Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Simon C, Baker"'
Autor:
Smarakan Sneha, Simon C. Baker, Andrew Green, Sarah Storr, Radhika Aiyappa, Stewart Martin, Klaus Pors
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 290 (2021)
Despite significant advances in treatment strategies over the past decade, selective treatment of breast cancer with limited side-effects still remains a great challenge. The cytochrome P450 (CYP) family of enzymes contribute to cancer cell prolifera
Externí odkaz:
https://doaj.org/article/f5c75b362136417a90020b3809b72ef4
Autor:
Simon C. Baker, Andrew S. Mason, Raphael G. Slip, Katie T. Skinner, Andrew Macdonald, Omar Masood, Reuben S. Harris, Tim R. Fenton, Manikandan Periyasamy, Simak Ali, Jennifer Southgate
Publikováno v:
Oncogene. 41:2139-2151
Limited understanding of bladder cancer aetiopathology hampers progress in reducing incidence. Mutational signatures show the anti-viral apolipoprotein B mRNA editing enzyme catalytic polypeptide (APOBEC) enzymes are responsible for the preponderance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0ff39a923413c2c43d8ddf7c4cf0c1
https://doi.org/10.1038/s41388-022-02235-8
https://doi.org/10.1038/s41388-022-02235-8
Autor:
Andrew S. Mason, Claire L. Varley, Olivia M. Foody, Xiang Li, Katie Skinner, Dawn Walker, Tony R. Larson, Daisuke Wakamatsu, Simon C. Baker, Jennifer Southgate
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11871
Urothelium is a transitional, stratified epithelium that lines the lower urinary tract, providing a tight barrier to urine whilst retaining the capacity to stretch and rapidly resolve damage. The role of glycerophospholipids in urothelial barrier fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f00fabfd1794adba0d44b1669d3b8
Autor:
Konstantin A Blagodatskikh, Vladimir M Kramarov, Ekaterina V Barsova, Alexey V Garkovenko, Dmitriy S Shcherbo, Andrew A Shelenkov, Vera V Ustinova, Maria R Tokarenko, Simon C Baker, Tatiana V Kramarova, Konstantin B Ignatov
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184507 (2017)
Whole-genome amplification (WGA) techniques are used for non-specific amplification of low-copy number DNA, and especially for single-cell genome and transcriptome amplification. There are a number of WGA methods that have been developed over the yea
Externí odkaz:
https://doaj.org/article/8f13b4071d0149deb95f6732bce576bf
Autor:
Simon C. Baker, Andrew S. Mason, Raphael G. Slip, Pontus Eriksson, Gottfrid Sjödahl, Ludwik K. Trejdosiewicz, Jennifer Southgate
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5295
Interferon gamma (IFNγ) is central to the inflammatory immune response, such as that entrained by BCG immunotherapy for bladder cancer. However, immune-mediated tumour cell killing is subject to modulation by immunoinhibitory “checkpoint” recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170f5cbb3586560d01f8d289388323eb
https://pubmed.ncbi.nlm.nih.gov/36358715
https://pubmed.ncbi.nlm.nih.gov/36358715
Publikováno v:
European Urology
Disparity between genome-wide mutations in bladder and other cancers where smoking is a risk factor raises questions about carcinogenesis in different epithelia. To develop an experimental model of bladder carcinogenesis, we clonally expanded in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a7646384712eeff7afed04ac4cf084
https://doi.org/10.1016/j.eururo.2020.03.049
https://doi.org/10.1016/j.eururo.2020.03.049
Autor:
Simon C. Baker, Andrew S. Mason, Raphael G. Slip, Pontus Eriksson, Gottfrid Sjödahl, Ludwik K Trejdosiewicz, Jennifer Southgate
Intravesical Bacillus Calmette-Guérin vaccine (BCG) is an established immunotherapeutic in bladder cancer (BlCa), provoking inflammation leading to tumour-specific immunity. Immune checkpoint blockers such as anti-PD-L1 have potential for enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d3025e822c139f95aeb0b6f4370c433
https://doi.org/10.1101/2022.02.04.22270000
https://doi.org/10.1101/2022.02.04.22270000
Autor:
Simon C, Baker, Andrew S, Mason, Raphael G, Slip, Katie T, Skinner, Andrew, Macdonald, Omar, Masood, Reuben S, Harris, Tim R, Fenton, Manikandan, Periyasamy, Simak, Ali, Jennifer, Southgate
Publikováno v:
Oncogene. 41(15)
Limited understanding of bladder cancer aetiopathology hampers progress in reducing incidence. Mutational signatures show the anti-viral apolipoprotein B mRNA editing enzyme catalytic polypeptide (APOBEC) enzymes are responsible for the preponderance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b33fbf56789a4113f02987036b5f974
https://pubmed.ncbi.nlm.nih.gov/35194151
https://pubmed.ncbi.nlm.nih.gov/35194151
Autor:
Jennifer Southgate, Reuben S. Harris, Slip Rg, Simon C. Baker, Skinner Kt, Manikandan Periyasamy, Tim R. Fenton, Masood O, Simak Ali, Andrew S. Mason, Andrew Macdonald
Limited understanding of bladder cancer aetiopathology hampers progress in reducing incidence. BK polyomavirus (BKPyV) is a common childhood infection that can be reactivated in the adult kidney leading to viruria. Here we used a mitotically-quiescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df339f945bbc651ba02eb159b34901a
https://doi.org/10.1101/2021.05.13.443803
https://doi.org/10.1101/2021.05.13.443803
Autor:
Sarah Storr, Andrew R. Green, Stewart G. Martin, Smarakan Sneha, Klaus Pors, Radhika Aiyappa, Simon C. Baker
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 290, p 290 (2021)
Biomedicines, Vol 9, Iss 290, p 290 (2021)
Despite significant advances in treatment strategies over the past decade, selective treatment of breast cancer with limited side-effects still remains a great challenge. The cytochrome P450 (CYP) family of enzymes contribute to cancer cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632c9132d62bf55dcb28015d26fbaf58
https://pubmed.ncbi.nlm.nih.gov/33809117
https://pubmed.ncbi.nlm.nih.gov/33809117