Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Simon Cronin"'
1
Akademický článek
Attenuated CSF‐1R signalling drives cerebrovascular pathology
Autor: Conor Delaney, Michael Farrell, Colin P Doherty, Kiva Brennan, Eoin O’Keeffe, Chris Greene, Kieva Byrne, Eoin Kelly, Niamh Birmingham, Paula Hickey, Simon Cronin, Savvas N Savvides, Sarah L Doyle, Matthew Campbell
Publikováno v: EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-17 (2020)
Abstract Cerebrovascular pathologies occur in up to 80% of cases of Alzheimer's disease; however, the underlying mechanisms that lead to perivascular pathology and accompanying blood–brain barrier (BBB) disruption are still not fully understood. We
Externí odkaz: https://doaj.org/article/9ed5f11fcad84fb6b9cf6cc689b7853f
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2
Akademický článek
Cohort profile: BIOVASC-late, a prospective multicentred study of imaging and blood biomarkers of carotid plaque inflammation and risk of late vascular recurrence after non-severe stroke in Ireland
Autor: Sean Murphy, Simon Cronin, Sarah Coveney, Eamon Dolan, Tim Cassidy, John Joseph McCabe, Nicola Giannotti, Jonathan McNulty, Sean Collins, Mary Barry, Joseph Harbison, Gillian Horgan, Ciaran McDonnell, Eoin Kavanagh, Shane Foley, Martin O'Connell, Michael Marnane, Peter Kelly
Publikováno v: BMJ Open, Vol 10, Iss 7 (2020)
Purpose Inflammation is important in stroke. Anti-inflammatory therapy reduces vascular events in coronary patients. 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) identifies plaque inflammation-related metabolism. However, long-te
Externí odkaz: https://doaj.org/article/e563282170c945fd953b0f2bc81f17e9
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3
Akademický článek
Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis.
Autor: Russell Lewis McLaughlin, Julie Phukan, William McCormack, David S Lynch, Matthew Greenway, Simon Cronin, Jean Saunders, Agnieska Slowik, Barbara Tomik, Peter M Andersen, Daniel G Bradley, Phil Jakeman, Orla Hardiman
Publikováno v: PLoS ONE, Vol 5, Iss 11, p e15402 (2010)
ObjectiveTo determine whether 5 single nucleotide polymorphisms (SNPs) associate with ALS in 3 different populations. We also assessed the contribution of genotype to angiogenin levels in plasma and CSF.MethodsAllelic association statistics were calc
Externí odkaz: https://doaj.org/article/e3048d6aaff64f5992df97bb9a6c23ad
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5
Moyamoya disease and moyamoya syndrome in Ireland: patient demographics, mode of presentation and outcomes of EC-IC bypass surgery
Autor: Darach Crimmins, Dominick J. H. McCabe, Peter Boers, David Williams, Sean M. Murphy, Mary O'Regan, Peter J. Kelly, Mohsen Javadpour, Ronan J. Doherty, Desmond O'Neill, Christopher McGuigan, Simon Cronin, Bryan Lynch, Niall Tubridy, John Caird, David Webb, Joan T. Moroney, Mary D. King
Publikováno v: Irish Journal of Medical Science (1971 -). 190:335-344
There are no previously published reports regarding the epidemiology and characteristics of moyamoya disease or syndrome in Ireland. To examine patient demographics, mode of presentation and the outcomes of extracranial-intracranial bypass surgery in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::497251d5c762c1423568a6589a5f7ab6
https://doi.org/10.1007/s11845-020-02280-w
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7
237 Systematic Review of Fibrinogen and Risk of Recurrent Stroke and Vascular Events after Ischaemic Stroke or Transient Ischaemic Attack (TIA)
Autor: John J McCabe, Peter J. Kelly, Eimear O'Reilly, Eamon Dolan, Simon Cronin, David Williams, Ronan Collins, Tim Cassidy, George Pope, Sarah Coveney, Joseph Harbison, Sean M. Murphy, Margaret O'Connor
Publikováno v: Age and Ageing. 48:iii1-iii16
Background Inflammation is thought to play an important role in atherosclerotic stroke mechanisms. There is growing interest in the prognostic role of inflammatory biomarkers as risk factors for recurrent vascular events, after ischaemic stroke or tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1903b18de1fe890d74a18dd68ce931eb
https://doi.org/10.1093/ageing/afz102.56
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9
Carotid Plaque Inflammation Imaged by PET and Prediction of Recurrent Stroke at 5 Years
Autor: Martin O'Connell, Joseph Harbison, Nicola Giannotti, Eoin C. Kavanagh, Pol Camps-Renom, Sarah Coveney, Shane Foley, Joan Martí-Fàbregas, Sean Murphy, Peter J. Kelly, Michael Marnane, Raquel Delgado-Mederos, John McCabe, Simon Cronin, Mary Barry, Eamon Dolan, Jonathan P. McNulty, David J. Williams, Tim Cassidy, Sean P. Collins, Gillian Horgan, Ciaran O. McDonnell, Alejandro Fernández-León
Publikováno v: NEUROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Background and ObjectivesTo determine whether carotid plaque inflammation identified by 18F-fluorodeoxyglucose (18FDG)-PET is associated with late (5-year) recurrent stroke.MethodsWe did an individual-participant data pooled analysis of 3 prospective
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da09a176b1edb0027b7982814ed1761
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=5171
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10
Attenuated CSF‐1R signalling drives cerebrovascular pathology
Autor: Kiva Brennan, Eoin O'Keeffe, Paula Hickey, Eoin Kelly, Michael Farrell, Chris H. Greene, Matthew Campbell, Colin P. Doherty, Kieva Byrne, Niamh Birmingham, Sarah L. Doyle, Conor Delaney, Simon Cronin, Savvas N. Savvides
Publikováno v: EMBO Molecular Medicine
EMBO MOLECULAR MEDICINE
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
Cerebrovascular pathologies occur in up to 80% of cases of Alzheimer's disease; however, the underlying mechanisms that lead to perivascular pathology and accompanying blood–brain barrier (BBB) disruption are still not fully understood. We have ide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52550e4b23b2a73dc20ecc5821f6190
https://doi.org/10.15252/emmm.202012889
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