Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Simon Davis"'
Publikováno v:
Frontiers in Drug Safety and Regulation, Vol 4 (2024)
Ensuring the safety of drugs is a critical aspect of healthcare. Accurate interpretation of drug safety evidence is vital to understand the safety profile and to evaluate the benefits and risks of the medicinal product. However, validity of this evid
Externí odkaz:
https://doaj.org/article/289fbd366a0d403781a355f9a5825579
Autor:
Simon Davis, Connor Scott, Janina Oetjen, Philip D. Charles, Benedikt M. Kessler, Olaf Ansorge, Roman Fischer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The spatial organisation of cellular protein expression profiles within tissue determines cellular function and is key to understanding disease pathology. To define molecular phenotypes in the spatial context of tissue, there is a need for u
Externí odkaz:
https://doaj.org/article/a9c62d9e72e54c4baedf487a7e9f1c8a
Autor:
Dannielle Wellington, Zixi Yin, Zhanru Yu, Raphael Heilig, Simon Davis, Roman Fischer, Suet Ling Felce, Elie Antoun, Philip Hublitz, Ryan Beveridge, Danning Dong, Guihai Liu, Xuan Yao, Yanchun Peng, Benedikt M. Kessler, Tao Dong
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20076- (2023)
Mutations within viral epitopes can result in escape from T cells, but the contribution of mutations in flanking regions of epitopes in SARS-CoV-2 has not been investigated. Focusing on two SARS-CoV-2 nucleoprotein CD8+ epitopes, we investigated the
Externí odkaz:
https://doaj.org/article/6ad5a37bf795450a95196caf30c2d01b
Autor:
Catarina Ginja, Silvia Guimarães, Rute R. da Fonseca, Rita Rasteiro, Ricardo Rodríguez-Varela, Luciana G. Simões, Cindy Sarmento, Maria Carme Belarte, Nabil Kallala, Joan Ramon Torres, Joan Sanmartí, Ana Margarida Arruda, Cleia Detry, Simon Davis, José Matos, Anders Götherström, Ana Elisabete Pires, Silvia Valenzuela-Lamas
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107196- (2023)
Summary: The Maghreb is a key region for understanding the dynamics of cattle dispersal and admixture with local aurochs following their earliest domestication in the Fertile Crescent more than 10,000 years ago. Here, we present data on autosomal gen
Externí odkaz:
https://doaj.org/article/746c87c9fcf04bc19b17c1636e177809
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 190- (2023)
Externí odkaz:
https://doaj.org/article/e17ac80400434cd494747258b7a9efea
Autor:
Margaret McAllister, Ricardo Morales, Olga Lucia Gamboa, Mariam Hovhannisyan, J.T. Galla, Moritz Dannhauer, Marty Woldorff, Simon Davis
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 300- (2023)
Externí odkaz:
https://doaj.org/article/e4f58698d968464196117f3f8cc2da2e
Autor:
Bergithe E. Oftedal, Stefano Maio, Adam E. Handel, Madeleine P. J. White, Duncan Howie, Simon Davis, Nicolas Prevot, Ioanna A. Rota, Mary E. Deadman, Benedikt M. Kessler, Roman Fischer, Nikolaus S. Trede, Erdinc Sezgin, Rick M. Maizels, Georg A. Holländer
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Oftedal et al. generate mice lacking the chaperonin subunit CCT8 in T cells. They find that loss of CCT8 leads to reduced formation of nuclear actin filaments, changes in proteostasis, defective Th2 cell polarization and T cell metabolism and a faile
Externí odkaz:
https://doaj.org/article/f3b7f22ef77541f089085a26cdea4934
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 299-300 (2023)
Externí odkaz:
https://doaj.org/article/c33a51001c43454582e2652ee6d394aa
Publikováno v:
Applied Sciences, Vol 13, Iss 7, p 4177 (2023)
Morphological integration and modularity refer to the degree of covariation between the different components of an anatomical structure. Modularity refers to structures that have components which covary strongly, but at the same time are relatively i
Externí odkaz:
https://doaj.org/article/c05e9ab7013a4823a569ee57a92e5720
Autor:
Zsolt Bagi, Yvonne Couch, Zuzana Broskova, Francisco Perez-Balderas, Tianrong Yeo, Simon Davis, Roman Fischer, Nicola R. Sibson, Benjamin G. Davis, Daniel C. Anthony
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Circulating extracellular vesicles (EVs) regulate signaling pathways via receptor-ligand interactions and content delivery, after attachment or internalization by endothelial cells. However, they originate from diverse cell populations and a
Externí odkaz:
https://doaj.org/article/80e085b716b4414290975bfd434f3a27