Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Simon Drescher"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 995-1007 (2017)
In the present work, we describe the synthesis of a single-chain, phenylene-modified bolalipid with two phosphocholine headgroups, PC-C18pPhC18-PC, using a Sonogashira cross-coupling reaction as a key step. The aggregation behaviour was studied as a
Externí odkaz:
https://doaj.org/article/a8741cf7bf80482599b92148b67531d0
Autor:
Simon Drescher, Peter van Hoogevest
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1235 (2020)
This review summarizes the research on phospholipids and their use for drug delivery related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that have been approved by the PRC since 2017 and are currently still ongoing
Externí odkaz:
https://doaj.org/article/9c4018d072ff427ab7d00f269bae3c68
Autor:
Nathalie Goergen, Matthias Wojcik, Simon Drescher, Shashank Reddy Pinnapireddy, Jana Brüßler, Udo Bakowsky, Jarmila Jedelská
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 307 (2019)
The alarming growth of multi-drug resistant bacteria has led to a quest for alternative antibacterial therapeutics. One strategy to circumvent the already existing resistance is the use of photodynamic therapy. Antimicrobial photodynamic therapy (aPD
Externí odkaz:
https://doaj.org/article/0e6755383e1a4fbc9901800d4aaf4d78
Autor:
Simon Drescher, Kai Gruhle, Vasil M. Garamus, Andrea Sinz, Christian Schwieger, Julia Dorner, Annette Meister, Hauke Lilie, Christian Ihling, Patricia Korn, Daniel Ramsbeck
Publikováno v:
Dorner, J.; Korn, P.; Gruhle, K.; Ramsbeck, D.; Garamus, V.; Lilie, H.; Meister, A.; Schwieger, C.; Ihling, C.; Sinz, A.; Drescher, S.: A Diazirine-Modified Membrane Lipid to Study Peptide/Lipid Interactions – Chances and Challenges. In: Chemistry-A European Journal. Vol. 27 (2021) 59, 14586-14593. (DOI: /10.1002/chem.202102048)
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
Although incorporation of photo‐activatable lipids into membranes potentially opens up novel avenues for investigating interactions with proteins, the question of whether diazirine‐modified lipids are suitable for such studies, remains under deba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361ba8379c6323d4b71ac206abf437e7
https://doi.org/10.1002/chem.202102048
https://doi.org/10.1002/chem.202102048
Publikováno v:
Physical Chemistry Chemical Physics. 23:5325-5339
How does a small change in the structure of a phospholipid affect its supramolecular assembly? In aqueous suspensions, the substitution of one ester linkage in DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) by an ether linkage alters its phase be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89375861dafffe959102d91026dfffee
https://doi.org/10.1039/d0cp06520j
https://doi.org/10.1039/d0cp06520j
Autor:
Simon Drescher
Publikováno v:
Rhetorik. 39:137-141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1963dad0ac66ca2a99125540d11efe4
https://doi.org/10.1515/rhet-2020-0014
https://doi.org/10.1515/rhet-2020-0014
Autor:
Christian Schwieger, Christian Ihling, Simon Drescher, Matthias C. Hoffmann, Dariush Hinderberger
Publikováno v:
Langmuir. 36:12804-12815
In this study, we characterized monolayers of an azide-modified lipid at the air-water interface, pure and in its mixtures with the model lipid DPPC, with the aim of proving its potential to be applied for photo-cross-linking with other molecules. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea45bbc74b8a6e3d060b80bb1894681
https://doi.org/10.1021/acs.langmuir.0c01726
https://doi.org/10.1021/acs.langmuir.0c01726
Publikováno v:
Organic & Biomolecular Chemistry. 18:3585-3598
Six single-chain, 1,32-alkyl-branched bis(phosphocholines) PC-C32(1,32Cm)-PC have been synthesized as model lipids for naturally occurring archaeal membrane lipids. The preparation of these bipolar amphiphiles bearing lateral alkyl chains of differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3725fd4340ff03bb642489b8c45717
https://doi.org/10.1039/d0ob00534g
https://doi.org/10.1039/d0ob00534g
Autor:
Patricia Korn, Christian Schwieger, Kai Gruhle, Vasil M. Garamus, Annette Meister, Christian Ihling, Simon Drescher
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1864:184004
Although the incorporation of photo-activatable lipids into membranes potentially opens new avenues for studying interactions with peptides and proteins, the question of whether azide- or diazirine-modified lipids are suitable for such studies remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6cfe8478cd3eb0454b7a7fa432f462
https://doi.org/10.1016/j.bbamem.2022.184004
https://doi.org/10.1016/j.bbamem.2022.184004
Autor:
Kai Gruhle, Sindy Müller, Simon Drescher, Gerd Hause, Vasil M. Garamus, Christian Schwieger, Annette Meister
Publikováno v:
Langmuir. 35:12439-12450
In this study, we describe the miscibility of four azide-modified membrane phospholipids (azidolipids) with conventional phospholipids. The azidolipids bear an azide group at different positions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e2f282247e23d04a44713c3d0cc5bb
https://doi.org/10.1021/acs.langmuir.9b01842
https://doi.org/10.1021/acs.langmuir.9b01842