loss and improved the metabolic profile in obese individuals, but were discontinued due to psychiatric
Autor:
Peter Leander, Pernilla Peterson, Sven Månsson, Åke Lernmark, Lena Trinh, Simon E. Regnell, H. Elding Larsson, Per Broberg
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 33(10)
AIMS: People with Type 1 diabetes have smaller pancreases than healthy individuals. Several diseases causing pancreatic atrophy are associated with pancreatic steatosis, but pancreatic fat in Type 1 diabetes has not been measured. This cross-sectiona
Autor:
Simon E. Regnell
Publikováno v:
Hepatology Research. 43:131-138
The role of cannabinoids in fatty liver disease has been increasingly acknowledged in recent years, and it has been suggested that drugs targeting peripheral cannabinoid receptors could have therapeutic use. Development of such drugs would require a
Autor:
Helena Elding Larsson, Sven Månsson, Per Broberg, Lena Trinh, Simon E. Regnell, Pernilla Peterson, Åke Lernmark, Peter Leander
Publikováno v:
Metabolism: clinical and experimental. 64(8)
Introduction Children with type 1 diabetes have been identified as a risk group for non-alcoholic fatty liver disease (NAFLD). The aim was to compare total hepatic fat fraction and fat distribution across Couinaud segments in children with type 1 dia
Autor:
Åke Lernmark, Simon E. Regnell
Publikováno v:
The review of diabetic studies : RDS. 8(4)
Islet autoimmunity in type 1 diabetes results in the loss of the pancreatic β-cells. The consequences of insulin deficiency in the portal vein for liver fat are poorly understood. Under normal conditions, the portal vein provides 75% of the liver bl