Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

Autor: Luke F. Gamon, Simon Dieterich, Marta T. Ignasiak, Verena Schrameyer, Michael J. Davies

Publikováno v: Redox Biology, Vol 28, Iss , Pp - (2020)

Iodide ions (I−) are an essential dietary mineral, and crucial for mental and physical development, fertility and thyroid function. I− is also a high affinity substrate for the heme enzyme myeloperoxidase (MPO), which is involved in bacterial cel

Externí odkaz: https://doaj.org/article/d505c1cd5e26413fa23c31bd840c490a

Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Autor: Michael J. Davies, Christine Y. Chuang, Astrid Hammer, Simon Dieterich, Luke F. Gamon, Adelina Rogowska-Wrzesinska, Tina Nybo, Ernst Malle, Gerald Hoefler

Publikováno v: Nybo, T, Dieterich, S, Gamon, L F, Chuang, C Y, Hammer, A, Hoefler, G, Malle, E, Rogowska-Wrzesinska, A & Davies, M J 2019, ' Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase ', Redox Biology, vol. 20, pp. 496-513 . https://doi.org/10.1016/j.redox.2018.10.022
Redox Biology, Vol 20, Iss, Pp 496-513 (2019)
Redox Biology

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbabf82455fc551721050f1ce060d7ec
https://curis.ku.dk/ws/files/229271387/OA_Chlorination_and_oxidation_of_the_extracellular_matrix_protein_laminin.pdf

Optimal protocols for Hamiltonian and Schrödinger dynamics

Autor: Udo Seifert, Eckhard Dieterich, Peter-Simon Dieterich, Tim Schmiedl

Publikováno v: Journal of Statistical Mechanics: Theory and Experiment. 2009:P07013

For systems in an externally controllable time-dependent potential, the optimal protocol minimizes the mean work spent in a finite-time transition between given initial and final values of a control parameter. For an initially thermalized ensemble, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b032492c5b86fe0338cfd9210068b2
https://doi.org/10.1088/1742-5468/2009/07/p07013