Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Simon D Fraser"'
Autor:
Hugh Gallagher, Jennifer Dumbleton, Tom Maishman, Amy Whitehead, Michael V. Moore, Ahmet Fuat, David Fitzmaurice, Robert A. Henderson, Joanne Lord, Kathryn E. Griffith, Paul Stevens, Maarten W. Taal, Diane Stevenson, Simon D. Fraser, Mark Lown, Christopher J. Hawkey, Paul J. Roderick
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Chronic kidney disease (CKD) is a very common long-term condition and powerful risk factor for cardiovascular disease (CVD). Low-dose aspirin is of proven benefit in the secondary prevention of myocardial infarction (MI) and strok
Externí odkaz:
https://doaj.org/article/42ef37c6b1004525843f973e22167309
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Background In sarcoidosis, blood monocytes, circulating precursors of granuloma macrophages, display enhanced inflammatory cytokine production, reduced expression of the regulatory (inhibitory) receptor CD200R, and altered subsets defined by CD14 and
Externí odkaz:
https://doaj.org/article/43806f60b6ab49d18c30b4c13160c651
Autor:
Simon D. Fraser, Susannah Thackray-Nocera, Marica Shepherd, Rachel Flockton, Caroline Wright, Wayne Sheedy, Kayleigh Brindle, Alyn H. Morice, Paul M. Kaye, Michael G. Crooks, Simon P. Hart
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Background Chronic cough is a distressing symptom for many people with pulmonary sarcoidosis. Continuous treatment with a macrolide antibiotic may improve cough. We aimed to assess the potential efficacy of azithromycin in patients with sarcoidosis a
Externí odkaz:
https://doaj.org/article/0f0a021cce324d45a51c0e9a5b1b5864
Autor:
May Nwe Lwin, Noor Nooh, Christopher R Holroyd, Sharon X Lin, David Culliford, Simon D Fraser, Christopher J Edwards
Publikováno v:
Rheumatology. 62
Background/Aims If sustained disease control is achieved in RA then tapering is supported by recommendations. However, this may cause loss of disease control with subsequent damage. A problem in assessing tapering is the short-term nature of studies.
Autor:
Caroline E. Wright, Simon D. Fraser, Kayleigh Brindle, Alyn H. Morice, Simon P. Hart, Michael G. Crooks
Publikováno v:
ERJ Open Research, Vol 3, Iss 4 (2017)
Externí odkaz:
https://doaj.org/article/0916315e9bc34b3288dffac4a4205f16
Autor:
Paul M. Kaye, Simon P. Hart, Susannah Thackray-Nocera, Alyn H. Morice, Rachel Flockton, Michael G. Crooks, Marica Shepherd, Kayleigh Brindle, Simon D. Fraser, Caroline Wright, W. Sheedy
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 6, Iss 4 (2020)
article-version (VoR) Version of Record
ERJ Open Research, Vol 6, Iss 4 (2020)
Background Chronic cough is a distressing symptom for many people with pulmonary sarcoidosis. Continuous treatment with a macrolide antibiotic may improve cough. We aimed to assess the potential efficacy of azithromycin in patients with sarcoidosis a
Publikováno v:
The British journal of general practice : the journal of the Royal College of General Practitioners. 73(726)
BackgroundTreatment burden is a patient-centred concept describing the effort required of people to look after their health and the impact this has on their functioning and wellbeing. High treatment burden is more likely for people with multiple long
Autor:
Holly N. Wilkinson, James D. Williamson, Alyn H. Morice, Simon D. Fraser, Yvette A. Hayman, Jesse Vance, Laura R. Sadofsky, Jorge Cervantes, Simon P. Hart
Publikováno v:
Lung
Purpose There is currently no true macrophage cell line and in vitro experiments requiring these cells currently require mitogenic stimulation of a macrophage precursor cell line (THP-1) or ex vivo maturation of circulating primary monocytes. In this
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research
article-version (VoR) Version of Record
Background In sarcoidosis, blood monocytes, circulating precursors of granuloma macrophages, display enhanced inflammatory cytokine production, reduced expression of the regulatory (inhibitory) receptor CD200R, and altered subsets defined by CD14 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105b8c8ce2656fc5e1a616e85ae6a53c
https://eprints.whiterose.ac.uk/181721/1/00804_2020.full.pdf
https://eprints.whiterose.ac.uk/181721/1/00804_2020.full.pdf
Autor:
Simon D Fraser, Maarten Taal
Publikováno v:
British journal of hospital medicine (London, England : 2005). 81(6)
Reduced glomerular filtration rate and presence of albuminuria are both associated with increased risk of several poor outcomes. People with chronic kidney disease also commonly suffer from lower quality of life than their age-matched peers. The expe